SOLICITATION NOTICE
66 -- Upgrade of a Cell/Embryo Micromanipulation/Microinjection System for a Zeiss Axiovert 200 Optical Microscope - SOW
- Notice Date
- 9/8/2014
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-(SSSA)-14-686
- Archive Date
- 10/3/2014
- Point of Contact
- Andriani Buck, Phone: 3014021677
- E-Mail Address
-
andriani.buck@nih.gov
(andriani.buck@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Statement of Work This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is HHS-NIH-NIDA-(SSSA)-14-686 and the solicitation is issued as a request for quotation (RFQ). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Test Program for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2005-76 effective August 25, 2014. This acquisition is unrestricted. The associated NAICS code 334516 and the small business size standard 500. STATEMENT OF OBJECTIVES The Cerebral Microcirculation Section of the Laboratory of Functional and Molecular Imaging (LFMI) has recently become interested in developing techniques to produce transgenic marmosets as a way to advance its research of brain function and neurological disorders. This purchase will provide for the upgrade of an existing cell/embryo micromanipulation and microinjection rig that currently equips an also existing inverted optical microscope, model Carl Zeiss Axiovert 200, S/N 205199, NIH property number 01479587, for the purpose of enabling in vitro micromanipulation and microinjection of individual cells and embryos. Title: Upgrade of a Cell/Embryo Micromanipulation/Microinjection System for a Zeiss Axiovert 200 Optical Microscope STATEMENT OF WORK The Cerebral Microcirculation Section of the Laboratory of Functional and Molecular Imaging (LFMI) has recently become interested in developing techniques to produce transgenic marmosets as a way to advance its research of brain function and neurological disorders. To produce transgenic marmosets, embryos collected from donor females must be manipulated and injected with lentiviruses containing the transgene of interest. This technique, called Embryonic Microinjection (MI), is performed using an existing inverted microscope. To enable precise and successful manipulation of the embryos, the microscope is equipped with a micromanipulator/microinjection system (rig). This system is composed of two micromanipulators that allow precise 3D positioning of micropipettes to physically interact with the cells/embryos under the microscope, with a level of precision of movement that cannot be attained by the unaided human hand. One of the micromanipulators is used to gently hold the cell/embryo of interest, while the other micromanipulator holds a microcapillary needle containing the lentiviruses to be injected into the cell/embryo. In addition, the system also has a manually controlled microinjector, operated by pressurized air, for pressure control, manual microinjection and liquid dispensing; and an electronic microinjector, to provide precise control of the injection pressure and volume. The Cerebral Microcirculation Section currently has an inverted microscope, model Axiovert 200, S/N 205199, NIH property decal 01479587, that is equipped with an outdated micromanipulator/ microinjector rig manufactured by EppendorfNorth America, Inc. that cannot further support the operation needs of our group. This rig needs to be upgraded to the latest available version so that use and operation of our MI experiments can continue. The present project is aimed at upgrading the existing micromanipulation/microinjection rig with a new equivalent system. A micromanipulator/microinjection system to allow embryos to be manipulated and injected in vitro is needed. This system must be composed of: a. Two (2) micromanipulators that allow precise 3D positioning of micropipettes to physically interact with the cells/embryos under the microscope, with a level of precision of movement that cannot be attained by the unaided human hand. One of the micromanipulators is used to gently hold the cell/embryo of interest, while the other micromanipulator holds a microcapillary needle containing the lentiviruses to be injected into the cell/embryo. b. One (1) manually controlled microinjector, operated by pressurized air, for pressure control, manual microinjection and liquid dispensing. c. One (1) electronic microinjector, to provide precise control of the injection pressure and volume. d. One (1) stage adapter for the existing inverted optical microscope, model Carl Zeiss Axiovert 200. The system will replace an existing micromanipulation/microinjection rig that equips and existing microscope. Therefore, the system to be purchased must be compatible with the existing microscope. Deliverables A micromanipulator/microinjection system composed of 2 micromanipulators, 1 manually controlled microinjector, 1 electronic microinjector, and 1 stage adapter. Documentation on the system's operation and maintenance, and related parts list. Warranty and service information. Acceptance Final acceptance shall be upon the successful installation and operation of the above specified equipment, and upon the successful completion of the owner/end user staff training. Please refer to the attached Statement of Work for further detail, specifications, and evaluation criteria. FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. Offerors must include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, with its offer. FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. FAR clause 52.212.-2, Evaluation - Commercial Items, is applicable to this requirement. Offers will be evaluated on (1) the capability of the system quoted and whether it meets the essential features as specified in the statement of work; (2) the government's desired delivery date of 30 days after receipt of order; and (3) price. FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses must be received by September 18, 2014, 8:00 am EST and must reference number HHS-NIH-NIDA-(SSSA)-14-686. Responses may be submitted electronically to andriani.buck@nih.gov or by U.S. mail to the National Institute of Drug Abuse (NIDA), Station Support / Simplified Acquisition Branch (SS/SA), 31 Center Drive, Building 31, Room 1B59, Bethesda, Maryland 20892-2080, Attention: Andriani Buck. Fax responses will be accepted at (301) 480-1358. Contact Andriani Buck at 301-402-1677 for information regarding the solicitation.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA-(SSSA)-14-686/listing.html)
- Place of Performance
- Address: National Institutes of Health, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN03500315-W 20140910/140909022140-490e3379e8ac0fbaea250f89f2b54838 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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