SOLICITATION NOTICE
B -- NCATS Pharmacologically Active Chemical Toolbox (NPACT) commercial powder reformatting to solutions in 96-well and 384-well plates
- Notice Date
- 8/10/2015
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211 - MSC 9559, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA(SSSA)-2015-CSS-554
- Archive Date
- 8/29/2015
- Point of Contact
- Samantha A. Kelly, Phone: 3014028855
- E-Mail Address
-
samantha.kelly2@nih.gov
(samantha.kelly2@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Combined Synopsis/Solicitation Introduction: This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is HHS-NIH-NIDA(SSSA)-2015-CSS-554 and the solicitation is issued as an request for quotation (RFQ). Competition Status: This requirement is posted as contracting without conducting full and open competition. Statutory Authority: This acquisition is conducted under the authority of 41 U.S.C 3304(a)(1) under provisions of the statutory authority of FAR Subpart 6.302-1(a)(2)(i)(A)- Only one responsible source and no other supplies or services will satisfy agency requirements. North American Industry Classification System (NAICS) Code: The intended procurement classified under NAICS code 541380 with a Size Standard of $15 million. Acquisition Authority: This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source and is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-05-83-2-2, dated August 5, 2015. Description of Requirement: Background: The National Center for Advancing Translational Sciences (NCATS) is a part of the National Institutes of Health (NIH), which mission it is to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. NCATS DPI Compound Management (CoMa) has been tasked with assembling the NPACT library. DPI will include these molecules in the NCATS Pharmacologically Active Chemical Toolbox (NPACT) small molecule collection. NPACT aims to broadly cover all biological mechanisms known in literature or patents and provides information access for NCATS investigators to accelerate their research. Purpose: The purpose of this requirement is to procure testing services to solubilize 44,000 compounds in DMSO to 10mM concentration and distribute them for HTS screening to the National Center for Advancing Translational Sciences (NCATS) Division of Preclinical Innovation (DPI). Deliverables/Period of Performance: Project completion and delivery of results within six (6) months following receipt of materials from NCATS; period of performance will be defined upon award. Contractor Requirements: Specifically, the following testing services are required: 1.) The Contractor shall solubilize each 1dram barcoded vial containing ~5mg powder (DPI will provide the vial barcode, exact weight of powder in each vial to 1 decimal point, and formula weight of each sample) to 10mM in 100% DMSO solvent. 2.) The Contractor will visually verify that the powder is completely solubilized before distribution to the destination labware. 3.) If the sample cannot be dissolved to 10mM, subsequent dilutions will be attempted at 5mM, 2.5mM, and 1.25mM before distribution to the destination labware. 4.) The Contractor will distribute up to 900uL of solution to each of 2 Matrix barcoded tubes, cap each tube with a Sepraseal cap, and place them in separate barcoded Matrix racks. 5.) The Contractor will distribute 20uL solution of each sample to a different well in a 384-well plate which will be thermally heat sealed. Deliverables/Reporting Requirements: 1.)The Contractor will deliver by overnight courier at their expense to DPI the frozen solutions in Matrix racks and 384-well plates, and electronically report to DPI in Microsoft Excel format the RackID, Well Position, Matrix barcode (if applicable to the plate type), sample ID, and sample concentration in millimolar. 2.)The Contractor will return any unused portion of consumables to DPI at the end of the project and dispose of any vials and caps that have been consumed in the solubilization process. Evaluation Criteria- FAR clause 52.212-2, Evaluation - Commercial Items applies to this acquisition and the specific evaluation criteria to be included in paragraph (a) of that provisions are as follows: The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, technical, price and other factors considered. The vendor shall provide all of the services listed in the "Contractor Requirements" and "Deliverables/Reporting Requirements" section of this solicitation. Contract Type: The Government intends to issue a firm fixed price Contract for this requirement. Applicable Clauses and Provisions: All Offerors MUST be actively registered in the System for Award Management (SAM) www.sam.gov The provision of FAR clause 52.212-1, Instructions to Offerors - Commercial Items applies to this acquisition. The provision of FAR clause 52.212-2, Evaluation - Commercial Items applies to this acquisition. (a)The Government will make an award resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered to include past performance. The Government intends to issue an award on a firm fixed price Contract for these requirements on the basis of lowest price technically acceptable. (b)Award Criteria Selection of an Offeror for the award will be on the basis of lowest price technically acceptable. Technical acceptability includes an evaluation on technical factors (which encompasses experience/capability and past performance factors), and cost/price factors. Evaluation of technical acceptability will be made in accordance with the prospective Contractor's demonstrated capabilities of meeting each of the requirements as set forth in this solicitation and all applicable attachments. The merits of each proposal will be evaluated carefully. The offerors must include all specifications/services (including all brand-name or equal requirements so that the brand-name or equal status may be verified), detailed in this solicitation, in its proposal. Offeror's cost/price proposal will be evaluated for reasonableness. For a price to be reasonable, it must represent a price to the Government that a prudent person would pay when consideration is given to prices in the market. Normally, price reasonableness is established through adequate price competition, but may also be determined through cost and price analysis techniques as described in FAR 15.404. The prices quoted will be evaluated taking into consideration any price reductions. A best value analysis will be performed taking into consideration the results of the technical evaluation and price evaluation. A completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, is required with any offer submitted. The FAR clause is located at http://www.acquisition.gov/far/. This requirement may be met by completion of the provision in the System for Award Management. FAR clauses 52.212-4, Contract Terms and Conditions - Commercial Items and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial items apply to this acquisition. FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Response Format: Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement. The price quote shall include: unit price, list price, shipping and handling costs, the delivery period after contract award, delivery terms, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), the certification of business size, product or catalog numbers, product description and other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responses must be received by August 14, 2015 at 8:00AM EST and must reference number HHS-NIH-NIDA(SSSA)-2015-CSS-554. Responses may be submitted electronically to Samantha Kelly, Contract Specialist at samantha.kelly2@nih.gov. "All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency."
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