SOLICITATION NOTICE
66 -- Brand Name DeltaVision OMX with Blaze SIM Module and Elite Imaging System
- Notice Date
- 6/17/2013
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- NCI-130078-HN
- Archive Date
- 7/3/2013
- Point of Contact
- Huy Nguyen, Phone: 2402765570, Seena Ninan, Phone: 240-276-5419
- E-Mail Address
-
anh-huy.nguyen@nih.gov, ninans@mail.nih.gov
(anh-huy.nguyen@nih.gov, ninans@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The National Cancer Institute (NCI), Laboratory of Biochemistry and Molecular Biology (LBMB) plans to procure on a sole source basis the brand name DeltaVision OMX with Blaze SIM Module and Elite Imaging System from GE Healthcare BioSciences Corporation, 800 Centennial Ave, Piscataway, NJ, 08855-1327 USA. This acquisition will be processed under FAR Part 12 - Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1(b)(2) and 13.501-(a)(1) using simplified acquisition procedures for commercial acquisitions. The North American Industry Classification System code is 334516 and the business size standard is 500 employees. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. It has been determined that there is no opportunity to acquire green products or services under this contract. Delivery Date: 90 days from date of award. Laboratories within LBMB investigate many aspects of chromosome biology, including heterochromatin formation, chromosome segregation, regulation of genome stability, and maintenance of telomeres. Particularly relevant to this acquisition is the focus on the cell biology of chromosome structure and telomere biology. Telomeres are specialized protein-DNA structures located at the ends of chromosomes. Proper telomere maintenance is critical for many fundamental cellular processes, such as chromosome segregation, stem cell proliferation, and prevention of translocations that can lead to cancer. In order to investigate telomere function as well as other aspects of chromosome biology, such as chromosome organization, compaction, and structure, a high speed, super-resolution microscope capable of multiple imaging applications is needed to meet the goals of the laboratory. The system will be used to investigate the underlying mechanisms of chromosome biology, including heterochromatin formation, chromosome segregation, chromosome organization, and telomere maintenance, and to discover the causative effect of defects in these fundamental processes, in particular as they pertain to the initiation of cancer cell states. The DeltaVision OMX with Blaze SIM Module and Elite Imaging System possesses the following salient characteristics: • Equipped with 4 laser excitation optic assemblies (405, 488, 568 and 642nm) and 4 sCMOS cameras capable of wide field imaging at 400 frames per second. • Provide the capability for rapid automated switching between illumination channels as well as the ability to image either simultaneously or sequentially. • Microscope stage must be equipped with precision control motors to allow for precise stage control and stability for 3D imaging. • Ability to image thousands of specifically designated points of interest in a single time-lapse experiment. • The system shall be housed in an enclosure that can act as a darkroom, provide HEPA air filtration and positive pressure to reduce dust contamination of optical elements. Environmental control of temperature and CO2 conditions is also required for live cell imaging. • The system shall include two workstations - one dedicated to image acquisition and the other for image reconstruction and analysis - with all necessary software included. • The system should be equipped with a hardware autofocus module. • For structured illumination imaging, the system shall be able to acquire a 1um stack in 1 second per channel to enable imaging of live samples in super-resolution. In structured illumination mode, the system shall be capable of automatically optimizing X/Y/Z resolution for each channel acquired and should achieve 100-160nm resolution in X/Y and 280-350nm resolution in Z. • For 3D high resolution image acquisition, the system shall be capable of imaging at 400 frames per second in up to 4 channels simultaneously. • The system shall be equipped with software for deconvolution of wide field images. • The system shall include a fully integrated high resolution widefield fluorescence imaging system optimized for live cell imaging. • Stage mapping to the system used for 3D structural illumination is required for full integration and use as a spotting scope. This feature shall include a motorized X/Y/Z stage capable of marking designated points of interest. • The system shall include a 7 channel solid state illumination module with excitation for DAPI, CFP, FITC/GFP, TRITC, mCherry, Cy5. • A workstation shall be provided for image acquisition control and with software for quantitative iterative deconvolution, visualization, and quantification tools. GE Healthcare Biosciences Corporation is the only known contractor that can provide a system with the aforementioned salient characteristics. This is not a solicitation for competitive quotations. However, if any interested party, especially small business, believes they can meet the above requirement, they may submit a statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. The capability statement must be received at the NCI Office of Acquisitions on or before 4:00 PM EST on July 2, 2013. All responses and questions must be in writing and can be faxed (240) 276-5401 or emailed to Huy Nguyen, Contract Specialist at anh-huy.nguyen@nih.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through sam.gov. No collect calls will be accepted. Please reference solicitation number NCI-130077-HN on all correspondences.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/NCI-130078-HN/listing.html)
- Record
- SN03091340-W 20130619/130617235124-e6cd2ab36ecd719914b1a01f171f5276 (fbodaily.com)
- Source
-
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