MODIFICATION
A -- Development and Maintenance of an Aged Cell Bank - Draft Statement of Work
- Notice Date
- 7/18/2014
- Notice Type
- Modification/Amendment
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Mental Health, Contracts Management Branch, 6001 Executive Blvd, Rm 8154, MSC 9661, Bethesda, Maryland, 20892-9661
- ZIP Code
- 20892-9661
- Solicitation Number
- HHS-NIH-NIDA(AG)-SBSS-14-001
- Archive Date
- 8/16/2014
- Point of Contact
- Fred Ettehadieh, Phone: 301-443-9154, Yvette Brown, Phone: 301-443-2696
- E-Mail Address
-
fred.ettehadieh@nih.gov, Yvette.Brown@nih.gov
(fred.ettehadieh@nih.gov, Yvette.Brown@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Draft Statement of Work HHS-NIH-NIDA(AG)-RFP-14-001 PRE SOLICITATION NOTICE THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institutes of Health, National Institute on Aging (NIA) intends to negotiate, under authority of Federal Acquisition Regulation (FAR) 6.302-1, on a noncompetitive, sole source basis, with Coriell Institute for Medical Research (Coriell), Camden, New Jersey for the Development and Maintenance of an Aged Cell Bank requirement. The Government will use procedures in FAR Part 15, Contracting by Negotiations. The North American Industry Classification System (NAICS) Code will be 541712 (500 employees). This effort will be for a 12-month base period with four 12-month option periods on or about February 1, 2015. The statutory authority permitting other than full and open competition 41 United States Code (U.S.C.) 253(c)(1) as set forth in FAR 6.302-1. The NIA supports research on the biology of aging and age-related conditions and diseases. The purpose of this requirement is to continue the operation of the Aging Cell Repository which serves as a resource to facilitate biogerontology research by providing high quality, uncontaminated, well-characterized, cell lines to investigators. The importance of this resource lies in the unique collection of cell lines for aging research and the research opportunities they present. The proposed contractor is the only source that meets the needs of the NIA is that there is significant risk in moving such a large collection of cryopreserved cell lines. Support for a noncompetitive, sole source acquisition is based on the risks inherent in moving the aged cell bank and on the past performance of the current contractor. One of the primary requirements for the NIA aged cell bank is high quality cell lines from diverse animal models and human populations. The current bank has been built up over the past forty years to the point where it has many unique and irreplaceable cell lines. The bank has over 2,600 cell lines, which represents over 114,000 individual vials. These vials are stored at three different sites for safety reasons - cells are stored in 63 different liquid nitrogen tanks at the primary site, 11 liquid nitrogen tanks at the on-site back-up facility, and 117 boxes at the off-site back-up facility. There are also over 2,000 buffy coats from 600 subjects in a centenarian study stored in 12 liquid nitrogen tanks, and over 38,000 vials of DNA stored in 12 freezers. It is essential to maintain the quality of the cell lines, and because cryopreserved cell lines are very sensitive to even slight changes in temperature during storage, moving them carries a real risk. Many of the cell lines are irreplaceable and loss of even a portion of the cell lines would set back the research endeavors of the biology of aging research community. The cost to replace those lines for which replacement is possible would be prohibitive. Since inception, approximately $26,000,000 has been invested in the aged cell bank - in today's dollars, replacement would cost many-fold that amount. And the loss of time and therefore valuable research to try to start over would seriously impact aging research productivity. Coriell has been the contractor for this resource since its inception in 1974. Coriell is recognized as a leader in the field of cell repository research and service for biomedical research. Coriell has developed new methodologies to enhance the characterization of the cell lines, which increases their value to the research community. The quality control at all stages of the work scope have been the highest possible and Coriell has worked with the Government and the research community to acquire new cell lines of value to the aging research community. In addition, Coriell pioneered many of the techniques used in biomedical research use of cell cultures, and has provided solutions to problems encountered by researchers. Coriell offers a wide variety of service to the Aged Cell Bank that increase the value of the cell lines, including molecular fingerprinting to confirm identity of the cell lines, genomic and chromosomal analysis, isolation of high-quality DNA and microarrays. They are uniquely positioned to keep the NIA Aged Cell Bank on the cutting edge of research technology, and have implemented new technologies in previous contracts that have characterized the cell lines in-depth, aiding the use of these cell lines in research. Optimal culture conditions are essential to faithfully mirror the biological nature of the cell lines and Coriell is the leader in developing standardized culture conditions based on the needs of each cell line. Millions of dollars of current funded research projects depend on the integrity of the cell lines, and many more millions of dollars of research will build on the findings published from the research using these cell lines. Therefore, it is essential to maintain this cell bank with the leader in the field. Since this is a sole source requirement, the solicitation will not be made available through the Government Point of Entry (GPE). However, the solicitation can be obtained by sending an electronic request (via email) to Fred Ettehadieh at fred.ettehadieh@nih.gov. In return, the requestor will receive a copy of the solicitation in an adobe format. In addition, a draft Statement of Work is attached for further clarification of the requirements of the Aged Cell Bank. No telephone or facsimile responses will be accepted. All requests must be sent no later than 12:00 P.M. (EST) on August 1, 2014. Otherwise, the Government will not be obligated to respond to requests after the above mentioned due date. The proposed acquisition was previously publicized under sources sought notices HHS-NIH-NIDA(AG)-SBSS-14-001 and HHS-NIH-NIDA(AG)-RDSS-14-001.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIMH/HHS-NIH-NIDA(AG)-SBSS-14-001/listing.html)
- Place of Performance
- Address: To be determined., United States
- Record
- SN03430189-W 20140720/140718234719-c6e0cf9514ebbdb867e10b498704943f (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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