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FBO DAILY - FEDBIZOPPS ISSUE OF JULY 19, 2015 FBO #4986
SOLICITATION NOTICE

66 -- Brand Name or Equal for the purchase of a QuantStudio™ 7 Flex Real-Time PCR System

Notice Date

7/17/2015
 

Notice Type

Combined Synopsis/Solicitation
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
 

ZIP Code

20852
 

Solicitation Number

N02RC52634-83
 

Archive Date

8/18/2015
 

Point of Contact

Gwennifer K. Epps, Phone: 240-276-5445, Terry Galloway, Phone: 240-276-5384
 

E-Mail Address

eppsg@mail.nih.gov, gallowaytl@mail.nih.gov
(eppsg@mail.nih.gov, gallowaytl@mail.nih.gov)
 

Small Business Set-Aside

N/A
 

Description

I. Description of Requirement The National Cancer Institute (NCI), Center for Cancer Research (CCR), has the requirement to procure the following brand name items: a QSTUDIO7 FLX 96WFAST INST LPTP, FAST 96 WELL CALIBR INSTAL KIT, 384-WELL BLOCK UPGRADE, ARRAY CARD BLOCK UPGRADE; standard warranty manufactured by, Government Scientific Source, Inc., 12351 Sunrise Valley Drive, Reston, Virginia 20191, or Equal. This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. The combined synopsis/ solicitation number remains the same: N02RC52634-83. This solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC 20) 05-72, (January 2014) Simplified Procedures for a Commercial Item. The Government contemplates only one award of a Firm-Fixed Price contract. The Associated North America Industry Classification Code (NAICS) 334516 and the Business Size Standard is 500. It has been determined there are no opportunities to acquire green products or services for this procurement. Only one award will be made as a result of this solicitation. The Laboratory of Metabolism (LM), founded in 1996. The LM has a comprehensive research program that aims to translate basic biological findings into experimental systems used for the development of drugs and the determining the risk assessment of chemicals affecting carcinogenesis and developmentally related abnormalities leading to tumors. The lab's research has significant impact beyond its laboratory. The LM has generated unique reagents, such as recombinant cytochrome P450s; transcription factors and chromatin proteins; genetically altered mice for chromosomal protein-encoding genes; multiple nuclear receptor and transcription factor gene knock-out mice; conditional knock-out mice; tissue-specific Cre mice; P450 and nuclear receptor humanized mice; antibodies to P450s, transcription factors and chromatin components; recombinant dominant negative proteins to B-ZIP transcription factors; POLO kinase inhibitors and assay systems for cancer diagnosis that have been distributed to numerous laboratories in the U.S. and throughout the world. The Laboratory of Metabolism currently has a 10-yr old ABI 7900qRT-PCR instrument that is heavily used by many members of five research groups. The purchase of an up-graded qRT-PCR unit is needed by the Laboratory of Metabolism. Salient characteristics required are: QuantStudio TM 7 Flex Real-Time PCR System Instrument 1. The instrument is compatible with TaqMan® Array Cards, a micro fluidic device that incorporates 384 reaction chambers arrayed in a standard 384-well format. The micro fluidic device features 8 distinct loading ports, each requiring 1-100ng of RNA converted to cDNA and connected to 48 individual reaction chambers. Each reaction chamber need <2uL reaction volume. 2. The instrument has four (4) user-interchangeable blocks to accommodate 96-well, Fast 96-well low volume, 384-well plates or TaqMan® Array Cards. No service visits or recalibration are necessary after a block change. 3. The instrument's user-interchangeable blocks are accessible from the front of the instrument to maximize bench space and provide tool-free block exchange capability. 4. The instrument includes an user-interchangeable light source that is readily accessible and can be replaced from the front of the instrument. The light source has a median lifetime of at least 2000 hours. 5. The instrument can be used with 100V-240V without modification or special plug requirements. 6. The instrument includes a heated lid assembly that heats the top half of the sample plates and provides an effective seal to minimize reaction mixture evaporation. Instrument On-Board Computer 7. The instrument can run in standalone mode, without a computer attached. 8. The instrument includes a touchscreen interface that can store protocols for quick run starts from the instrument without the need for a computer. 