SOURCES SOUGHT
B -- Whole Genome Methylation Profiling and RNA Sequencing in Sex Chromosome Aneuploidy
- Notice Date
- 7/30/2014
- Notice Type
- Sources Sought
- NAICS
- 621511
— Medical Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SBSS-FY14-519
- Archive Date
- 8/21/2014
- Point of Contact
- Paul C. Marsalese, Phone: 3015941971
- E-Mail Address
-
paul.marsalese@nih.gov
(paul.marsalese@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, MD 20892. Introduction: This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. North American Industry Classification System (NAICS) CODE: The NAICS code applicable to this requirement is 621511 - Genetic testing laboratories - and the associated small business size standard of $30.0 million dollars. Background Information: This potential requirement involves characterization of DNA methylation and gene expression in a large, rare, cohort of individuals with altered sex chromosome count, which has been accrued over the last decade by the NIMH Intramural Research Program Child Psychiatry Branch. This cohort has been studied in terms of behavioral and neuroanatomical profiles: the addition of genomic profiling will be critical in unraveling the potential molecular mechanisms underlying clinical features of SCA. Thus far, a pilot survey has been conducted on gene-expression, using the Illumina BeadArray platform. This has identified dramatic changes in gene expression, which now needs to be followed-up on by profiling DNA methylation and getting a more comprehensive picture of expression changes using RNAseq technology Purpose and Objectives for the Acquisition: The National Institute of Mental Health Child Psychiatry Branch potentially requires whole genome methylation and RNA sequencing services for an ongoing project examining the consequences of abnormal sex chromosome count on genome functioning. Project requirements: Illumina 450K chip-based whole genome methylation measures and single read RNAseq data for gene-wise expression profiling, in 100 paired samples of lymphoblastoid cell-line derived DNA and RNA (respectively). Anticipated period of performance: It is anticipated that the period of performance for this requirement will be four (4) months from date of award. Capability Statement: Contractors that believe they possess the ability to provide the required services and resources should submit documentation of their ability to meet each of the project requirements to the Contract Specialist. Contractors must provide their Company Name, DUNS number, Physical Address, and Point of Contact Information. Capability Statement: Contractors that believe they possess the ability to provide the required product should submit documentation of their ability to meet the project requirements to the Contract Specialist. Contractors should also provide their Company Name, DUNS number, Physical Address, and Point of Contact Information. Interested organizations are required to identify their type of business, applicable North American Industry Classification Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non responsive. When submitting this information, please reference the solicitation notice number. All capability statements sent in response to this Sources Sought Notice must be submitted electronically (via email) to Paul Marsalese, Contract Specialist, at Paul.Marsalese@nih.gov in MS Word format within 7 calendar days of the date of this announcement. All responses must be received by the specified due date and time in order to be considered. Concluding Statement: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. The Government intends to negotiate a fixed price contract.
- Web Link
-
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- Record
- SN03443189-W 20140801/140730235212-ffe74815bfab7e1598520a901f590640 (fbodaily.com)
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