SOURCES SOUGHT
66 -- MSM 400 Semi-Automatic Yeast Dissection Microscope System
- Notice Date
- 7/31/2013
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Bldg 1050, Frederick, Maryland, 21702, United States
- ZIP Code
- 21702
- Solicitation Number
- SS-NCI-130102-TK
- Archive Date
- 8/20/2013
- Point of Contact
- Tiffany D. Kittrell, Phone: 2402765434
- E-Mail Address
-
Tiffany.kittrell@nih.gov
(Tiffany.kittrell@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- SOURCES SOUGHT NOTICE: MSM 400 Semi-Automatic Yeast Dissection Microscope System manufactured by Singer Instruments to be used in conducting research for the National Cancer Institute (NCI), Center for Cancer Research (CCR). Notice Number: SS-NCI-130102-TK Issued By: National Cancer Institute (NCI), Office of Acquisitions (OA) http://www.nci.nih.gov Key Dates: Capability Statement Due Date: August 5, 2013 by 4:00PM EST This Small Business Sources Sought Notice (SBSS) is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Cancer Institute (NCI). The purpose of this Sources Sought Notice is to identify qualified small business concerns including 8(a), HUBZone or Service-Disabled Veteran-owned business concerns that are interested in and capable of performing the work described herein. The NCI does not intend to award a contract on the basis of responses received nor otherwise pay for the preparation of any information submitted. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This requirement is assigned North American Industry Classification System (NAICS) code 334516 with a size standard of 500 employees. As a result of this Sources Sought Notice, the NCI may issue a Request for Quotation (RFQ) through FedBizOpps. THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NCI shall arise as a result of a response to this Sources Sought Notice or the NCI’s use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. The Laboratory of Biochemistry and Molecular Biology (LBMB) plans to procure on a sole source basis the MSM 400 Semi-Automatic Yeast Dissection microscope system manufactured by Singer Instruments to be used in conducting research into the underlying mechanisms of chromosome biology, including heterochromatin formation, chromosome segregation, chromosome organization, and telomere maintenance. This will allow NCI to discover the causative effect of defects in these fundamental processes, in particular as they pertain to the initiation of cancer cell states. Laboratories within LBMB investigate many aspects of chromosome biology, including heterochromatin formation, chromosome segregation, regulation of genome stability, and maintenance of telomeres. The laboratories study how chromosomes are accurately segregated, how they are organized, how compacted domains are formed, how gene expression patterns are regulated, and how structure contributes to the maintenance of genome stability. Particularly relevant to this acquisition is our use of the fission yeast model system, Saccharomyces pombe. Fission yeast provides a powerful model system with which to explore questions related to heterochromatin and telomere biology. In addition to the powerful genetic analysis available with the yeast system, S. pombe contains the basic machinery required for heterochromatin and telemore establishment, which is conserved in higher eukaryotes. This dissection microscope system will be used by members of LBMB for dissecting fungal spores to perform genetic analyses and strain constructions. This technique, called tetrad dissection, allows the analysis of gene function by the creation of mutant strains, as well as the genetic manipulation of the S. pombe genome to create useful strains for a variety of experiments to probe heterochromatin and telomere biology. The MSM 400 Semi-Automatic Yeast Dissection microscope system possesses the following salient characteristics: · Computer controlled, motorized platform for semi-automatic yeast spore dissection; Dissections can be performed through the eyepieces or by viewing the computer monitor; external image monitor is vital for teaching lab personnel the dissection technique · Automatic memory storage of cell placement positions for rapid re-localization to any point on an array · Micro Zapper, an electronically controlled device used for easy separation of spores, is used to vibrate the dissecting needle · Ability to create programs for automation of repetitive tasks · Digital CMOS camera for image capture of cells; ability to store and export images How to Submit a Response: 1. Page Limitations: Interested qualified small business organizations should submit a tailored capability statement for this requirement not to exceed 10 single sided pages including all attachments, resumes, charts, etc. (single spaced, 12 point font minimum) that clearly details the ability to perform the requirements of the notice described above. All proprietary information should be marked as such. Responses should include a minimum of a two pages demonstrating experience over the past two years meeting the requirements of this notice. Statements should also include an indication of current certified small business status; this indication should be clearly marked on the first page of your capability statement (preferable placed under the eligible small business concern’s name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner. 2. Due Date: <img src="file:///C:\DOCUME~1\KITTRE~1.NIH\LOCALS~1\Temp\msohtmlclip1\01\clip_image002.gif" alt="" width="2" height="44" /> Capability statements are due no later than 4:00 a.m. EST on August 5, 2013 3. Delivery Point: All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the unique specifications described herein. Written responses can be emailed to Tiffany Kittrell, Contract Specialist at Tiffany.kittrell@nih.gov or mailed to the address located under Point of Contact. All questions must be in writing and can be faxed to (240) 276-5399 or emailed. A determination by the Government not to compete this requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the System for Award Management (SAM) www.SAM.gov and the Online Representations and Certifications Applications (ORCA), http://orca.bpn.gov. No collect calls will be accepted. Please reference number SS-NCI-13012-TK on all correspondence. Disclaimer and Important Notes : This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, an RFQ may be published on FedBizOpps. However, responses to this notice will not be considered adequate responses to a solicitation(s). Point of Contact: Inquiries concerning this notice may be directed to: Tiffany Kittrell 9609 Medical Center Dr, Room 1E141 Bethesda, MD 20892-9705 Tiffany.kittrell@nih.gov
- Web Link
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FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/FCRF/SS-NCI-130102-TK/listing.html)
- Record
- SN03133318-W 20130802/130801000136-f0864d8914b8e3646d24d0f1b8ba7f4b (fbodaily.com)
- Source
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(may not be valid after Archive Date)
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