9. Instrument's touch screen interface allows for uploading of protocols or downloading of run files using a USB interface. 10. The instrument contains on-board storage capability with capacity for a minimum of 100 standard absolute quantification run files and is designed for maximum run protection in case of network or power outage. 11. The instrument can be customized, through the touch screen, to include the correct date/time format, time zone, comma/decimal point separator, and service/calibration notifications settings. Performance 12. The instrument is designed to complete a 40 cycle real-time PCR reaction using fluorogenic 5' nuclease assay and fast chemistries in a standard 384-well plate in under 35 minutes. Instrument can also run in standard ramping mode with standard chemistry. 13. The instrument includes an OptiFlex TM System which combines 6 excitation (450-670 nm) and 6 emission (500-720 nm) filter sets to enable collection of up to 21 unique combinations of wavelengths during a single run for multiplexing. 14. The instrument supports at least two homogeneous reaction chemistries, the fluorogenic 5' nuclease assay using TaqMan® probes and the SYBR® Green DNA binding dye chemistry. 15. The instrument has real-time quantitative PCR installation specifications which demonstrate the ability to distinguish between 5,000 and 10,000 template copies with a 99.7% confidence level. Software 16. The instrument includes a copy of free software that is designed to collect and analyze the fluorescence data for the applications of absolute quantification, relative quantification, presence/absence assays, and allelic discrimination/SNP (Single Nucleotide Polymorphism) detection. 17. The instrument software will allow both TaqMan® and SYBR® chemistries in the same run by collecting different filter colors for PCR versus melt curve stages. 18. The instrument software contains a genotyping optimization tool that uses real time data to help pick the best cycle number for the genotyping call, saving run cycles and time. 19. The instrument software provides raw fluorescent data and multicomponent (segregated by dye type) data for troubleshooting of experiment. 20. The instrument software allows the conversion of Applied Biosystems® 7900HT Software and ViiA TM 7 software protocols. 21. The instrument software allows users to batch analyze up to 150 experiments simultaneously. 22. The instrument software can control the instrument and analyze instrument's data from a remote computer within the same network. 23. The instrument software provides status monitoring of 15 instruments and real time runplot from 4 instruments at a time. 24. The instrument software can send users an email notification with the attached completed run file or send a text message when instrument is started, stopped, or overdue on calibration. 25. The instrument software will allow up to 10 different users to simultaneously monitor 1 instrument. 26. The instrument software includes a ReadiApp® button that contains a link to common applications like Copy Number Variation, miRNA Gene Expression, and SNP Genotyping for quick start of runs. 27. The instrument software provides import capabilities of files from Excel®, Text, ViiA TM 7, and 7900 HT Templates. 28. The instrument software allows users to start a run in 3 mouse clicks or less. 29. The instrument software provides the ability to import a standard curve from one plate for analysis of another plate of the same instrument type. 30. The instrument software provides an endogenous control selection tool for gene expression experiments. 31. Instrument software includes statistical analysis tools like Box-Whisker plots to assess Ct distribution, scatter plots and heat maps to assess sample correlation and quality. 32. Instrument software allows users to pre-select which data to export and location of exported file. 33. The instrument software allows for command line functions for batch exporting of analyzed run files. 34. The instrument software allows user to save pre-defined analysis settings for autoexporting run data into their format of choice, including 7900HT software, ViiA TM 7 software, and RDML (Real time Data Markup Language, compliant with MIQE Guidelines) export formats. 35. The instrument software contains an optional security and auditing module that facilitates 21CFR part 11 compliance 36. The instrument software contains an optional High Resolution Melt application that allows user to specify the number of clusters/ variants, save their defined controls and analysis settings. 