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FBO DAILY - FEDBIZOPPS ISSUE OF JUNE 15, 2014 FBO #4586
SOURCES SOUGHT

66 -- Olympus FV1200 ‘Basic’ Laser Scanning Confocal and Multi Photon Inverted Microscope Imaging System.

Notice Date

6/13/2014
 

Notice Type

Sources Sought
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
 

ZIP Code

20892-7902
 

Solicitation Number

HHS-NIH-NHLBI-CSB-(DE)-SBSS-2014-152-RSF
 

Archive Date

7/12/2014
 

Point of Contact

Rashida S. Ferebee, Phone: 3014352605
 

E-Mail Address

ferebeers@nhlbi.nih.gov
(ferebeers@nhlbi.nih.gov)
 

Small Business Set-Aside

N/A
 

Description

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. A. Background The National Institute of Health (NIH) mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The mission of the National Institute of Dental and Craniofacial Research (NIDCR) is to improve oral, dental and craniofacial health through research, research training, and the dissemination of health information. The Molecular Physiology and Therapeutics Branch of NIDCR pursue a comprehensive bench-to-bedside program to understand the molecular basis of salivary gland function and dysfunction and to develop strategies for the diagnosis, prevention, and management of salivary gland diseases. Clinical and translational studies focus on mechanisms of, and therapies for, salivary gland dysfunction caused by head and neck irradiation and diseases such as Sjogren's syndrome. The Branch will develop novel clinical strategies to restore salivary secretion that will include viral based gene transfer, pharmacological and other molecular tools. Large part of the work involves use of imageing techniques, specially within the context of studying function in live tissues and cells. NIDCR has developed technical and molecular tools to progress in this area of work. This requires highly skilled personnel as well as state of the art equipment that will allow optimum speed and resolution for data acquisition. Multiphoton imaging techniques allow detailed studies under truly physiological conditions. Olympus America Inc. is utilized as the core instrument manufacturer used in NIDCR labs. Currently NIDCR has various Olympus instruments, including the FV1000 confocal microscope and require that users and laboratory personnel be able to utilize existing optics and software knowledge in applying the added functionality and capabilities of the new confocal and multi photon system. The components and accessories for NIDCR's existing IX81 microscopes and FV1000 confocal microscope are only compatible with the Olympus FV1200 confocal and multi photon system. B. Purpose and Objectives Procure a FV1200 Multiphoton with InSight Laser and GaAsP, (Specified Brand Name: Olympus America Inc.) NO REFURBISHED OR USED SYSTEMS ARE ACCEBTABLE. C. Project/Contractor Requirements: Contractor shall deliver and install the following: 1. Confocal and Multiphoton Core Items FV1200 FILTER CORE SET; IX83,M_AR/559/635NM FV1000 405/440LD SET FOR FILTER DETECTOR & M- AR/559/635NM FV1000 LASER COMBINER W/SINGLE OUTPUT PORT 1 FV10-TD;TRANSMITTED LIGHT DETECTOR INSIGHT DS-OL;INSIGHT LASER 1LINE 680- 1300NM,W/BASE PLATE F12MPE BASIC LASER DELIV.OPTICS W/MPE FILTER SET FV12MP-IXDAD;EXTERNAL DETECTOR UNIT ADAPTOR FOR IX83 FV10MP-IXD-GAP; 2CH PMT+2CH GA ASP NON-DESCAN DETECTOR F/IX81 FV10MP-SDM-M;GaAsP NON-DESCAN DETECTOR MIRROR UNIT FV10-MRG/RW;GFP/RFP EM CUBE FOR 2+2 CH NON- DESCAN GaAsP DET FV10-MRVGR/XR; 4CH NDD FILTER, BFP/GFP/DSRED,380-560NM/DSRED E5-1620 3.60GHZ 8GB RAM,2TB HD,WIN 7-64BIT LINE POWER STABILIZER FOR PSU AND PC 4 SERIAL DIRECT CABLE,DB9 FEMALE TO FEMALE, 15 FEET LONG 658554705; DELL ULTRASHARP 30"MONITOR, 2560X1600 F10MMASW; MAPPING AND MULTI POINT SOFTWARE FV10-MSASW; SCANNING STAGE CONTROL SOFTWARE FOR F10PCSWA3 2. IX83 Microscope for Multiphoton FV1200 IX83 MICROSCOPE SET,W/O STAGE PROSCAN ENCODED XY STAGE KIT FOR IX73/83; 1MM PITCH 39000-BX3;AT-DAPI,375/28X,415BS,460/50M IN BX3 CUBE 31001;FL-CUBE FITC/EGFP FLUO 3/DIO ACRADINE ORANGE (+RNA) 31002;FL-CUBE TRITC(RHODSMINE) /DIL/CY3 EX540,BS565,EM605 3. Objectives UPLFLN10X2; U PLAN FLUORITE 10X OBJECTIVE; NA 0.3, WD 10MM UPLSAPO30XS;UPLSAPO N 30X SI OIL OBJ,NA 1.05,WD 0.8MM, W/CC UPLSAPO40XS;UPLSAPO N 40X SI OIL OBJ, NA 1.25,WD 0.3MM,W/CC UPASAPO60XS;UPLSAPO 60X SI OIL OBJ, NA 1.30, WD 0.30MM,W/CC UPLSAPO100XS;UPLSAPO 100X SI OIL OBJ, NA 1.35, W/CC IMMOIL-SI-F30CC;SILICON IMMER.OIL 30CC, FOR SI OBJ 4. DIC Optics and Condenser U-M636I IX3-FDICT;ANALYZER CUBE FOR DIC W/IX3-RFACS 6-U270 IX3-LWUCDA;MOT CONDENSER PHASE/DIC U-IFCBL100; CONNECTION CABLE FOR IX3 MOT ACCESS 100CM IX2-DIC40(F);NOMARSKI PRISM FOR 40X OBJECTIVE,38MM,IX2-LWUCD IX2-DIC60(F);NOMARSKI PRISM FOR 60X OBJECTIVE,38MM,IX2-LWUCD IX2-DIC100(F);NOMARSKI PRISM FOR100X OBJECTIVE,38MMIX2-LWUC U-DICTS(F);TRANSMITTED DIC PRISM SLIDER,SHIFT TYPE 5. Environmental Control Chamber WSKM-F1 SYS FOR 5% CO2.W/OTH-W-200F MULTIWELL LID, NECO SW WSKM, PPZI3, PLAM HOLDER, 35MM DISHES WSKM, PPZI3, PLAM HOLDER;CHAMB SLD,CHAMB CVGLSS,1X3 SLD KS-WSKM-D35; 35MM COVER F/PERFUSION BLOCKS, MAGNETIC 6. Anti-Vibration Table R2-125150H-OLY;ANTIVIBRA TABLE 1250X1500MM,BASIC & M-EXCL Unique Capabilities: • Multiphoton system comes equipped with new InSight laser from Spectra Physics. InSight laser provides the highest peak power across the widest range of wavelengths. • The FV1200 comes with anti--oxidizing silver galvanometers for scanning. This system