SOLICITATION NOTICE
B -- In Vivo Imaging services
- Notice Date
- 4/11/2017
- Notice Type
- Presolicitation
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Office of Acquisitions, Office of Management, 530 Davis Drive, Durham, North Carolina, 27713, United States
- ZIP Code
- 27713
- Solicitation Number
- NIEHS-4531161
- Archive Date
- 8/11/2017
- Point of Contact
- Teresa A. McCall, Phone: 9195410387
- E-Mail Address
-
teresa.mccall@nih.gov
(teresa.mccall@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- DELIVERY DATE: 45 days after receipt of order DESCRIPTION OF REQUIREMENT: This contract action is for the acquisition of services for which the Government intends to solicit and negotiate with only one source under the authority and procedures of Federal Acquisition Regulation (FAR) Subpart 13.106-1(b. The National Institute of Environmental Health Sciences (NIEHS), Office of Acquisitions (OA) intends to award a single source purchase order to Duke University Center for In Vivo Microscopy, 311 Research Drive, Durham, NC 27710, for the acquisition of In Vivo Imaging services to evaluate the neurotoxity of hexachlorophene in rats using magnetic resonance microscopy (MRM). It has been determined that Duke University is the source that can provide the required In Vivo Imaging services The associated North American Industrial Classification System (NAICS) code for this procurement is 541712 "Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)". Its associated Small Business Size Standard is 1,000 employees. Magnetic resonance microscopy is based on the same principles of MRI, but allows for higher resolution and sensitivity at the microscopic level down to the scale of microns. Higher resolution is achieved using encoding gradients that are at least 5X-100X higher than those of clinical human MRI systems. Greater sensitivity is enhanced by working at higher magnetic fields using specially constructed probes and specialized pulse sequences. To provide principle investigators, the ability to evaluate the neurotoxity of hexachlorophene in rats using magnetic resonance microscopy the National Toxicology Program (NTP) requires In Vivo Imaging services, from Duke's Center for In Vivo Microscopy. New higher throughput methods are now available at the Center of In Vivo Microscopy that include diffusion "stains" which are ideal for identifying lesions involving the myelinated tracks (white matter tracks) in the brain. CIVM will provide NTP with the use of a powerful imaging modality - magnetic resonance microscopy, that can acquire 500 or more cross-sectional images of the entire brain, and the ability to display them in multiple planes. These studies are being conducted to enhance the labs assessment of environmental chemicals which target the grey and white matter tracts of the brain. It is critical that a comprehensive evaluation of the nervous system is conducted in neurotoxicity studies. Factors such as the increasing occurrence of human neurological diseases and associated economical cost burden, the role of unidentified environmental stressors in neurodegenerative disorders, multiple therapeutic drug-­induced neuropathies noted in human clinical trials, and the exponential use of environmental chemicals with unknown neurotoxic potential necessitate a more extensive evaluation of the nervous system. To address these issues, the NTP modified its approaches for sampling the nervous system to include 7 sections of brain. NIEHS will solicit and negotiate directly with Duke University and no solicitation will be issued. This notice of intent is not a request for competitive proposals or quotations; however, if an interested party believes they can meet the above requirement, all responsible sources may submit a quotation which shall be considered by the agency. The quotation must be submitted in writing and must contain material in sufficient detail to allow the Government to determine if the party can perform the requirement. Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed requirement based on responses to this notice is solely within the discretion of the Government. All interested parties must express their interest and capabilities in writing via email to Teresa.McCall@nih.gov within fifteen (15) days after the date of publication of this notice. No faxed documents will be accepted. If no responsive statements are received within fifteen (15) days, an award will be made to Duke University.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIEHS/NIEHS-4531161/listing.html)
- Place of Performance
- Address: NIEHS, Research Triangle Park, North Carolina, 27709, United States
- Zip Code: 27709
- Zip Code: 27709
- Record
- SN04467632-W 20170413/170411234406-60aa593a8fc3e658464938052d0edace (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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