37. The instrument is supplied with primer and probe design software. Design 38. The instrument is available with a robotic arm capable of loading and unloading reaction plates. The resulting integrated unit is designed to provide unattended instrument operation for up to 110 384-well reaction plates, 100 TaqMan Array Microfluidic Cards, 50 96-well plates or 60 Fast 96-well plates. An Application Programming Interface (API) is included that will allow programming routines to be developed for controlling the instrument. 39. The instrument is cUL (tested to CAN/CSA standards), UL, CE, C-TICK, WEEE compliant. 40. The instrument is developed and manufactured in accordance with quality system requirements that comply with ISO 13485 standards. Vendor Service and Support 41. The instrument is provided with a limited warranty for a period of one year from the date of installation (or fifteen months from the date of shipment - whichever is earlier). A factory trained service engineer is available to perform all repairs. Optional post-warranty service contracts including next-business-day on-site repairs are available. 42. The instrument is provided with a one-day training session by a certified technical scientist (Field Application Specialist). 43. Vendor is able to supply all the necessary consumables to perform real-time quantitative PCR and SNP genotyping, including PCR reagents designed for use with the fluorogenic 5' nuclease assay, PCR reagents designed for use with SYBR® Green I dye assay chemistry, fluorogenic probes, reaction plates and adhesive plate sealing covers. PCR reagents are also available with an optional passive internal reference ROX dye to minimize well-to-well variability. 44. Vendor provides comprehensive assay design and development guidelines for real-time quantitative PCR and SNP genotyping assays. 45. Vendor offers Telephone Technical Support and Field Applications/Sales/Service Support to help solve chemistry and instrumentation problems encountered with real-time quantitative PCR and SNP genotyping. II. Delivery Contractor(s) shall deliver the instrument within 90 days after award to: NIH/NCI Bethesda, Maryland 20892. The Contractor that receives: the award will be provided with the complete mailing address and point of contact. Upon delivery, contractor must notify the NCI Contracting Officer's Representative (COR) to schedule the delivery date and time. III. Installation Contractor shall install the equipment (new) and have ready to use within seven (7) days after delivery and acceptance. IV. Payment Payment shall be made after delivery, installation, and successful operation of equipment. Payment authorization requires submission and approval of invoice to the NCI COR and NIH Commercial Accounts. BASIS FOR AWARD: Offerors must provide descriptive literature or other materials that demonstrate their offer meets the forgoing requirements. The contract will be awarded to the responsible offeror with the lowest price offer that fully meets the requirements of the solicitation. QUOTATIONS ARE DUE: August 3, 2015 at 11:00 am, EST. PROVISIONS AND CLAUSES: The following provisions and clauses will be incorporated by reference: 52.211-6 Brand Name or Equal (a) If an item in this solicitation is identified as quote mark brand name or equal, quote mark the purchase description reflects the characteristics and level of quality that will satisfy the Government's needs. The salient physical, functional, or performance characteristics that quote mark equal quote mark products must meet are specified in the solicitation. (b) To be considered for award, offers of quote mark equal quote mark products; including quote mark equal quote mark products of the brand name manufacturer, must- (1) Meet the salient physical, functional, or performance characteristic specified in this solicitation; (2) Clearly identify the item by- (i) Brand name, if any; and (ii) Make or model number; (3) Include descriptive literature such as illustrations, drawings, or a clear reference to previously furnished descriptive data or information available to the Contracting Officer; and (4) Clearly describe any modification the offeror plans to make in a product to make it conform to the solicitation requirements. Mark any descriptive material to clearly show the modification. (c) The Contracting Officer will evaluate quote mark equal quote mark products on the basis of information furnished by the offeror or identified in the offer and reasonably available to the Contracting Officer. The Contracting Officer is not responsible for locating or obtaining any information not identified in the offer. (d) Unless the offeror clearly indicates in its offer that the product being offered is an quote mark equal quote mark product, the offeror shall provide the brand name product referenced in the solicitation. (End of provision) 52.212-1 Instruction to Offerors Commercial Items 52.212-2, Evaluation Commercial Items: The purchase order will be awarded to the Lowest Price Technically Acceptable (LPTA). The award will be made on the basis of the lowest evaluated price of quotations meeting or exceeding the acceptability standards for the requirements/technical specifications stated above. The technical evaluation will be a determination based on information furnished by the vendor. The Government is not responsible for locating or securing any information which is not identified in the proposal. The Government reserves the right to make an award without discussions. 52.212-3 Offerors Representations and Certifications Commercial Items (November 2013) WITH DUNS NUMBER ADDENDUM (52.204-6 (July 2013): 52.212-4 Contract Terms and Conditions Commercial Items, applies to this acquisition. 52.212-5 Contract terms and Conditions Required to Implement Statutes or Executive Orders---Commercial Items (January 2014). The following additional FAR clauses cited in this clause are applicable: (b) The Contractor shall comply with the FAR clauses in this paragraph (b) that the Contracting Officer has indicated as being incorporated in this contract by reference to implement provisions of law or Executive orders applicable to acquisitions of commercial items: 52.203-6, Restrictions on Subcontractor Sales to the Government, with Alternate I (41 U.S.C. 253g and 10 U.S.C. 2402) 52.204-10 Reporting Executive Compensation and First Tier Subcontract Awards 52.209-6, Protecting the Government' Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment 52.219-4 Notice of Price Evaluation Preference for HUBZone Small Business Concerns 52.219-8 Utilization of Small Business Concerns 52.219-28 Post Award Small Business Program Representation 52.222-3, Convict Labor 52.222-19 Child Labor Cooperation with Authorities and Remedies 52.222-21 Prohibition of Segregated Facilities 52.222-26 Equal Opportunity 52.222-35 Equal Opportunity for Veterans 52.222-36 Affirmative Action for Workers with Disabilities 52.222-40 Notification of Employee Rights Under the National Labor Relations Act 52.222-37 Employment Reports on Veterans 52.223-18, Encouraging Contractor Policies to Ban Text Messaging while Driving 52.225-1 Buy American Act - Supplies 52.225-13 Restrictions on Certain Foreign Purchase 52.232-33 Payment by Electronic Funds Transfer System for awards Management 52.247-64, Preference for Privately-Owned U.S. Flag Commercial Vessels 52.246-2 Inspection of Supplies-Fixed Price Full text copies of the representations and certifications for other cited provisions and clauses many be obtained on line at the NCI website at http://ncioa.cancer.gov/oa-internet/reference.jsp or from Gwennifer Epps, Contracting Officer at eppsg@mail.nih.gov. Quotations must be received in the NCI-OA contracting office by 11:00 a.m. EST on August 3, 2015. Please refer to the solicitation number: N02RC52634-83 on all correspondence. No collect calls will be accepted. Faxed or electronic mail quotations will NOT be accepted. OFFERORS: Offers must be submitted on an SF-1449 with a completed 52.212-3 Offeror Representations and Certifications-Commercial Items-with DUNS Number Addendum, signed by an authorized representative of the offeror OR provide a copy of the valid certification registrations of the offeror's Central Contractor Registration (CCR) and Online Representations and Certifications Applications (ORCA) through sam.gov. All questions shall be in writing and may be addressed to the aforementioned individual noted below by August 3, 2015. No collect calls will be accepted. In order to receive an award, contractor must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representation and Certifications Applications (ORCA) through sam.gov. Primary Point of Contact: Gwennifer Epps, Contracting Officer eppsg@mail.nih.gov phone: 240-276-5445 fax: 240-276-5401
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/N02RC52634-83/listing.html)
 

Place of Performance

Address: National Cancer Institute/NIH, Building 37, Bethesda, Maryland, 20814, United States

Zip Code: 20814
 

Record

SN03800930-W 20150719/150717234633-1e82ad5666b13b47aa416133a316f0a7 (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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