SOURCES SOUGHT
66 -- AVANCE III I-ID(TM) 700 HIGH PERFORMANCE DIGITAL NMR SPECTROMETER
- Notice Date
- 7/24/2014
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, Nat'l Institute of Diabetes, Digestive, & Kidney Diseases, 2 Democracy Plaza, Suite 700W, 6707 Democracy Blvd., MSC 5455, Bethesda, Maryland, 20892-5455
- ZIP Code
- 20892-5455
- Solicitation Number
- NIHLM2014224
- Archive Date
- 8/2/2014
- Point of Contact
- V. Lynn Griffin, Fax: 301-480-8501, MAXWELL KIMPSON,
- E-Mail Address
-
griffinv@mail.nih.gov, Max.Kimpson@nih.gov
(griffinv@mail.nih.gov, Max.Kimpson@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This Small Business Sources Sought Notice is for information and planning purposes only and shall not be construed as a solicitation or as an obligation or commitment by the Government. This notice is intended strictly for Market Research. The National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases is conducting a market survey to determine the availability and technical capability of qualified small business, veteran-owned small business, service-disabled veteran-owned small business or HUBZone small businesses capable of providing following items: Brand Name or Equal to: Bruker Bio-Spin AVANCE III I-ID TM 700 HIGH PERFORMANCE DIGITAL NMR SPECTROMETER with the following specifications: MAGNET/SHIM/LOCK SYSTEM : Compact ASCEND TM Superconducting Magnet System with 5.4 cm bore, (operation field at 16.4416 Tesla) including helium and nitrogen level sensors and magnet stand. Advanced magnet design for very significant reduction of the stray field and reduced cryogen consumption. Incorporates advanced External Disturbance Suppression (EDS TM ) for dramatic reduction of magnetic field perturbations from sources such as subways and electric trains. Magnet pressure and temperature stabilization system. Bruker Smart Magnet System (BSMS TM ) shim and 2G DigiLock TM control, including Digital Frequency Generation, Digital Quadrature Receiver, computer-controlled lock regulation system and ultra-stable, low current noise Shim Control Boards (SCBs). Bruker Orthogonal Shim System (BOSS TM -3) with 36 low current and low heat dissipation gradient shims. BST (Bruker Sample Transport) upper shim stack. Enables high flow rates for VT gas and includes integral sensors for communication with theBSMS. Set of magnet vibration isolation posts, for reduction of the severe effects of strong floor vibrations. Helium transfer line. STAINLESS STEEL RF CABINET : Two-Bay, 19" rack mounted cabinet with rf shielding and full front access to all sub-assemblies and cabling. AMPLIFIERS & RECEIVER : Enhanced 2G Digital Quadrature Detection Receiver (RXAD/2) with integrated high performance ADCs. Provides very high dynamic range, high digital resolution and large bandwith digital filtering. BLAXH2H500/100/250 transmitter system, including: 1H, 19F transmitter for observe and homo/heteronuclear decoupling, I 00 Watt pulse power with 25 Watt CW, all operations under computer control, X-frequency (6-365 MHz) broadband transmitter system for Xfrequency observe and decoupling; for both CW and high power pulse operations; 500 Watt pulse power with 30 Watt linear CW, all operations under computer control, 2H transmitter for decoupling and gradient shimming, 250 Watt pulse power, all operations under computer control. BLAX500 linear broadband amplifier for X-nucleus pulse and decouple with ultra-fast blanking and rise/fall times; 500 Watt linear pulse power, 30 Watt linear CW, all operations under computer control. FREQUENCY GENERATION, DIGITAL CONTROL & ACQUISITION Timing Controller provides exact timing and full flexibility in data acquisition with 12.5 nsec timing resolution Enhanced RF generation including Signal Generation Unit (SGU/3) for 4 channels, for generation of phase, amplitude, and frequency using Direct Digital Synthesis (DDS) covering a frequency range from 6 to l,OOOMHz. Provides <0.01° phase settability and <0.005 Hz frequency resolution. Digital up conversion at 960MHz. Includes high performance wave form memory for programming of experimental sequences including ultra-fast pulse programming, pulse shaping and composite pulse decoupling executable synchronously or asynchronously. Gradient Controller for simultaneous control of up to three magnetic field gradients with real time generation of gradient shapes. Requires Gradient Amplifier. Digital Receiver Unit (DRU TM ) with integrated high performance digital filters and Digital Quadrature Detection (DQD TM ) that virtually eliminates quad images and spikes and 60 Hz interference in experiments for large sweep widths. PRE-AMPLIFIERS : Multilink TM HPPR/2 preamplifier, including: HPLNA 1H/19F preamplifier; 21-I preamplifier (for lock and 2D observe); HPLNA X-BB preamplifier; 13C preamplifier; 15N preamplifier; Control unit with touch screen graphical display; Built-in tune/match display Linux workstation with the following configuration: Intel Dual Core TM 2.53Gl:-Iz Processor and 16 GB memory. A 24 inch Flat Panel monitor; 1TB Hard Drive; 16X max DVD±RW/CD-RW drive; 2 X LAN I 0/100/1000 ethernet adapters; 104+ Keyboard; Scrolling Mouse, mouse