SOLICITATION NOTICE
R -- Verbal and Orofacial Dyspraxia Study
- Notice Date
- 7/12/2012
- Notice Type
- Presolicitation
- NAICS
- 541690
— Other Scientific and Technical Consulting Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- 2580933
- Archive Date
- 8/3/2012
- Point of Contact
- Jasmine D Snoddy, Phone: 301 594 1571
- E-Mail Address
-
snoddyj@mail.nih.gov
(snoddyj@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a notice of intent, not a request for a proposal. A solicitation document will not be issued and proposals will not be requested. The National Institute of Drug Abuse (NIDA) Station Support/Simplified Acquisition (SS/SA) Branch, on behalf of the National Institute of Mental Health (NIMH) intends to negotiate and award a sole source purchase order to University College London (UCL), Gower Street, London WC1E 6BT, to study the differential roles of declarative and procedural memory in the acquisition of speech and language in patients with very early damage either to the hippocampal system in the medical temporal lobe or to the neostriatal system in the frontal lobe. The goal of the study is to apply multidisciplinary techniques to the study of patients with DA consequent to early pathology of the hippocampus, and of the affected members of the KE family with congenital pathology in the neostriatal/frontal system. Through the comparison of these two patient groups, NIMH aim to dissociate the contributions made by the two implicated brain systems to auditory memory generally, and, more specifically, to cognitive-based vs. habit-based memory for speech and language. The research will involve the application of neuropsychological, magnetic resonance, and electrophysiological techniques. In the course of a long-standing collaboration with a team of investigators at ICH, NIHM reported on two different neurodevelopmental disorders, one selectively affecting, long-term declarative or cognitive memory, and the other selectively interfering with articulate speech and language. NIMH termed the former Developmental amnesia and the latter Verbal and orofacial dyspraxia. Both of the neurodevelopmental disorders described about lead to disabling consequences: Early bilateral hippocampal pathology severely interfaces with episodic memory, thereby causing debilitating long-term effects on education and employment and precluding independence during adult life, while the genetically based, bilateral neostriatal/frontal abnormality seriously affects the ability to communicate intelligibly and to process speech and language. Therefore, besides the need to better understand both the phenotype and neural basis of these two developmental disorders, an additional goal is to explore the utility of different remediation techniques that might be applicable to new young cases as they are discovered during the course of the investigations. NIMH researchers has been in a long-standing collaboration with a team of investigators at the University of College London (UCL), Institute of Child Health (ICH), and Great Ormond Street Hospital for Children (GOSH), where access to appropriate patient populations is available. The team of investigators at ICH, along with Dr. Mishkin will report on two different neurodevelopmental disorders, one selectively interfering with articulate speech and language. The present team already have the expertise and experience to complete the proposed work thus it is cost efficient to continue the ongoing collaboration and certainly most effective scientifically to continue the work at ICH/GOSH. The period of performance is for One (1) Base Year and Three (3) One-Year Optional Years. Place of performance is at the UCL in London. The acquisition is being conducted under simplified acquisition using FAR 12 procedures and is exempt from the requirement of FAR Part 6, Competition Requirement. This notice of intent is not a request for competitive proposals. Interested parties may identify their interest and capabilities in response to this synopsis. The determination by the Government not to compete the proposed contract based upon responses to this notice is solely with the discretion of the Government. Comments to this announcement, referencing synopsis number 2580933 may be submitted to the NIDA, Station Support/Simplified Acquisition Branch, 31 Center Drive, Bldg. 31, Room 1B59, Bethesda, Maryland 20892-2080 and Attention: Jasmine Snoddy, Contract Specialist or email at Snoddyj@mail.nih.gov.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/2580933/listing.html)
- Place of Performance
- Address: Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN02801353-W 20120714/120712235741-4e778db7fd0ebb33672b0c682e7c716e (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |