SOLICITATION NOTICE
66 -- Fluorescence Imaging System
- Notice Date
- 9/18/2012
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- 2732321
- Archive Date
- 10/6/2012
- Point of Contact
- Hunter A. Tjugum, Phone: 3014358780
- E-Mail Address
-
hunter.tjugum@nih.gov
(hunter.tjugum@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a notice of intent, not a request for a proposal. A solicitation document will not be issued and proposals will not be requested. This is a notice of intent, not a request for a quotation. A solicitation document will not be issued and quotations will not be requested. National Institute on Drug Abuse, Office of Acquisitions- Neurosciences, Station Support/Simplified Acquisitions on behalf of the National Institute on Aging (NIA) intends to negotiate on a sole source basis with Ion Optix LLC, located at 309 Hillside Street, Milton, MA, 02186 for the purchase of an Ion Optix fluorescence imaging system. The vendor is to provide a fluorescent ion imaging system with integrated length and sarcomere measuring capability, including installation and training. The system is to include measurement capabilities for both dual-emission and dual excitation fluorescent dyes, field stimulation and thermostatic temperature control of sample. Simultaneous measurement of cell length by edge detection and sarcomere length is required. System is to be integrated on vendor supplied inverted microscope with vibration isolation. The software and hardware are proprietary, and are not available except from manufacturer. The proposed system replaces the in-house -designed and -built systems, in 1987, which are no longer serviceable due to attrition of key personnel. The Ion Optix system is similar to the in-house system as published in: Spurgeon, H.A., Stern, M.D., Baartz, G., Raffaeli, S., Hansford, R.G., Talo, A., Lakatta, E.G., and Capogrossi, M.C.; Simultaneous measurements of Ca2+, contraction and potential in cardiac myocytes; Am. J. Physiol. 258: H574-H586, (1990). Over 100 papers have been published by the lab using this in-house system. It is in the best interest of the Government to match as closely as possible the capability of the replacement system to this original system to provide optimal comparability of the data. This is a proprietary system for measurement primarily of calcium ions in live cell imaging. This is the only system designed to permit true simultaneous measurement calcium or other ions by fluorescence with measurement of cell contraction and sarcomere length thereby providing the ability to relate changes in ion concentration with cell response (contraction) at a millisecond time resolution. In addition, this system will use the dyes Indo-1 or Fluor-4 which have unique properties required by the lab's experimental tasks. Other systems use sampling methods which does not permit measurement of a single isolated cell and prohibits measurement of simultaneous electrophysiology parameters from the live cell. This acquisition is being conducted using policies unique to the acquisition of commercial items prescribed in FAR Part 12, in conjunction with the policies and procedures for solicitation, evaluation, and award prescribed in Part 13, Simplified Acquisition Procedures, and is exempt from the competition requirements of Part 6. This notice of intent is not a request for competitive proposals. Interested parties may identify their interest and capabilities in response to this synopsis. The determination by the Government not to compete the proposed contract based upon responses to this notice is solely within the discretion of the Government. Comments to this announcement, referencing this synopsis number, may be submitted to the NIDA SS/SA Branch, prior to the closing date specified in this announcement, electronically to the attention of Hunter A. Tjugum, at hunter.tjugum@nih.gov.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/2732321/listing.html)
- Record
- SN02887696-W 20120920/120919001415-c6aa19f851f083f6903353a414f0e2f1 (fbodaily.com)
- Source
-
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