SOLICITATION NOTICE
A -- Lung Tissue Research Consortium - Tissue Repository
- Notice Date
- 11/19/2014
- Notice Type
- Presolicitation
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- NHLBI-HR-16-05
- Archive Date
- 12/16/2015
- Point of Contact
- Sarah Bank, Phone: 3014352158, Scott A Bredow, Phone: (301) 435-0333
- E-Mail Address
-
Sarah.bank@nih.gov, bredows@mail.nih.gov
(Sarah.bank@nih.gov, bredows@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Pre-Solicitation Notice NHLBI Lung Tissue Research Consortium (LTRC) Tissue Repository The National Heart, Lung, and Blood Institute (NHLBI) is seeking a Tissue Repository (TR) for a four year program, the NHLBI Lung Tissue Research Consortium (LTRC). The purpose of this announcement is to provide a Presolicitation Notice for the release of Solicitation NHLBI-HR-16-05. THIS IS A SYNOPSIS. THIS IS NOT A SOLICITATION. The NHLBI is seeking an organization with the ability to serve as the Tissue Repository (TR) for a four-year renewal of the NHLBI Lung Tissue Research Consortium (LTRC). The LTRC is a network of centers cooperating to harvest and process lung tissue specimens for use in scientific studies of the etiology and pathogenesis of lung diseases, especially chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis. The LTRC prepares collections of specimens, linked to clinical data describing the donor subjects, for widespread distribution to investigators for use in their research. The TR will process and store biospecimens, perform histopathological analyses of lung tissues, and prepare biospecimen collections for distribution to external investigators. The TR will operate in cooperation with a Data Coordinating Center which provides overall management, oversight, and administrative support for the LTRC; a Radiology Center that analyses and archives x-ray CT images; and 3-4 Clinical Centers that recruit and characterize human subjects and harvest surgical waste lung tissues. It is expected that the TR will be an institution that routinely performs diagnostic evaluations of surgical lung specimens, is experienced in operation of a biospecimen repository, and has expertise in histopathological research on interstitial lung diseases and chronic obstructive pulmonary disease. The TR is expected to provide the necessary technical expertise and facilities to effectively perform the tasks and meet the requirements identified below: 1. Obtain and maintain Institutional Review Board (IRB) approval for TR activities described in the LTRC Protocol Manual, and any amendments thereto. 2. Provide one member of the Steering Committee (SC) with expertise in lung histopathology who will participate fully in the activities of the SC. 3. Conduct a training course for LTRC Clinical Center (CC) personnel involved in specimen handling and initial processing. 4. Process biological specimens received from LTRC CCs. Perform quality control/quality assurance tests and report results to the LTRC Data Coordinating Center (DCC). 5. Maintain a repository of biospecimens, incorporating specimens collected previously by LTRC. Store specimens received using methods that preserve biospecimen integrity and scientific usefulness. 6. Perform histopathological analyses of lung tissue specimens received to obtain diagnostic and quantitative research measures of disease. Transmit results to the LTRC DCC. 7. Perform diagnostic, light-microscopic, histopathological analyses of lung tissues by a board-certified pathologist. Notify the contributing LTRC CC of any clinically significant abnormalities for relay to the subject's primary care physician. 8. Prepare biological samples and sample collections for distribution to investigators for approved studies as authorized by the NHLBI through the LTRC DCC. 9. Identify any problems with existing LTRC procedures and any difficulties that may interfere with LTRC objectives. Devise strategies to improve procedures and overcome difficulties. 10. Deliver or ship to a repository specified by the NHLBI, all specimens and specimen collections remaining at the end of the contract period, together with the coded information needed to identify each sample by type and donor subject. 11. Develop detailed plans for the creation of an omics data set based on LTRC biospecimens and phenotypic data. Under this solicitation, the Government anticipates award of one (1) Indefinite Delivery, Indefinite Quantity (IDIQ) contract with cost reimbursement task orders for a period of approximately four years with an estimated award date of December 16, 2015. This is not a Request for Proposal (RFP) and the Government is not committed to award a contract pursuant to this announcement. The RFP will be available on the FedBizOpps Web page at www.fbo.gov on or about December 18, 2014.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-HR-16-05/listing.html)
- Place of Performance
- Address: Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Office of Acquisitions, 6701 Rockledge Drive RKL2/6016 MSC 7902, Bethesda, Maryland, 20892-7902, United States
- Zip Code: 20892-7902
- Zip Code: 20892-7902
- Record
- SN03577294-W 20141121/141119234726-8136667262690380a9da95a6a65740dd (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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