MODIFICATION
B -- Antipsychotic and Stimulat Prescribing Patterns in Specific Patient Populations
- Notice Date
- 9/12/2014
- Notice Type
- Modification/Amendment
- NAICS
- 611310
— Colleges, Universities, and Professional Schools
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA(SSSA)-NOI-14-666
- Archive Date
- 10/6/2014
- Point of Contact
- Paul C. Marsalese,
- E-Mail Address
-
paul.marsalese@nih.gov
(paul.marsalese@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- INTRODUCTION This is a pre-solicitation non-competitive (notice of intent) synopsis to award a contract without providing for full or open competition (including brand-name). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institute on Drug Abuse (NIDA), Consolidated Station Support and Simplified Acquisitions (CSS/SA) Branch intends to negotiate and award a purchase order to Trustees of Columbia University in the City of New York. The purpose of this purchase order will be to provide the National Institute of Mental Health (NIMH) with a contractor who whall provide analysis on prescription patterns in the United States of antipsychotic medications in children ranging from one (1) to seventeen (17) years of age; stimulant medications in individuals ranging from one (1) to eighty (80) years of age; and of antipsychotic medications in adults ranging from fifty (50) to eighty (80) years of age. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 611310 with a Size Standard of $25.5M. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-76 dated July 15, 2014 STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source and is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements. BACKGROUND INFORMATION The National Institute of Mental Health (NIMH) has a long-standing interest in psychotropic medication prescribing patterns in the outpatient mental healthcare setting. Analyses performed to date have been limited to data from single states, individual payers, or specific treatment settings as well as surveys with small numbers of treated individuals. Investigators at Columbia University and Yale have a license with Intercontinental Marketing Services (IMS) Health-LifeLink TM for access to the proprietary LRx Longitudinal Prescription 2006-2009 databases for prescriptions from 33,000 retailers (approximately 75% of all retail pharmacies in the US). These databases contain de-identified individual prescriptions that are nationally representative with respect to patient sex, age, and insurance coverage. It is from these databases that the Contractor shall perform a set of analyses. PURPOSE AND OBJECTIVES FOR THE ACQUISITION The Contractor shall provide panalyses on prescription patterns in the United States of antipsychotic medications in children ranging from one (1) to seventeen (17) years of age; stimulant medications in individuals ranging from one (1) to eighty (80) years of age; and of antipsychotic medications in adults ranging from fifty (50) to eighty (80) years of age. CONTRACTOR REQUIREMENTS The Contractor shall: Work with available population-based administrative data from source described in this Notice of Intent on psychotropic prescription drug claims, including data on antipsychotic medications and stimulant medications. Prescription-level data shall be indexable at the patient level and at the prescriber level. Data shall cover at least, but not limited to, calendar years 2006 to 2009 in the United States. The data shall be representative of the corresponding US population; and the database(s) shall be sufficiently large to support rigorous statistical analyses for both males and females and across relevant age ranges (e.g., children, adolescents, older adults). ‘Rigorous' is defined as sufficiently large to have at least 80% power for detecting differences in prescription drug use of 0.5 percentage points or smaller between population cells defined by sex and single year of age. Conduct specific empirical analyses of the prevalence and correlates of psychotropic drug use, by demographic status and across time, as described in further detail in Tasks, listed below. Task 1 - Analysis of Antipsychotic Treatment of Children in the United States The Contractor shall compare antipsychotic use in the United States in recent years, across three (3) age groups - young children (one (1) to six (6) years), children (seven (7) to twelve (12) years), and adolescents (thirteen (13)to seventeen (17) years). The Contractor shall assess the percentage of each age group who received any antipsychotic medication during the course of one year. Rates of antipsychotic use shall be examined separately for males and females and described with respect to duration and dosage of antipsychotic treatment, other co-prescribed classes of psychotropic medications, and in terms of which type of physician (i.e., psychiatrists vs. others) who prescribed the medications. For those patients filling antipsychotic medications for whom service claims data are available, the three age groups shall be further characterized with respect to ten (10) different categories of mental disorders: 1) Schizophrenia and other psychoses 2)Pervasive developmental disorders or mental retardation 3)Bipolar disorder 4)Disruptive behavior disorders 5)Attention deficit/hyperactivity disorder 6)Depression or mood disorder, not otherwise specified 7)Anxiety disorders 8)Adjustment disorder 9)Communication and learning disorders 10)Other mental disorders The results shall provide the first national portrait of antipsychotic use by young children, children, and adolescents in the United States. New insights will be generated concerning