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FBO DAILY - FEDBIZOPPS ISSUE OF JULY 10, 2016 FBO #5343
SOURCES SOUGHT

66 -- MultiElectrode Array (MEA) Electrophysiology System for the NINDS Neuro Therapeutics Development Unit (NTDU) and Neural Differentiation Unit (NDU) - Sources Sought 4234771

Notice Date
7/8/2016
 
Notice Type
Sources Sought
 
NAICS
334516 — Analytical Laboratory Instrument Manufacturing
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 3155, MSC 9593, Bethesda, Maryland, 20892, United States
 
ZIP Code
20892
 
Solicitation Number
HHS-NIH-NIDA-SSSA-SS-494
 
Point of Contact
Danielle R. Brown, Phone: 3014802385
 
E-Mail Address
danielle.brown2@nih.gov
(danielle.brown2@nih.gov)
 
Small Business Set-Aside
Total Small Business
 
Description
Sources sought with description and requirements. The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), conducting research into the causes, treatment, and prevention of neurological disorders and stroke. The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. The NINDS Neuro Therapeutics Development Unit (NTDU) and the Neural Differentiation Unit provide a resource for investigators at NINDS and other NIH Institutes to develop neuroprotective and neuroregenerative therapeutics entities. A significant part of this work includes development of cell based assays to identify, evaluate and characterize potential agents as possible treatments for neurological disorders. Our platform requires the generation of human induced pluripotent stem cell derived neuronal cultures for evaluation, characterization and quantitation of the protective actions of new and novel neurotherapeutic strategies. To assess the functionality of these human cultures derived from both normal control and patients with neurologic diseases, electrophysiologic measurements are appropriate parameters to validate the cultures. We plan to generate Induced Pluripotent Stem Cells (iPSC) and neural stem cells (NSC) from normal controls and patients with Chronic Fatigue Syndrome (CFS) and assess the morphologic and electrophysiologic properties of the stem cell derived neuronal cultures. This may help delineate the neurobiologic properties of CFS and their molecular function as a prerequisite to
 
Web Link
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/HHS-NIH-NIDA-SSSA-SS-494/listing.html)
 
Place of Performance
Address: The place of performance shall be the National Institutes of Health, NINDS, 10 Convent Drive, Building 10, Room 7C-213, Bethesda, MD 20892-4478 USA., Bethesda, Maryland, 20892, United States
Zip Code: 20892
 
Record
SN04176599-W 20160710/160708234925-048e9e0e500e5dfcaef460bde7b8eed5 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
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