provides the greatest reflection of visible and IR lasers on the market. • Both the multiphoton and visible side of the system are equipped with cooled GaAsP module for high-sensitivity imaging. For multiphoton imaging, two GaAsP channels are included for low-light imaging and two standard PMTs for brighter samples and far-red fluorophores. • Using methods similar to Random Access Scanning, Olympus Multipoint Mapping Advanced Software (MMASW) provides high speed measurement capability up to 50,000 Hz data output for functional imaging. Visible Confocal Capabilities: • Multi-channel spectral detection unit provides simultaneous or sequential 5 channel imaging. • Two spectral detectors capable of 1nm-100nm resolution. • Two channel high-sensitivity GaAsP module for live-cell imaging. These GaAsP show the same increase in sensitivity as those described above. • Transmitted Detector and optics for capturing DIC images at every magnification. • Multi-laser combiner provides a single fiber source of light at 405nm, 440nm, 488nm, 515nm, 559nm, and 635nm. • Motorized IX83 microscope is the newest stand on the market. Designed for live cell imaging, the IX83 comes with ZDC Autofocus and 10nm resolution in X, Y, and Z through a Prior Encoded Motorized Stage. • A removable stage-top Tokai Hit environmental chamber is included for usage with 100% CO2. The CO2 levels can be adjusted for different cell types. Perfusion mounts and 35mm dish lids are included. • The system can be used for multi-dimensional and multi-area time-lapse imaging using the multi-area time-lapse software module to control the motorized XY stage. The system images cell changes over time, efficiently capturing large amounts of data during a single experiment. Microscopes with Z-drift compensation and a CO2 incubator enable long time-lapse experiments. C. Inspection and Acceptance Requirements: • Upon arrival of equipment to destination, the package must be undamaged. • In the installation of the equipment, all parts must be functional and running properly. D. Anticipated Period of Performance 3-4 Months Upon Receipt of Contract Award E. Capability Statement/Information Sought Interested parties are expected to review this notice to familiarize itself with the requirements of this project. Failure to do so will be at your firm's own risk. The following information shall be included in the capability statement: 1. A general overview of the respondents' opinions about the difficulty and /or feasibility of the potential requirement, and any information regarding innovative ideas or concepts. 2. Information in sufficient details of the respondents' (a) staff expertise, including their availability, experience, and formal and other training; (b) current in-house capability and capacity to perform the work; (c) prior completed projects of similar nature; (d) corporate experience and management capability; and (e) examples of prior completed Government contracts, references, and other related information. 3. The respondents' DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HUBZone, etc) pursuant to the North American Industry Classification System (NAICS) code: 334516 Analytical Laboratory Instrument Manufacturing, small business size standard is 500 Employees. 4. Any other information that may be helpful in developing or finalizing the requirements of the potential acquisition. 5. The capability statement shall not exceed 10 single-sided pages (including all attachments, resumes, charts, etc.) presented in single-space and using a 12-point font size minimum, in either Microsoft Word or Adobe Portable Document Format (PDF), with 8-1/2 by 11 inch paper size, and 1 inch top, bottom, left and right margins. 6. All proprietary information should be marked as such. Statements should also include an indication of current certified small business status; this indication should be clearly marked on the first page of your capability statement (preferably placed under the eligible small business concern's name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner. CLOSING STATEMENT: The capability statement should be submitted electronically (via email) to Rashida Ferebee, Contract Specialist, at ferebeers@nhlbi. nih.gov, on June 27,2014, 9:00 A.M., EASTERN TIME and must reference synopsis number HHS-NIH-NHLBI-CSB-(DE)-SBSS-2014-152-RSF. All responses must be received by the specified due date and time in order to be considered. This Sources Sought Notice (SS) is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Heart, Lung, and Blood Institute (NHLBI). The NHLBI does not intend to award a contract on the basis of responses nor otherwise pay for the preparation of any information submitted. As a result of this notice, the NHLBI may issue a Request for Quote (RFQ). THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NHLBI shall arise as a result of a response to this notice or the NHLBI's use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. "Disclaimer and Important Notes. This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)."
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/HHS-NIH-NHLBI-CSB-(DE)-SBSS-2014-152-RSF/listing.html)
 

Place of Performance

Address: NIH/NIDCR, Bethesda, Maryland, 20892, United States

Zip Code: 20892
 

Record

SN03394929-W 20140615/140613234731-5f2871fac9c0d9fe5e1e50ec4c713ef9 (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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