SOURCES SOUGHT
66 -- Automated Western Blot System
- Notice Date
- 3/21/2013
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, 3900 NCTR Road, HFT-320, Bldg 50 | Rm 421, Jefferson, Arkansas, 72079, United States
- ZIP Code
- 72079
- Solicitation Number
- FDA1116382
- Archive Date
- 4/11/2013
- Point of Contact
- Crystal G. McCoskey, Phone: 8705437267
- E-Mail Address
-
crystal.mccoskey@fda.hhs.gov
(crystal.mccoskey@fda.hhs.gov)
- Small Business Set-Aside
- N/A
- Description
- MARKET RESEARCH PURPOSES ONLY NOT A REQUEST FOR PROPOSAL OR SOLICITATION This is a sources sought to determine the availability and capability of small business manufacturers or small businesses capable of supplying a U.S. made product of a small business manufacturer or producer. The associated North American Industry Classification System (NAICS) Code is‐ 334516 ‐ Analytical Laboratory Instrument Manufacturing; Small Business Size Standard is 500 employees. Part I: General Information (Introduction/Background/Scope) The U.S. Food and Drug Administration, is conducting market research to support the National Center for Toxicological Research (NCTR), Division of Genetic and Molecular Toxicology's requirement for one (1) instrument that provides an automated size based separation and nanoimmunoassay platform for the detection and characterization of protein molecular weights in denatured protein lysates. The system shall perform all steps typically associated with traditional Western analysis and provides true quantitation of results upon completion of the experiment. This instrument will be used on projects involving nanomaterials, including the Collaborative Opportunities for Research Excellence in Science (CORES) nanosilver project. There is evidence that one of the mechanisms by which nanomaterials cause genetic damage is through oxidative stress. The system shall elicit the underlying mechanism of genotoxicity associated with DNA damage and signal pathway changes. This instrument shall allow for rapid automated analysis and will be very important in NCTR research to understand the genetic hazards from exposure to nanomaterials. The particular research being conducted is for the determination of whether engineered silver nanomaterials behave differently than bulk silver in their ability to induce genetic damage. The requirement also includes installation, training and post‐warranty maintenance for up to 4 option years. The components and/or equipment shall be a newly manufactured, not used or refurbished, or previously used for demonstration. The entire system shall be warranted for parts and labor for a minimum of 12 months from date of installation acceptance. Part II: Work Requirements A. Technical requirements: The Division of Genetic and Reproductive Toxicology has a need for a fully automated complete solution for protein detection and characterization which performs all the manual processes associated with traditional western blot. This system should be able to accomplish protein separation and immunoassay detection in a nanoscale volume with the capability to analyze up to 96 data points in a single experiment. System shall include software for assay design, instrument programming and quantitative analysis of results and analyze run data. The system shall be able to: • Size, quantify, and immunodetect proteins • Process 12 samples per cycle • Run up to 8 cycles • Process 96 data points • Conduct sizing range of protein detection between 15-150kDa B. Installation and Testing Requirements: The vendor shall provide all labor, travel, and tools to install the equipment at the address provided below, to include inside delivery. Equipment must be tested once installed to verify all aspects of the system are operating within parameters of the required specifications. The vendor shall demonstrate upon installation and testing that the item meets all performance specifications. All standard information on the equipment, including but not limited to User Manuals, Operation and Maintenance (O&M) Manuals, Material and Safety Data Sheets (MSDS), troubleshooting guides and any other applicable documentation, shall be provided upon installation of the system. C. Post Warranty Service Requirements: • To include four (4) 1 year option periods to begin upon expiration of initial warranty period. • Unlimited On-Site Corrective Maintenance/Repairs shall be inclusive of all labor, travel, parts, components, subassemblies, etc. • Service contract coverage shall include unlimited trouble-shooting capabilities based on complete knowledge of the entire system, immediate access to certified replacement parts, and immediate access to improvements and new procedures provided by the original equipment manufacturer by phone, email, live-chat Interface, etc. • The Project Officer shall have access to the manufacturer's call center for technical assistance. The call center must be staffed by senior engineers to provide a high level of expertise for troubleshooting the system. • Service shall be provided by service engineers who are trained and certified by the original manufacturer. Engineers shall have access to the manufacturer's latest technical developments, repair procedures, application updates, diagnostic software, and planned maintenance procedures. • The vendor shall also include coverage for unlimited software and firmware updates and maintenance. D. Records and Reports: The Contractor shall, commensurate with the completion of each service call (inclusive of warranty service), provide the end-user of the equipment with a copy of a field service report/ticket identifying the equipment name, manufacturer, model number, and serial number of the equipment being serviced/repaired and detailing the reason for the service call, a detailed description of the work performed, the test instruments or other equipment used to affect the repair or otherwise perform the service, the name(s) and contact information of the technician who performed the repair/service, and for information purposes, the on-site hours expended and parts/components replaced. In addition, the Contractor shall provide a written report to the FDA COR and Contract Specialist, summarizing all maintenance and repair activities (including warranty work) each time service and/or repair is performed. Part III: Supporting Information A. Place of Performance Shall be delivered to, installed, tested and maintained at: 3900 NCTR Rd. Bldg 15-122B Jefferson, AR 72079 Vendor shall coordinate delivery and installation with Project Officer, Ms. Stacey Dial, 870-543-7783. B. Period of Performance Delivery, installation and training expected within 30 days of award with up to 4 post-warranty annual preventative maintenance option periods. Part III: Instructions to Prospective Respondents Responses to this sources sought shall unequivocally demonstrate that respondent is regularly engaged in the manufacture and/or sale of same or substantially similar items. Though the target audience is small business manufacturers or small businesses capable of supplying a U.S. made product of a small business manufacturer or producer all interested parties may respond. At a minimum, responses shall include the following: • Business name and bio, DUNS number, business address, business website, business size status (i.e., SB, VOSB, SDVOSB, HUBZone SB, 8(a), SDB, WOSB, EDWOSB, LB), point of contact name, mailing address (if different from business address), phone number and email address; [Provide this same information again for the manufacturer/producer if responding to provide a product manufactured by another firm.] • Three (3) years of past performance information for the manufacture and/or sale of same or substantially similar items, which are or have been used with same or similar equipment for same or similar purposes, to include date of sale, description (should also include technical literature and specifications), dollar value, client name, client address, client point of contact name, client point of contact mailing address (if different from that provided for client), client point of contact phone number, client point of contact email address, and name of the manufacturer (to include DUNS number and size status) if not the respondent; • Descriptive literature, brochures, specifications, marketing material, etc. detailing the nature of the items the responding firm is regularly engaged in manufacturing and/or selling; • If applicable, identification of the firm's GSA Schedule contract(s) by Schedule number and SINs that are applicable to this requirement; • If a large business, identify the subcontracting opportunities that would exist for small business concerns; • Although this is not a request for quote, informational pricing is encouraged; • The Government encourages any comments and/or suggestions from any interested party, regarding the specifications. While the Government will not respond directly to your comments and/or suggestions; we will consider them as we finalize the specifications in preparation for the forthcoming solicitation. The Government is not responsible for locating or securing any information, not identified in the response. Interested Parties must respond with capability statements which are due in person, by postal mail or email to the point of contact listed below on or before March 27, 2013 by 1:00 PM (Central Time in Jefferson, Arkansas) at the Food and Drug Administration, OC/OA/OAGS, Attn: Crystal G. McCoskey, 3900 NCTR Road, Bldg 50/Room 426, HFT‐320, Jefferson, AR 72079‐9502 or email crystal.mccoskey@fda.hhs.gov. Reference #1116382 in all correspondence with the point of contact listed above. Notice of Intent Responses to this sources sought announcement will assist the Government in determining whether this requirement should be set aside for small business, made available to full and open competition or procured through other than full and open acquisition procedures. Disclaimer and Important Notes This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a combined synopsis/solicitation (No. 1116382) may be published via FedBizOpps. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
FBO.gov Permalink
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- Record
- SN03017567-W 20130323/130321234502-8c9a8efe16dd807f46d2ae09c155fcdf (fbodaily.com)
- Source
-
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