SOLICITATION NOTICE
R -- A cross-sectional study of hematotoxicity in workers exposed to formaldehyde
- Notice Date
- 7/27/2012
- Notice Type
- Presolicitation
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd., EPS Suite 600, Rockville, Maryland, 20852
- ZIP Code
- 20852
- Solicitation Number
- NCI-120125-TG
- Archive Date
- 8/28/2012
- Point of Contact
- Terry Galloway, Phone: 301-402-4509, Caren N Rasmussen, Phone: (301) 402-4509
- E-Mail Address
-
gallowaytl@mail.nih.gov, cr214i@nih.gov
(gallowaytl@mail.nih.gov, cr214i@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd. EPS Room 6074, Rockville, MD, 20852, UNITED STATES Description The National Cancer Institute (NCI), Division of Cancer Epidemiology and Genetics (DCEG),Occupational and Environmental Epidemiology Branch (OEEB) plans to procure on a sole source basis A cross-sectional study of hematotoxicity in workers exposed to formaldehyde from Guangdong Poison Control Center, 68 Hai Kang Street, Xin Gang Road West, Guangzhou 510300. This acquisition will be processed in accordance with simplified acquisition procedures as stated in FAR Part 13.106-1(b)(1). The North American Industry Classification System code is 541990 and the business size standard is $7.0 million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. Period of Performance shall be from award through twelve (12) months. It has been determined there are no opportunities to acquire green products or services for this procurement. The Division of Cancer Epidemiology and Genetics (DCEG) is an intramural research program of the National Cancer Institute (NCI), National Institutes of Health (NIH) that conducts population and multidisciplinary research to discover the genetic and environmental determinants of cancer and new approaches to cancer prevention. Research in industrial workers and professionals exposed to formaldehyde suggests that occupational exposure to this important chemical is associated with increased risk for myeloid leukemia. However, there is still uncertainty about the biologic plausibility of the association because of questions regarding the ability of formaldehyde, which is extremely reactive, to directly or indirectly cause toxicity to the bone marrow. There have been several relatively small studies in China to evaluate the impact of occupational formaldehyde exposure on peripheral blood cells that have found some evidence that peripheral blood cells of the myeloid lineage (i.e., granulocytes, platelets) were significantly decreased in exposed workers. The NCI proposes to follow-up these preliminary findings in a larger study population in China (n = 600). This study will make an important contribution to the understanding of the leukemogenic potential of formaldehyde, which has important public health and regulatory implications. The contractor shall enroll 600 workers into a cross-sectional study of hematotoxicity in workers exposed to formaldehyde, review pre-employment physical examination and annual physical examination reports from all workers as far as possible to obtain the complete blood count (CBC). Using standard protocols which will be provided by the NCI at contract award, provide blood collection supplies and collect 17 ml blood sample from each subject. Using standard protocols provided by the NCI, collect buccal cell and urine samples from each subject and measure subjects for height, weight, and body temperature. The contractor shall deliver data in MS Excel format and quality control reports in MS Word format by email to NCI. Guangdong, China is an industrialized region with large workforces that are exposed to formaldehyde in factories that optimally suited for conducting a biomarker study and has ideal work place of characteristics for conducting this study. In order to confirm preliminary findings on formaldehyde hematotoxicity in China, the NCI must carry out a large cross-sectional study of formaldehyde exposed workers. Guangdong Poison Control Center is the only institute in Guangdong that has governmental access to conduct biomarker study of workers with occupational toxic exposures in Guangdong Province. There is no other contractor able to provide this service. This notice is not a request for competitive quotation. However, if any interested party believes it can meet the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Capability statements must be received in the contracting office by 11:00 AM EST, on August 13, 2012. For further information, please contact Terry Galloway, Contract Specialist via electronic mail at gallowaytl@mail.nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. No faxed or emailed capability statements will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA). Reference: NCI-120125-TG on all correspondence.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/NCI-120125-TG/listing.html)
- Record
- SN02818066-W 20120729/120727235903-a8c6ad196bdb042762ed3185badde546 (fbodaily.com)
- Source
-
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