SOURCES SOUGHT
Q -- Ultrastructural Analysis of Skeletal Muscle Fibers
- Notice Date
- 5/7/2014
- Notice Type
- Sources Sought
- NAICS
- 611310
— Colleges, Universities, and Professional Schools
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211 - MSC 9559, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-2014-207
- Archive Date
- 5/31/2014
- Point of Contact
- Rodney E. Brooks, Phone: 3014020751
- E-Mail Address
-
rodney.brooks@nih.gov
(rodney.brooks@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support Simplified Acquisitions, 9000 Rockville Pike, Bldg. 31, Room 1B57 Bethesda, MD 20892, UNITED STATES Introduction: This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources, (2) whether they are small businesses; HUBZone small businesses, service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. Background Information: The Mitochondria are organelles characterized for their highly dynamic structure, which relies on a controlled balance between biogenesis, fusion, fission, and mitophagy, resulting in alterations of mitochondrial ultrastructure under different physiological or pathological conditions. Aging and diet have a strong influence on mitochondrial physiology. However, the influence of these processes on the mitochondrial ultrastructure still requires further investigation. Purpose and Objectives for the Procurement: The purpose of the requirement is for the Ultrastructural analysis of skeletal muscle fibers. Contractor Requirements: The contractor shall provide: • Processing of skeletal muscle samples for obtaining resin blocks for electron microscopy. • The Examination of sequential ultrathin sections and collections of micrographs at the electron microscope. • Quantitative evaluation of micrographs by image analysis techniques. • Expert scientific assessment of the ultrastructiural modification elicited in skeletal muscle by the particular experimental condition under examination. • All equipment to perform the whole processing of samples, ultramicrotomy, electron microscopy and ultrastructural analysis of skeletal muscle fibers from experimentation animals or volunteers unde4r the different experimental conditions. • Perform various morphometric analysis on data related to the project, because of the complexity of the study. The contractor will work with data from multiple age groups, different sexes starting ages, and compound concentrations. The period of performance is July 7, 2014 - July 6, 2015. Capability Statement: Businesses that believe they possess the capabilities necessary to undertake this work should submit complete documentation of their capabilities to the Contract Specialist. The capabilities statement must specifically address each project requirement separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of scientists, medical experts and technical personnel as it relates to the above outlined requirements, 3) a description of general and specific facilities and equipment available, including computer equipment and software, 4) an outline of pervious research projects that are similar to the project requirements in which the organization and proposed personnel have participated, and 5) any other information considered relevant to this program. The capability statement must not exceed 15 single sided or 7.5 double sided pages in length and using a 12-point font size minimum. Interested organizations are required to identify their size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. All capability statements sent in response to this Sources Sought Notice must be submitted electronically (via email) to Rodney Brooks, Contract Specialist at rodney.brooks@nih.gov in MS Word within 7 calendar days of the date of this announcement. All responses must be received by the specified due date and time in order to be considered. This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After reviewed of the responses received, pre-solicitation and solicitation notices may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. The solicitation release date is pending. The Government intends to negotiate a fixed-price contract.
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