SOLICITATION NOTICE
66 -- Purchase of a Zeiss LSM 880 with Airyscan Super Resolution Microscope System and 2 -photon Confocal Imaging
- Notice Date
- 6/1/2015
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- N02RC52585-83
- Archive Date
- 7/2/2015
- Point of Contact
- Gwennifer K. Epps, Phone: 240-276-5445, Terry Galloway, Phone: 240-276-5384
- E-Mail Address
-
eppsg@mail.nih.gov, gallowaytl@mail.nih.gov
(eppsg@mail.nih.gov, gallowaytl@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The National Cancer Institute (NCI), Center for Cancer Research (CCR), Laboratory of Cancer Biology and Genetics (LCBG), has the sole source requirement to purchase: one Zeiss LSM 880 with Airyscan Super resolution microscope system with 2-photon Confocal Imaging, Piezo Scanning Stage, Incubator XL for super resolution Airyscan; Correlative Microscopy holder and software with ZEN Module Shuttle and Find, Stage-top incubation system, PC computer, 30" monitor, and ZEN 2012 software,, from Carl Zeiss Microscopy, LLC, One Zeiss Drive, Thornwood, NY 10594. This acquisition will be processed under FAR Part 12 - Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1 (b)(2) and 13.501-(a)(1) using simplified acquisition procedures for commercial acquisitions. The Government contemplates only one award and will be made as a result of this solicitation. In which the delivery date shall be within 90 days from the date of award. This will be awarded as a firm fixed price type contract. The Associated North America Industry Classification Code (NAICS) 334516 with the applicable business size standard of 500 employees. It has been determined there are no opportunities to acquire green products or services for this procurement. The Laboratory of Cancer Biology and Genetics (LCBG) develops and correlates novel protocols in molecular diagnostics for human and animal tissues, and in noninvasive medical imaging for animal models. Emanating from NCI studies are new therapeutic combinations for targeted cancers now in clinical trials. This purchase will provide for the supply and on-site installation in the Center for Cancer Research (CCR), Confocal Microscopy Core Facility. Hence, NCI is proposing to purchase the following microscope parts as open market from Carl Zeiss: the Zeiss LSM 880 with Airyscan Super Resolution and 2-photon Confocal Imaging with 34 Channel Spectral Detection includes 5 laser lines (458, 488, 514, 561 and 633 as well as 405 and 594.) This Zeiss 880 Airyscan confocal microscope is needed to meet the demand for fast, sensitive, Super Resolution imaging, extended time lapse imaging (overnight), and to provide GAaSP spectral detector for greater sensitivity of low level fluorescent samples. A sole source is intended for this order, based on the facts the Zeiss LSM 880 Airyscan Super Resolution Microscope System and 2-photon Confocal Imaging has unique features not available from other known companies, is compatible with existing equipment such as the pre-existing Coherent Chameleon IR laser, and will potentially yield additional savings to the laboratory and NCI in the future. Carl Zeiss Microscopy is uniquely qualified to provide this equipment. Unique features of The Zeiss LSM 880 Airyscan Super Resolution Microscope System and 2-photon Confocal Imaging system are: 1.ACR - Automatic Component Recognition for filter Sets Ease of operation and integration for flexibility to accommodate multiple filter cubes essential for the wide variety of dyes. Microscope automatically recognizes and fully populates into the software by slipping in the new turret with cubes already loaded. Turrets are easily exchanged with the entire microscope powered on. 2.Stand accommodates both an Airyscan module as well as confocal scanhead. Allows users to image confocally and switch over to Airyscan on the same field of view quickly and easily once regions of interest have been identified. 3.Direct visualization of fluorescence through standard eyepieces integrated into the imaging inverted microscope stand. Critical for the core facility, this instrument is equipped to allow for direct visualization of samples to quickly and easily find areas of interest for scanning allowing users to minimize time for searching for appropriate regions for imaging. 4.Motorized integrated Z focus with a step size of 10nm and travel range of 25mm (GSA) 5.High resolution scanning stage with joystick and integrated computer control including universal specimen holder suitable for variety of slide and round dishes up to 60mm with 5µ reproducibility over the full travel range. 6.The Airyscan as well as the Confocal system must be able to accommodate the following objective lenses: both NA and Working Distances are critical for high resolution samples to be imaged on the microscope. •Plan-Apochromat 40x/1.4 NA >=130 micron WD Oil immersion DIC (SR-SIM/Epi) which is already existing at our facilily. •Plan-Apochromat 63x/1.4>=170 micron WD Oil immersion DIC (SR-SIM/Epi) supplied on the system. •Plan-Apochromat 100x/1.57 Hi-Oil Immersion DIC (SR-SIM/Epi/PALM/TIRF) for possible future upgrade. 7.Airyscan detection unit consists of a calibrated 32-element Gallium Arsenide Phosphide (GaAsP) PMT with typical QE >45 % (peak) and adjustable zoom optics (to accommodate different objectives). The 32-element proprietary area detector is arranged in a compound eye fashion where the central element is adjusted to lie on the optical axis. The Airyscan detector is operated in three different modes: superresolution, variable pinhole and standard confocal. The adjustable zoom optics always ensure that a defined amount of light (1.25 airy units for superresolution and confocal mode & 3.5 airy units for variable pinhole) is projected onto the detector. 8.In super resolution mode the Airyscan detector system achieves images with spatial resolutions of 140nm in x-y and 400nm in z when utilizing 488nm excitation and a 63x 1.4 NA Plan-Apochromat objective. Additionally, the system provides a real-time preview of the super resolution image while data is being acquired. 9.Airyscan provides a 1.7x isotropic increase in resolution in x,y and z with a 4X increase in S/N. 10.System must include full Environmental incubation system that includes heating and CO2 to maintain optimal live cell conditions for multi day experiments. Fully integrated control units into microscope stand control vial TFT. (GSA) 11. Confocal must be able to easily accommodate the pre-existing Coherent Chameleon IR laser for 2-photon imaging. This is not a solicitation for competitive quotations. However, if any interested party especially a small business, believes they can meet the above requirement, may submit a quote and statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. All questions, quote, and the capability statement must be received electronically (via email) to Ms. Gwennifer Epps, Contracting Officer, at ge50d@nih.gov in MS Word or Adobe Portable Document Format (PDF)by June 17, 2015 no later than 11:00 AM EST. No telephone calls or facsimiles will be accepted. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA), through sam.gov. No collect calls will be accepted. Please reference solicitation number N02RC52585-83 on all correspondence.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/N02RC52585-83/listing.html)
- Place of Performance
- Address: National Cancer Institute, NIH, Bethesda, Maryland, 20814, United States
- Zip Code: 20814
- Zip Code: 20814
- Record
- SN03749158-W 20150603/150601235545-8cf009d48d07b203257abf98ceb68aec (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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