SOLICITATION NOTICE
B -- Interactive Risk Charts by Smoking Status
- Notice Date
- 8/11/2014
- Notice Type
- Presolicitation
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Bldg 1050, Frederick, Maryland, 21702, United States
- ZIP Code
- 21702
- Solicitation Number
- N02PC42634-57
- Archive Date
- 9/9/2014
- Point of Contact
- Reyes Rodriguez, Phone: 240-276-5442, Terry L. Galloway, Phone: 240-276-5384
- E-Mail Address
-
reyes.rodriguez@nih.gov, gallowaytl@mail.nih.gov
(reyes.rodriguez@nih.gov, gallowaytl@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- National Cancer Institute (NCI), Division of Cancer Control and Population Sciences (DCCPS), Statistical Methodology and Applications Branch (SMAB), plans to procure on a sole source basis services to explore methods to develop risk estimates of dying of smoking related causes of death by smoking status from Informulary, Inc., 16 Cavendish Road, Lebanon, New Hampshire 03766. This acquisition will be processed in accordance with simplified acquisition procedures as stated in FAR Part 13.106-1(b)(1). The North American Industry Classification System code is 541990 and the business size standard is $14.0 Million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. The period of performance is twelve (12) months from date of award. It has been determined there are no opportunities to acquire green products or services for this procurement. NCI/DCCPS/SMAB serves as the most authoritative source of information on cancer incidence, prevalence, mortality, and survival in the United States. Recently staff at NCI in collaboration with Drs. Steven Woloshin and Lisa Schwartz completed an interactive web site called "Know Your Risks: Interactive Risk Charts to Put Cancer in Context". This website is undergoing final NCI review before it is publically launched. This website is based on earlier work by Drs. Woloshin and Schwartz (JNCI 2002, 2008, and University of California Press, 2008). Drs. Woloshin and Schwartz indicated that to make sense of the disease risks they face, people need basic facts about the magnitude of a particular risk and how one risk compares with other risks. Unfortunately, this fundamental information is not readily available to patients or physicians. They created simple static one-page charts that present the 10-year chance of dying from various causes. There was recognition that these static risk charts could be greatly enhanced by harnessing the power of the web to produce interactive risk charts. The website can produce four types of charts: (1) Big Picture Charts which are similar to the static charts developed in the JNCI articles; (2) Custom Charts which allows the user to customize the causes of death and time horizon for the risks; (3) Your Chances Charts which allows the user to rank the causes of death for a specific age, race, and gender, and to compare the risks when the person was 10 years younger, and when the person will be 10 years older; and (4) Special Cancer Tables which present the risk of diagnosis and death for cancers in the time frame selected. The Contractor shall: • Explore the advantages and disadvantages of various approaches for developing the proposed estimates. Two basic approaches can be explored: (1) an attributable risk approach in which age-specific estimates of the relative risk of death by smoking status are paired with age-specific prevalence of smoking status are combined to partition US mortality estimates by smoking status, and (2) an absolute risk approach in which a single data source is used to develop the estimates. • Explore various data sources for developing the proposed estimates. For the attributable risk approach possible data sources for the relative risks are: the American Cancer Societies Cancer Prevention Studies (CPS), the National Health and Nutrition Surveys (NHANES) mortality follow-up, the Tobacco Use Supplement to the Current Population Surveys (CPS-TUS), the National Health Interview Survey (NHIS) mortality follow-up, National Institutes of Health-American Association of Retired Persons Diet and Health Study (NIH-AARP), the Women's Health Initiative (WHI), and the Health Professionals Follow-up Study (HPFS). Possible data sources for population-based estimates of smoking prevalence are NHIS and CPS-TUS. For the absolute risk approach, there is probably only one possible data source, NHIS surveys with mortality follow-up. • Explore possible ways to partition the population by smoking status. Possibilities include current, former, and never smokers. Possible extensions include partitioning current smokers by pack-years or current cigarettes per day; former smokers by pack -years and years since quitting. For former smokers, person years at risk need to account for the fact that recent ex-smokers may relapse after the survey date. For current smokers, person years at risk need to be right censored to account for the fact that they may quit after the survey data. • Explore the possible length of possible follow-up for risk estimates, e.g. 5 year, 10 year, remaining lifetime. • Explore possible statistical methods for developing the estimates. Possibilities for relative risk estimates include direct estimates, Poisson regression methods, or survival methods. Possibilities for prevalence estimates include direct estimates, or multiple logistic regression. The primary methods to estimate the absolute risk approach is a competing risk left truncated survival methods, although other possibilities can be explored. • Develop preliminary estimates of the components necessary to develop the estimates. The founders of Informulary have conducted the seminal work in the area of risk charts, and have worked with the NCI to develop interactive risk charts. They have unique knowledge and experience in the development and dissemination of these charts. Any efforts to identify the required skills and expertise through outside sources would pose additional costs to the government, delays in the project, and potentially risking the outcome of this project. Therefore, in the best interest of the government, this contract should be awarded to Informulary, Inc. This notice is not a request for competitive quotation. However, if any interested party, especially small business believes it can meet the above requirement, it may submit a proposal or quote for the Government to consider. The response and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Responses must be received in the contracting office by 11 AM EST, on August 25, 2014. All responses and questions must be in writing and faxed 240-276-5399 or emailed to Reyes Rodriguez, Contracting Specialist via electronic mail at reyes.rodriguez@nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through sam.gov. Reference: N02PC42634-57 on all correspondence.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/FCRF/N02PC42634-57/listing.html)
- Place of Performance
- Address: Contractor's Site, United States
- Record
- SN03460555-W 20140813/140811235806-074138c03e709de100ea117768e6b1e5 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |