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FBO DAILY ISSUE OF DECEMBER 16, 2012 FBO #4040
DOCUMENT

66 -- Retinal Imaging System - Attachment

Notice Date

12/14/2012
 

Notice Type

Attachment
 

NAICS

333314 — Optical Instrument and Lens Manufacturing
 

Contracting Office

US Department of Veterans Affairs;Veterans Health Administration;Service Area Office (SAO) East;323 North Shore Drive, Suite 500;Pittsburgh PA 15212-5319
 

ZIP Code

15212-5319
 

Solicitation Number

VA24013R0029
 

Response Due

12/19/2012
 

Archive Date

1/3/2013
 

Point of Contact

Ms. Cheryl Homison
 

Small Business Set-Aside

N/A
 

Description

THIS IS A SOURCES SOUGHT ANNOUNCEMENT ONLY. It is neither a solicitation announcement nor a request for proposals or quotes and shall not obligate the Government to award a contract. The purpose of this Sources Sought Announcement is for market research to gain knowledge of potential qualified sources interested and capable of performing the work and obtain their size classification relative to the North American Classification System (NACIS) Code 333314 with a size standard of 500 employees. SAO East is seeking sources of Micron III Retinal Imaging Systems, or a brand name or equal system that is compatible with the salient characteristics listed below. Research requirements: 1. Micron III (1 each) Studies are conducted using mice and rats as analogues for human diseases. In particular for the eye these studies examine retinal function, retinal disease, treatments, toxicity, and genetics. Such studies have been severely hampered by a robust ability to image the retinas in these animals. Such imaging is challenging because of the tiny size of the mouse eye, 3 mm, and the general difficulty of injecting light into the eye. Further, critical studies are dependent on the use of fluoresciene angiography and fluorescent molecules injected into the animal. SALIENT CHARECTERISTICS: A camera is required that can: Enable longitudinal studies, that is, enable the study of a single specimen over time, and provide bright field, fluroscience and Evan's Blue angiography, and fluorescent studies of arbitrary fluoropores across the visible spectrum. Technical performance parameters include: Real time digital video recording uncompressed with 24 bit resolution Ability to convert stored videos to AVI files Ability to export still frames into BMP, PNG, TIFF and JPEG formats Real time display to enable focusing and alignment Ability to insert arbitrary filter pairs for fluorescent imaging Ability to image both the rat and the mouse The system must be easy to use and include a goniostage for alignment of the animal The physical size must be such that it can fit onto the laboratory bench without using more than 1.5 meters of linear space. A system is required for which additional imaging and research modalities can be added such as anterior segment imaging, OCT, ERG, and laser photocoagulation It is also required that this camera be validated by current use in at least fifty major university centers. 2. Optical Coherence Topographer (1 each) Studies are conducted using mice and rats as analogues for human diseases. In particular for the eye these studies examine retinal function, retinal disease, treatments, toxicity, and genetics. Such studies have been severely hampered by a robust ability to obtain measurements of the retinal layers by a technique called optical coherence tomography. Such imaging is widely used for clinical work with humans; however, adopting these devices to animal work poses many challenges. Some systems have been adopted but they are physically large, the required space includes large carts in addition to laboratory bench space, and they must bear the cost burden associated with clinically approved devices. In the end, they are not optimized for imaging of the tiny mouse eye. More critically, they do not simultaneously obtain bright field images of the retina to guide the OCT scan to lie precisely across small but very important retinal feature. SALIENT CHARECTERISTICS: Technical performance parameters include: The optics have been specifically designed for the rodent eye The resolution is 2 microns Scans can be acquired in 2D and 3D The scan is guided from the bright field image so that it can be precisely guided over small lesions Image averaging will be robust with the eye stabilized to avoid averaging of images with motion artifacts The system will be compact not requiring any additional laboratory bench space over what is already required for a rodent retinal imaging microscope The system must record real time scans and the bright field image with the guide beam for documentation of the location of the OCT scan 3. Slit lamp imager for rodent eyes (1 each) Studies are conducted using mice and rats as analogues for human diseases. These studies include the anterior segment and in particular the cornea and the eye lens. Traditionally, anterior segment imaging in clinical practice is imaged using a device called a slit lamp. This actually is a low power microscope and a lamp to illuminate the anterior segment with a thin slit of light. This can allow the clinician to see the layers in the eye by projection of this slit diagonally to the eye. The slit width and height are adjustable and the color can be changed for use of topical fluorescein. These devices are built primarily for visualization and for imaging and documentation various ad hoc add-on cameras are used. And, the human slit lamp has its own very large stand, an unacceptable device in a crowded research laboratory. SALIENT CHARECTERISTICS: The device must be sized and scaled for the rodent eye, be optimized for imaging not visualization, and provide a field of view and resolution suitable for the 3 mm mouse eye and 6 mm rat eye. Technical performance parameters include: Field of view of 4 mm and with 4 microns resolution A slit of variable width up to 4 mm and down to zero width A variable height from 4 mm down to 1 mm White light and cobalt blue for topical fluorescein Extensive mechanisms to adjust the physical location and angle of the eye to the beams Two back fill lights, a requirement for imaging systems The system must be mounted on the retinal imaging system and not require additional laboratory space. 4. A laser injector (1 each) SALIENT CHARECTERISTICS: Laser photo coagulation is extremely difficult and requires a great deal of skill. When this technique is applied to mice and rats, the skill level requirement is greatly increased. The perspective is that for example the retinal area of the mouse eye seen in a single view has the transverse width of the human optical disk. Even a skill ophthalmologist finds it difficult to produce reliable laser energy injections. What is needed is a system that is sufficiently, easy to use so that laboratory technicians can deliver reliable photo coagulations. To this end the system must: Technical performance parameters include: Provide a real time image of the area of the eye where the laser energy is to be applied. Provide a real time image of the guide beam so that the location and focus of the guide beam are observable. Provide the ability to precisely focus and locate the guide beam. And then provide means to inject the laser energy controlling the power and the pulse length. REQUESTED INFORMATION: STATEMENT OF CAPABILITY: Submit a brief description (five [5] pages or less) that shows your company can provide the required services. One additional page may be included explaining experience in performing these services to the VA, other government agencies, or for private facilities. Potential sources should identify business name, point of contact, business size and any applicable business socio-economic category (i.e. small business, SDVOSB, VOSB, SB, etc), DUNS number, address, and any additional information felt to be pertinent. All vendors must be registered in CCR at the time of award. Responses to this notice should be electronically mailed in PDF format or word format to Cheryl.Homison@va.gov. Telephone responses will not be accepted. Written responses must be received no later than 3:00 PM (EST), Wednesday, December 19, 2012. Contracting Office Address: Department of Veterans Affairs; Service Area Office East, 323 North Shore Drive, Pittsburgh PA 15212. Place of Delivery: Uthsca Research Imaging Institute, Room 244 San Antonio, TX Type of Contract: Stand alone, Firm Fixed Price Contract. Point of Contact(s): Cheryl Homison Contracting Officer 412-822-3493 Cheryl.Homison@va.gov
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/notices/96fd2f89a2267be697ad4302c343c1ac)
 

Document(s)

Attachment
 

File Name: VA240-13-R-0029 VA240-13-R-0029.docx (https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=554158&FileName=VA240-13-R-0029-000.docx)

Link: https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=554158&FileName=VA240-13-R-0029-000.docx

 

Note: If links are broken, refer to Point of Contact above or contact the FBO Help Desk at 877-472-3779.
 

Record

SN02949494-W 20121216/121214234531-96fd2f89a2267be697ad4302c343c1ac (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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