SOLICITATION NOTICE
65 -- Plant Based Proteins
- Notice Date
- 9/18/2012
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 325411
— Medicinal and Botanical Manufacturing
- Contracting Office
- Other Defense Agencies, Defense Advanced Research Projects Agency, Contracts Management Office, 675 North Randolph Street, Arlington, Virginia, 22203-2114, United States
- ZIP Code
- 22203-2114
- Solicitation Number
- HR0011-12-R-0006
- Archive Date
- 11/6/2012
- Point of Contact
- Susan Shean,
- E-Mail Address
-
susan.shean@darpa.mil
(susan.shean@darpa.mil)
- Small Business Set-Aside
- N/A
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with the format under FAR Subpart 12.6 - "Streamlined Procedures for Evaluation and Solicitation for Commercial Items", as supplemented with additional information included in this notice. The Government intends to award multiple Indefinite Delivery - Indefinite Quantity (ID/IQ) contracts resulting from the combined synopsis/solicitation to the responsible offerors whose proposals, conforming to the combined synopsis/solicitation, are determined to be technically acceptable to the Government. Delivery orders will be competed among ID/IQ holders under separate solicitations issued at the time of the requirements. This announcement constitutes the only solicitation. Technical proposals are being requested and a written solicitation will not be issued. Solicitation number HR0011-12-R-0006 is issued as a Request for Proposal (RFP). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-59 and Defense Federal Acquisition Regulations Supplement Change Notice 20120615. This procurement is not set aside for small business. The NAICS Code for this solicitation is 325411. The classification code for this solicitation is 6505 Drugs, Biologicals and Official Reagents. The Small Business Size Standard is 750 employees. This is a multiple award, five-year Indefinite Delivery-Indefinite Quantity procurement on a Firm-Fixed-Price (FFP) and Time-and-Materials (T&M) basis. All responsible sources may submit a technical proposal which, if timely received, will be considered by the Agency. The Government intends to evaluate proposals and award multiple contracts without conducting discussions with offerors. Therefore, proposals submitted in response to the solicitation shall conform to all the requirements of this solicitation. However, at its discretion, the Government reserves the right to conduct discussions. The procurement is for the development and manufacture of plant based proteins from the Nicotiana benthamiana plant. Offerors may only provide a proposal for proteins from the Nicotiana benthamiana plant. The required items solicited are as follows: CLIN 0001: Plant Based Proteins -Specific proteins required will be identified in each delivery order -Indefinite Delivery - Indefinite Quantity -Firm-Fixed-Price -Lot CLIN 0002: Plant Based Proteins -Specific proteins required will be identified in each delivery order -Indefinite Delivery - Indefinite Quantity -Time & Materials -Lot In addition to the information required in accordance with FAR 52.212-1, offerors shall provide the following information: (1) Technical Approach The offeror shall explain its ability to rapidly express different types of recombinant plant (N. benthamiana) made proteins to include, but not limited to antigens for vaccines, enzymes, monoclonal antibodies, biologically active hormones and therapeutic proteins. The offeror shall explain its ability to grow, express proteins and process at least 300 kg of plant biomass per month in established validated production facilities. The offeror shall explain how it will ensure that the protein products delivered will be highly purified, characterized and meet specific lot release criteria, including the Certification of Analysis (CofA) for each protein. (2) Personnel and Facilities Capabilities Personnel: The offeror shall document the qualifications and availability of the proposed personnel identified by the offeror who are critical to successful accomplishment of the technical approach. For each proposed personnel, the extent of previous work experience and publications in the plant protein expression area and available time to devote to the project shall be clearly stated. The offeror shall provide resumes for each proposed personnel and clearly state any specialties that enhance the ability to complete the technical approach. The offeror shall outline the degree to which the offeror's proposed personnel represent any performance risk. Facilities Capabilities: The offeror shall identify the adequacy and extent to which its established facilities and equipment will support the achievement of the technical approach. The offeror shall identify its ability to rapidly express different types of recombinant plant (N. benthiamana) made proteins to include, but not limited to, antigens for vaccines, enzymes, monoclonal antibodies, biologically active hormones and therapeutic proteins. The offeror shall demonstrate its ability to grow, express, and process the final product proteins (including all downstream processes necessary for the requested purification) of at least 300kg of plant biomass per month in established and validated production facilities. The offeror shall explain its process to ensure that the protein products delivered are highly purified, characterized and meet specific lot release criteria, including the Certification of Analysis (CofA) for each protein. The offeror shall outline the degree to which the offeror's facilities represent any performance risk. (3) Past Performance and Experience The offeror shall provide past performance information pertaining to three (3) recent and relevant contracts for the same or similar