how the use of antipsychotic medications changes throughout childhood and adolescence in the United States. Task 2 - National Patterns in Stimulant Treatment The Contractor shall examine the use of stimulant medications - which are principally used to treat attention deficit and hyperactivity disorder (ADHD) - across the life cycle in the United States. The Contractor shall compare the rate and pattern of stimulant use in young children (one (1) to six (6) years), children (seven (7) to twelve (12) years), adolescents (thirteen (13) to seventeen (17) years), young adults (eighteen (18) to twenty-nine (29) years), adults twenty(20) to forty-nine (49) years), and older adults (fifty (50) to eighty (80) years). The six (6) age groups shall be compared with respect to the rate of stimulant use overall and by gender and prescribing physician specialty. Among individuals who are prescribed stimulants, the age groups shall be compared with respect to the total duration of stimulant treatment during the study year. To characterize the duration of stimulant treatment episodes, a related analysis shall examine continuity of stimulant treatment among patients who initiate stimulants during the first quarter of the study year. To evaluate the complexity of their pharmacological treatment, the Contractor shall also examine the proportion of stimulant treated patients in each age group who receive antipsychotics, antidepressants, anxiolytics, and mood stabilizers during the course of the study year. Among the subset of individuals with available service claims data, the Contractor shall compare the six stimulant-treated groups with respect to the proportion who received a diagnosis for ADHD, narcolepsy, depression, cognitive impairment, and obesity. The results shall describe stimulant prescribing practices across the lifespan and help to identify patient groups at risk for suboptimal stimulant treatment. Task 3 - Antipsychotic Treatment of Older Adults in the United States The Contractor shall examine patterns of antipsychotic treatment among older adults in the United States. The Contractor will compare the rates at which adts aged fifty-one (51) to sixty (60), sixty-one (61) to seventy (70), and seventy-one (71) to eighty (80) years of age receive any antipsychotic medications during the study year, and antipsychotic treatment rates among males and females within these three (3) age groups. Among adults treated with antipsychotic medications, the Contractor shall compare the three age groups with respect to the mean number of days of antipsychotic medication treatment during the study year, mean chlorpromazine equivalents prescribes during days of treatment, total antipsychotic exposure during the study year, and treatment with individual antipsychotic medications. Among those antipsychotic-treated patients for whom service claims data are available, the Contractor shall compare the three age groups with respect to the percentage who receive a diagnosis of dementia, depression, anxiety, delirium, bipolar, and schizophrenia or related psychoses. The Contractor shall also determine the proportion of patients whose antipsychotic medications are prescribed by psychiatrists as compared with non- psychiatrist physicians focusing on provider specialty differences in medication selection, dose, duration of treatment, and treated conditions. The results shall offer new insights into national antipsychotic medication treatment of older adults. CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATION The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, Trustees of Columbia University in the City of New York is the only vendor in the current market place that can provide the services required by the National Instute of Mental Health. In accordance with FAR part 10, extensive market research was conducted to reach this determination. Specifically, a small business sources sought notice was posted to FedBizOpps referencing the above detailed generic requirements and no responses were received. Additionally, knowledgeable inviduals in the Government and Industry were contacted for market research purposes. None of the subject matter experts contacted were able to identify any contractor other than Trustees of Columbia University in the City of New York could meet the needs of this requirement. Finally, a review of both the GSA Advantage and Dynamic Small Business Search returned no results. Therefore, only Trustees of Columbia University in the City of New York is the only vendor capable of meeting the needs of this requirement. The intended source is: Trustees of Columbia University in the City of New York 630 W 168th Street, Floor 4 New York, NY 10032-3725 Stanford, CA 94305-2004 APPLICABLE CLAUSES AND PROVISIONS The provision at FAR clause 52.213-4, Terms and Conditions - Simplified Acquisiton (Other Than Commercial Items). The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. CLOSING STATEMENT THIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by the closing date and time of this announcement and must reference the solicitation number. Responses may be submitted electronically to Paul Marsalese, Contract Specialist, at paul.marsalese@nih.gov. US Mail and Fax responses will not be accepted.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA(SSSA)-NOI-14-666/listing.html)
- Place of Performance
- Address: Rockville, Maryland, 20852, United States
- Zip Code: 20852
- Zip Code: 20852
- Record
- SN03509842-W 20140914/140913000504-ee14496a1cca8e0f742fe88cbbe3e24e (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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