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FBO DAILY - FEDBIZOPPS ISSUE OF DECEMBER 24, 2014 FBO #4778
SOLICITATION NOTICE

B -- Macrogen DNA Sequencing Service Per Reaction

Notice Date
12/22/2014
 
Notice Type
Presolicitation
 
NAICS
541711 — Research and Development in Biotechnology
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
 
ZIP Code
20892-7902
 
Solicitation Number
NIH-HHS-NHLBI-CSB-(HG)-2015-046-DLM
 
Archive Date
1/15/2015
 
Point of Contact
Dorothy Maxwell, Phone: 301-435-0352
 
E-Mail Address
maxwelld@mail.nih.gov
(maxwelld@mail.nih.gov)
 
Small Business Set-Aside
N/A
 
Description
THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR A PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institute of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) on behalf of the National Human Genome Research Institute, (NHGRI), intends to negotiate and award a purchase order on a noncompetitive sole source basis to Macrogen Corporation, 1330 Piccard Drive, Suite 205, Rockville, Maryland 20850 to procure the following for NHGRI Undiagnosed Disease Program (UDP): Procurement: This is a Follow-On Requirement. 1. DNA Sequencing Service Per Reaction, Item Number: FS001, Quantity: Number of UDP Samples will be provided upon award. 2. DNA Sequencing service per Plate (96-Well), Item Number: FS003, Quantity Number: UDP Samples will be provided upon award. Background: The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency conducting and supporting medical discoveries that improve people's health and save lives. The National Human Genome Research Institute (NHGRI), National Institutes of Health Undiagnosed Disease Program (UDP) is a trans-National Institute of Health (NIH) initiative that focuses on the most puzzling medical cases referred to the NIH Clinical Center in Bethesda, MD. Many medical specialties from other NIH research centers and institutes contribute the expertise needed to conduct the program, including endocrinology, immunology, oncology, dermatology, dentistry, cardiology and genetics, among the dozens of participating senior attending physicians. A longstanding medical condition that eludes diagnosis by a referring physician can be considered undiagnosed and may be of interest to this clinical research program. Objectives: The NIH UDP uses an innovative paradigm for selecting patients (based upon potential for representing a new disease), for phenotyping (extensive multidisciplinary investigations at no cost to the patient), performing genetic studies (combined SNP and WES analysis using family members and filtering programs developed in house). Specific areas of interest include techniques for studying dominant inheritance and identifying families that are most likely to generate verifiable sequence variants as a result of NGS applied as an agnostic, diagnostic screen for genetic disease. Sequence variants identified by NGS are verified by Sanger sequencing following PCR amplification of the regions predicted by NGS to contain said variants. Based on the reagent, maintenance and personnel costs for in house sequencing, the UDP laboratory contracts out the Sanger sequencing of said PCR products to achieve economies of scale and maintain high quality results. Period of Performance: Base Year: December 2014 through June 2015 Option 1: June 2015 through September 2015 Option 2: October 2015 through September 2016 Justification: Macrogen Corporation has been providing sequencing service for the Undiagnosed Diseases Laboratory for the past two years. Macrogen offers same day free pick up from the laboratory, a 24-hour turnaround time for results, and high quality data return. It is necessary for the Undiagnosed Disease Laboratory to retain the sequencing service provided by Macrogen in order to maintain experimental consistency and to avoid delays incurred by re- optimization of experimental design, bioinformatics testing and redesign, and restructuring the laboratory database that is already in use. The quality of the responsiveness and quality of the service that Macrogen continues to provide to NHGRI/UDP continues to be excellent. Regulatory Authority: This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b) Soliciting from a single source, only one responsible source and no other supplies or services will satisfy agency requirements. Additional Information: Industry Classification (NAICS) Code is 541711, Research and Development in Biotechnology, with a business size standard of 500. The acquisition is being conducted under FAR Part 13, simplified acquisition procedures, therefore the requirements of FAR Part 6 B Competitive Requirements are not applicable (FAR Part 6.001). The resultant Contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-79 (December 15, 2014). This requirement is under the SAT of $150,000.00. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by December 31, 2014 and must reference synopsis number HHS-NIH-NHLBI-CSB-(HG)-2015-046-DLM, may be submitted to the National, Heart, Lung and Blood Institute, Office of Acquisition, COAC Services Branch, 6701 Rockledge Drive, Suite 6149, Bethesda, Maryland 20892-7902, Attention: Dorothy Maxwell. Response may be submitted electronically to maxwelld@mail.nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."
 
Web Link
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NIH-HHS-NHLBI-CSB-(HG)-2015-046-DLM/listing.html)
 
Record
SN03602568-W 20141224/141222234511-00802256090ab52f3dc1989d2672907a (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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