SOLICITATION NOTICE
66 -- New Aviv Optics Box, Model: FDS-561
- Notice Date
- 8/25/2015
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- HHS-NIH-NHLBI-CSB-(EB)-2015-233-DLM
- Archive Date
- 9/15/2015
- Point of Contact
- Dorothy Maxwell, Phone: 301-435-0352
- E-Mail Address
-
maxwelld@mail.nih.gov
(maxwelld@mail.nih.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- INTRODUCTION: THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR A PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) intends to negotiate and award a purchase order on a non-competitive sole source basis to AVIV Biomedical, Inc., 750 Vassar Avenue, Lakewood, New Jersey 08701-6929, to provide the following for the National Institute of Health (NIH), National Institute of Biomedical Imaging and Bioengineering (NIBIB). PRODUCT : Contract line items : 1. New Aviv Optics Box, Model: FDS-561 for the Beckman Analytical Ultracentrifuge containing 561 nm-50 mw laser and approiate long pass filter, Product Number: FDS561, Quantity: One. Background: The National Institute of Health (NIH) is the nation's leading medical research agency and the primary Federal agency seeking fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The mission of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) is to improve health by leading the development and accelerating the application of biomedical technologies. The Institute is committed to integrating the physical and engineering sciences with the life sciences to advance basic research and medical care. This is achieved through: research and development of new biomedical imaging and bioengineering techniques and devices to fundamentally improve the detection, treatment, and prevention of disease; enhancing existing imaging and bioengineering modalities; supporting related research in the physical and mathematical sciences; encouraging research and development in multidisciplinary areas; supporting studies to assess the effectiveness and outcomes of new biologics, materials, processes, devices, and procedures; developing technologies for early disease detection and assessment of health status; and developing advanced imaging and engineering techniques for conducting biomedical research at multiple scales. The goal of the Dynamics of Macromolecular Assembly section (DMA), as part of the Laboratory of Cellular Imaging and Macromolecular Biophysics (LCIMB), is the development of biophysical tools for the characterization of reversible macromolecular interactions in biological systems. A significant part of our work is focused on the development and application of methods to characterize thermodynamic and dynamic properties of chemical and biological molecules. This includes research on cutting edge detection approaches such as fluorescence detection, which has unique physical properties for sensitivity. Laboratory of Cellular Imaging and Macromolecular Biophysics (LCIMB), is well-known for the development of fluorescence detected analytical ultracentrifugation tools, using 488 nm excitation of green fluorescent protein variants. One current goal is the development of methods to study macromolecules directly in raw cell extracts, in order to make biophysical size-and-shape measurements accessible as a complementary tool to microscopic imaging. Currently, NIBIB Laboratory of Cellular Imaging and Macromolecular Biophysics have an existing fluorescence detection system for a Beckman Coulter analytical ultracentrifuge. The fluorescence detection system was previously purchased from AVIV and uses a 488 nm solid state laser to excite green fluorescent protein. During the course of scientific research, the scientific investigators have discovered that excitation wavelength of 561 nm will be highly advantageous for certain applications. Purpose and Objectives: The Laboratory of Cellular Imaging and Macromolecular Biophysics (LCIMB) is in urgent need to acquire a fluorescence detector for analytical ultracentrifugation with 561 nm optics. The purpose of this acquisition is to acquire a fluorescence detection system with 561 nm optics from AVIV Biomedical Inc., for the existing Beckman Coulter analytical ultracentrifuge. This system will allow scientific researchers to develop biophysical tools for the study of macromolecules in native cell extracts, to provide basic understanding of molecular and cellular mechanisms in diseases. Justification: AVIV Biomedical AU-FDS system will be installed into existing Beckman Coulter analytical ultracentrifuge in NIBIB laboratory. NIBIB researchers have extensive experience with an AVIV fluorescence detector with a 488 nm laser, and are therefore familiar with the performance and operation of this device. AVIV has unique expertise to build ultra-centrifugal fluorescence detectors. The requested optics box FDS-561 satisfies an important requirement: It is a module that fits into existing wiring and space constraints in the analytical ultracentrifuge, and will integrate into the existing software. There will be minimal differences in operation of the existing 488 nm laser from the requested 561 nm laser unit. Aviv is the sole manufacturer of the optics box with 561 nm laser that can be retrofitted into the existing receptacles in Beckman Coulter instrumentation. Period of Performance: Delivered Within 12 Weeks Regulatory Authority : This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b) Soliciting from a single source, only one responsible source and no other supplies or services will satisfy agency requirements. Additional Information : Industry Classification (NAICS) Code is 334516, Analytical Laboratory Instrument Manufacturing and the Small Business Size Standard is 500 Employees. The acquisition is being conducted under FAR Part 13, simplified acquisition procedures, therefore the requirements of FAR Part 6 B Competitive Requirements are not applicable (FAR Part 6.001). The resultant Contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-83 (August 5, 2015). This requirement is under the Simplified Acquisition Threshold of $150,000.00. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received August 31, 2015 and must reference synopsis number HHS-NIH-NHLBI-CSB-(EB)-2015-233-DLM, may be submitted to the National, Heart, Lung and Blood Institute, Office of Acquisition, COAC Services Branch, 6701 Rockledge Drive, Suite 6149, Bethesda, Maryland 20892-7902, Attention: Dorothy Maxwell. Response may be submitted electronically to maxwelld@mail.nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."
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- Place of Performance
- Address: NIH, Bethesda, Maryland, United States
- Record
- SN03855180-W 20150827/150826000147-f9343daeecd5f5f3a21a98d6fb441a7b (fbodaily.com)
- Source
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