pad; Linux OS; One year manufacturer's warranty on PC. Bruker TopSpin software package is included for acquisition and processing of ID, 2D, 3D and 4D NMR data, including PLOT, ICONNMR, NMR Guide and NMR-SIM. Includes media, on-line hypertext manual and single license. PERIPHERAL DEVICES/USER INTERFACE Table for the workstation/printer is not included (available as an option) Printer for text and spectra is included PROBES AND OTHER FEATURES - CryoProbe TM ultra-high sensitivity NMR probe including: Triple Resonance Inverse Detection TCI CryoProbe TM for observation with 15N and 13C decoupling and 13C observation with 1H and 15N decoupling (5 mm sample diameter), 2H lock channel, Zgradient coil for use with GRASP TM II, GRASP TM II/A, or GRASP TM III accessory., and standard CryoCoupler TM. Sample temperature range 0 to 80°C. Sample Positioning Unit (SPU). Permits use of shaped tubes for minimized sample heating with lossy samples. One (1) Shaped Tube Shuttle for use with Shaped Sample Tubes. GRADIENTS : GRASP TM III three-axis GRAdient SPectroscopy accessory for the A VANCE series. Includes ultra-stable power supply with digital preemphasis adjustment and three channel gradient amplifier (10 Amp per channel), for generation of up to three orthogonal high current gradients. Requires GRASP TM II or GRASP TM III probe with built-in gradient coils. Includes Gradient Controller for simultaneous control of magnetic field gradient channels with real. time generation of gradient shapes. GRADIENT SHIMMING : Deuterium gradient shimming including Deuterium amplifier. VARIABLE TEMPERATURE : Advanced Bruker Smart Variable Temperature (BSVT) control unit, with digital control module. Connects to thermocouple and heater incorporated into Bruker probes. All functions under full computer control. Temperature accuracy± 0.2 'C (with± 1.0 °C room temperature stability), but ±0.01°C within the temperature range of+ 15 to+ 35C. Maximum temperature 200 'c (400 'c with optional BVTB-3500 booster). Note: ceramic sample spinners required for high resolution VT operation. A low temperature accessory is required for operation near or below ambient temperature. BCU-I, pre-cooling and stabilization accessory, for ultra-precise temperature control from near ambient conditions down to 0°C sample temperature. Currently, advances in solid state NMR now make it possible to study details of the molecular structure of fibrillar samples, underlying a host of amyloid diseases. To date, solid state NMR studies of Abeta fibrils and other large, insoluble systems by the NIDDK Solid State NMR and Biological Physics Section have relied on use of a 750 MHz instrument, shared with the solution NMR groups. This limited (33%) access to high field solid-state NMR instrument time is neither sufficient nor efficient for carrying out time-consmning data collections needed to make rapid progress in this important and increasingly time-sensitive research. Purchase of the 3-axis gradient 700 MHz NMR system will make tl1e 750 MHz instnnnent available full-time for solid-state NMR experiments, while offering new advanced capabilities to the solution NMR programs of the Protein NMR and Biophysical NMR Spectroscopy Sections. The intended procurement will be classified under North American Industrial Classification (NAICS) code 334516 with a size standard of 500. Offerors who are capable of providing at a minimum, fifty-one percent (51%) of the required/actual services of this solicitation. All respondents are requested to identify their firm's size and type of business. Interested firms responding to this market survey must provide (a) capability statement demonstrating their experience, skills and capability to fulfill the Government's requirements for the above. The capability statement shall be in sufficient enough detail, but not to exceed 15 pages, so that the Government can determine the experience and capability of your firm to provide the requirements above. Your capability statement, not to exceed 15 pages, should include references. Capability statement must be received at the address identified in this synopsis no later than 11:00 A.M. local time at designated location) on August 1, 2014. Responses by FAX or E-MAIL WILL NOT BE ACCEPTED. This synopsis is for information and planning purposes and is not to be construed as a commitment by the Government, nor will the Government pay for information solicited. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provided feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate response to a solicitation. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)." Any questions regarding this announcement must be sent via email to griffinv@mail.nih.gov and must include solicitation NIHLM2014174 in the subject line of email. PLEASE NOTE: In order to receive an award, contractor must be registered and have valid certification in the System for Award Management (SAM) [formerly CCR].
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDDKD/NIHLM2014224/listing.html)
- Record
- SN03437016-W 20140726/140724235603-822500a0fb09b833953f671941b8eae7 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |