SOURCES SOUGHT
66 -- Ethanol Inhalation system
- Notice Date
- 6/26/2014
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA(SSSA)-SBSS-14-356
- Archive Date
- 7/26/2014
- Point of Contact
- Farrin Stanton,
- E-Mail Address
-
farrin.stanton@nih.gov
(farrin.stanton@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- INTRODUCTION This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources, (2) whether they are small businesses; HUBZone small businesses, service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. The notice is strictly for research and information purposes only. The information requested will assist the Government in determining the appropriate acquisition method, including whether a small business social-economic set-aside, competitive or non-competitive method is possible, and to determine the availability of qualified companies technically capable of meeting the Government's requirement. ALL organizations with the capability and availability to perform the requirement under the applicable NAICS code are invited to submit a response to this notice. NORTH AMERICAN CLASSIFICATION SYSTEM (NAICS) CODE 334516 Analytical Laboratory Instrument Manufacturing Background Initially, drug intake is motivated by the pleasant drug effects (positive reinforcement). In the transition to drug dependence, the brain stress systems become sensitized and drug intake is motivated by negative reinforcement mechanisms in which the drug is taken to relief negative emotional states (e.g., anxiety, depression, dysphoria, pain). Therefore, understanding the processes mediating the transition from positive to negative reinforcement in the transition to dependence is critical to develop new methods of prevention, diagnosis and treatment of drug dependence. The vapor chambers setup must be unique to allow us to reliably induce alcohol dependence, which would not be possible with voluntary intake or exposure to low alcohol levels. The blood alcohol levels can be precisely monitored and controlled so that animals are healthy and active. The drug vapor chambers should allow for vaporization of methamphetamine, cocaine, THC, nicotine, etc. The levels of intoxication must also be precisely measured and maintained in a safe range. A practical application of drug vapor chambers is modeling nicotine abuse and dependence. The levels of nicotine exposure have to be controlled in a way to model second hand smoking, mild, moderate and heavy smoking. These features make the alcohol and drug vapor chambers unique to producing different levels of drug intoxication and withdrawal and allowing us to the study different phases of the addiction process for different drugs of abuse. This is important because the burden of disease and disability caused by alcohol, tobacco and other drugs of abuse is enormous. The design of the inhalation chambers have to be designed to perfection to meet the lab needs. This equipment will be used on a daily basis and will be the main equipment in the lab along with operant chambers. PROJECT DESCRIPTION The Custom Inhalation Chamber System must consist of: Custom ethanol inhalation system with six oversized, separate cages that can accommodate three 700 gram rats per chamber, maintaining AALAS space regulations.60 cages included. 100 custom 16 ounce water bottles with caps and sipper tubes included. Custom e-Vape Chamber System. Custom e-Vape system for five addictive inhalants. Includes six standard rat chambers. 24 Cage bottoms included.6 Cage tops included. The Behavioral Neuropharmacology Section uses alcohol and drug inhalation chambers to produce robust models of alcohol and drug dependence. The requirements are: • These chambers must allow us to very precisely control the concentration of alcohol or drug in the air to produce different levels of alcohol/drug exposure to induce a wide range of biological changes to be systematically studied. • Importantly, they must allow intoxication levels to be tightly controlled to preserve animal health. • Must reliably induce alcohol dependence, which would not be possible with voluntary intake or exposure to low alcohol levels. The blood alcohol levels can be precisely monitored and controlled so that animals are healthy and active. • The alcohol and drug inhalation chambers must have a double-chamber containment system that guarantee that the experimenter is safe of any hazardous vapor exposure at all time. Therefore, even if the experimenter forget to close the rat chamber or do it improperly resulting in air leakage the double containment will ensure that the room where the system is, is not contaminated • The alcohol and drug inhalation chambers must have a double exhaust system that provide negative pressure inside the first containment chamber so that no vapor escape the system when the doors are open. Guaranteeing again the safety of the experimenter. Other commercially available system have only 1 exhaust without containment chamber with negative pressure. • Must have carbon activated charcoal in the exhaust line to scrub drug vapors before going into house exhaust • Each chamber must be upgradable to do exposure to electronic cigarettes and methamphetamine, cocaine, THC and heroin vapor • Each chamber must have an integrated sampling system to monitor the concentration of vapor in the air. • Must be IACUC and AAALAC certified. 3 each – Custom Inhalation Chamber System Custom ethanol inhalation system with six oversized, separate cages that can accommodate three 700 gram rats per chamber, maintaining AALAS space regulations. 60 cages included. 100 custom 16 ounce water bottles with caps and sipper tubes included. 1 each – Custom e-Vape Chamber System Custon e-Vape system for five addictive inhalants. Includes six standard rat chambers. 24 Cage bottoms included. 6 Cage tops included. 6 Cage grids included. CAPABILITY STATEMENT /INFORMATION SOUGHT Respondents must provide, as part of their responses, clear and convincing documentation of their capability of providing the item(s) specified in this notice. Contractors that believe they possess the ability to provide the required must submit specific documentation of their ability to meet each of the project requirements to the Contract Specialist. Contractors must provide their Company Name, DUNS number, Physical Address, and Point of Contact Information. Interested organizations are required to identify their type of business, applicable North American Industry Classification System Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. All capability statements sent in response to this Sources Sought Notice must be submitted electronically (via email) to Farrin Stanton, Contract Specialist, at Farrin.Stanton@nih.gov in MS Word format by or before the closing date of this announcement. All responses must be received by the specified due date and time in order to be considered. The response must be received on or before July 11, 2014 12pm Eastern Standard Time. CONCLUDING STATEMENTS Note: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After review of the responses received, pre-solicitation and solicitation notices may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. The solicitation release date is pending. The Government intends to negotiate a fixed-price purchase order. Confidentiality. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA(SSSA)-SBSS-14-356/listing.html)
- Place of Performance
- Address: NIDA, 251 Bayview Bld, BRC Room 04A314, baltimore, Maryland, 21224, United States
- Zip Code: 21224
- Zip Code: 21224
- Record
- SN03408109-W 20140628/140626235614-669e09855e79a05fb4ba0fa614878cbc (fbodaily.com)
- Source
-
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