work. The offeror shall include contract numbers, points of contact with telephone numbers and a description of the effort. The offeror shall provide Certificates of Analyses (CofA's) for its past performance references, if relevant. The offeror shall also provide details on: (a) how it adhered to contract schedules, including meeting interim milestones, and provided on-time completion of deliverables; (b) how it provided reliable performance and deliverables that conformed to contract requirements and standards of good workmanship; (c) how it was responsive to technical direction; (d) how it has relevant experience in protein processing of a specific product or different types of biological products (vaccines, enzymes, monoclonal antibodies, biologically active hormones and therapeutic proteins, etc) in the plant expression platform; and (e) how products were within the proposed budget. Proposal Format: All full proposals must be in the format provided below. Nonconforming proposals may be rejected without review. -All pages shall be printed on 8-1/2 by 11 inch paper with type not smaller than 12 point. -The proposal shall not exceed 25 pages. -The page limitation for full proposals includes all figures, tables, and charts. -The proposal may include an attached bibliography of relevant technical papers or research notes (published and unpublished), which document the technical ideas and approach upon which the proposal is based. Copies of not more than three (3) relevant papers can be included with the submission. The bibliography and attached papers are not included in the page count provided above. -The submission of other supporting materials along with the proposal is strongly discouraged and will not be considered for review. F.O.B. Destination (FAR 52.247-34) preferred. The Government will identify the date, time, and location of delivery in the individual delivery orders. Contractor's Federal Tax I.D., CAGE code, and DUNS number. The following FAR provisions are incorporated by reference and apply to this acquisition: 52.209-7 Information Regarding Responsibility Matters (Feb 2012) 52.212-1 Instructions to Offerors Commercial Items (Feb 2012) 52.212-2 Evaluation-Commercial Items (Jan 1999) The following evaluation factors will be assessed: Technical Approach (Factor 1) The offeror's ability to rapidly express different types of recombinant plant (N. benthamiana) made proteins to include but not limited to antigens for vaccines, enzymes, monoclonal antibodies, biologically active hormones and therapeutic proteins. The offeror's ability to grow, express proteins and process at least 300 kg of plant biomass per month in established validated production facilities. The offeror's explanation of how it will ensure that the protein products delivered will be highly purified, characterized and meet specific lot release criteria, including the Certification of Analysis (CofA) for each protein. Personnel and Facilities Capabilities (Factor 2) Personnel: The extent of the qualifications and availability of the proposed personnel identified by the offeror who are critical to successful accomplishment of the technical approach. For each proposed personnel, the extent of previous work experience and publications in the plant protein expression area and available time to devote to the project. The extent of the skill sets of the offeror's team needed to accomplish the technical approach. The degree to which the offeror's proposed personnel represent any performance risk. Facilities Capabilities: The extent and adequacy of the offeror's existing and established facilities and equipment to support achieving the technical approach. The ability of the offeror to rapidly express different types of recombinant plant (N. benthiamana) made proteins to include, but not limited to, antigens for vaccines, enzymes, monoclonal antibodies, biologically active hormones and therapeutic proteins. Offeror must be able to grow, express proteins and process at least 300 kg of plant biomass per month in established and validated production facilities. The extent to which the offeror identified its process to ensure that the protein products delivered are expected to be highly purified, characterized and meet specific lot release criteria, including the Certification of Analysis (CofA) for each protein. The degree to which the offeror's factilites represent any performance risk. Past Performance and Experience (Factor 3) The extent to which the offeror adhered to contract schedules, including meeting interim milestones and provided on-time completion of deliverables. The extent the offeror: provided reliable performance and deliverables that conformed to contract requirements and standards of good workmanship, and was responsive to technical direction; has relevant experience in protein processing of a specific product or different types of biological products (vaccines, enzymes, monoclonal antibodies, biologically active hormones and therapeutic proteins, etc.) in the plant expression platform; and provided Certificates of Analyses (CofAs) for these past performances, if relevant. The extent to which the offeror demonstrated products were within proposed budget. Basis for Award of the ID/IQ contracts: The Government intends to award multiple ID/IQ contracts to the offerors based on technically acceptable proposals with consideration given to the following factors: Technical Approach (Factor 1); Personnel and Facilities Capabilities (Factor 2); and Past Performance and Experience (Factor 3). Factors 1 and 2 are of equal importance and are both of greater importance than Factor 3. An unacceptable consensus rating in either Technical Approach or Personnel and Facilities Capabilities factors may render the entire proposal technically unacceptable. All offerors must include with proposal, if not registered in ORCA, a complete copy of the provision at FAR 52.212-3, Offeror Representations and Certifications-Commercial Items (Apr 2012) [Alt I]. The following FAR provisions are incorporated by reference and apply to this acquisition: 52.212-4 Contract Terms and Conditions-Commercial Items (Feb 2012) 52.212-4 Contract Terms and Conditions-Commercial Items (Oct 2008) [Alt I], 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items (May 2012), which under 52.212-5(b) incorporate by reference the following provisions: 52.203-6 Restrictions on Subcontractor Sales to the Government (Sept 2006)[Alt 1] 52.203-13 Contractor Code of Business Ethics and Conduct (Apr 2010) 52.204-10 Reporting Executive Compensation and First-Tier Subcontract Awards (Feb 2012) 52.209-6 Protecting the Government's Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment (Dec 2010) 52.209-9 Updates of Publicly Available Information Regarding Responsibility Matters (Feb 2012) 52.219-8 Utilization of Small Business Concerns (Jan 2011) 52.219-9 Small Business Subcontracting Plan (Jan 2011) 52.219-16 Liquidated Damages-Subcontracting Plan (Jan 1999) 52.219-28 Post Award Small Business Program Rerepresentation (Apr 2012) 52.222-3 Convict Labor (June 2003) 52.222-19 Child Labor-Cooperation with Authorities and Remedies (Mar 2012) 52.222-21 Prohibition of Segregated Facilities (Feb 1999) 52.222-26 Equal Opportunity (Mar 2007) 52.222-35 Equal Opportunity for Veterans (Sep 2010) 52.222-36 Affirmative Action for Workers with Disabilities (Oct 2010) 52.222-37 Employment Reports on Veterans (Sep 2010) 52.222-40 Notification of Employee Rights Under the National Labor Relations Act (Dec 2010) 52.222-54 Employment Eligibility Verification (Jan 2009) 52.223-18 Encouraging Contractor Policies to Ban Text Messaging While Driving (Aug 2011) 52.225-1 Buy American Act-Supplies (Feb 2009) 52.225-13 Restrictions on Certain Foreign Purchases (June 2008) 52.232-29 Terms for Financing of Purchases of Commercial Items (Feb 2002) 52.232-33 Payment by Electronic Funds Transfer-Central Contractor Registration (Oct 2003) 52.216-18 Ordering (Oct 1995) 52.216-19 Order Limitations (Oct 1995) 52.216-22 Indefinite Quantity (Oct 1995) 52.216-27 Single or Multiple Awards (Oct 1995) 52.216-31 Time-and-Materials/Labor-Hour Proposal Requirements-Commercial Item Acquisition (Feb 2007) 52.219-1 Small Business Program Representations (Apr 2012)[Alt 1] 52.223-3 Hazardous Material Identification and Material Safety Data (Jan 1997) 52.223-11 Ozone-Depleting Substances (May 2001) 52.227-11 Patent Rights-Ownership by the Contractor (Dec 2007) 52.232-99 Providing Accelerated Payment to Small Business Subcontractors (DEV)(Aug 2012) 52.233-3 Protest after Award (Aug 1996) 52.244-6 Subcontracts for Commercial Items (Dec 2010) The following DFARS provisions are incorporated by reference and apply to this acquisition: 252.203-7002 Requirement to Inform Employees of Whistleblowers Rights (JAN 2009) 252.204-7011 Alternate Line Item Structure (SEP 2011) 252.209-7001 Disclosure of Ownership or Control by the Government of a Terrorist Country (JAN 2009) 252.212-7000 Offeror Representations and Certifications-Commercial Items (JUN 2005) 252.212-7001 Contract Terms and Conditions Required to Implement Statutes or Executive Orders Applicable to Defense Acquisitions of Commercial Items (JUN 2012), which under 252.212-7001(a) incorporates by reference the following provisions: 52.203-3 Gratuities (Apr 1984) and which under 252.212-7001(b) incorporates by reference the following provisions: 252.203-7000 Requirements Relating to Compensation of Former DoD Officials (SEP 2011) 252.203-7003 Agency Office of the Inspector General (APR 2012) 252.205-7000 Provision of Information to Cooperative Agreement Holders (DEC 1991) 252.219-7003 Small Business Subcontracting Plan (DoD Contracts) (JUN 2012) 252.225-7012 Preference for Certain Domestic Commodities (JUN 2010) 252.225-7021 Trade Agreements (JUN 2012) 252.225-7036 Buy American-Free Trade Agreements-Balance of Payments Program (JUN 2012) 252.226-7001 Utilization of Indian Organizations, Indian-Owned Economic Enterprises, and Native Hawaiian Small Business Concerns (SEP 2004) 252.227-7013 Rights in Technical Data-Noncommercial Items (FEB 2012) 252.227-7015 Technical Data-Commercial Items (DEC 2011) 252.227-7037 Validation of Restrictive Markings on Technical Data (JUN 2012) 252.232-7003 Electronic Submission of Payment Requests and Receiving Reports (MAR 2008) 252.237-7010 Prohibition on Interrogation of Detainees by Contractor Personnel (NOV 2010) 252.243-7002 Requests for Equitable Adjustment (MAR 1998) 252.247-7023 Transportation of Supplies by Sea (MAY 2002) 252.225-7000 Buy American Statute-Balance of Payments Program Statute (JUN 2012) 252.225-7002 Qualifying Country Sources as Subcontractors (APR 2003), and 252.232-7010 Levies on Contract Payment (DEC 2006) The full text of clauses and provisions incorporated by reference may be obtained at the following addresses in accordance with FAR 52.252-2: http://www.acq.osd.mil/dp/dars/dfars.html http://farsite.hill.af.mil. Contractor(s) shall complete the Certifications and Representations via ORCA at the following address in accordance with FAR 52.212-3: http://orca.bpn.gov. Electronic Technical Proposals and the submitted Representations and Certifications are due to Susan Shean at Susan.Shean@DARPA.mil no later than 4:00 pm Eastern Time on 22 October 2012. The Government Point of Contact (POC) for submitting proposals or for other information regarding this solicitation is Susan Shean at Email Susan.Shean@DARPA.mil
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