SOLICITATION NOTICE
A -- DNA Methylation Services
- Notice Date
- 6/14/2012
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, Bldg 50 Room 422, Jefferson, Arkansas, 72079, United States
- ZIP Code
- 72079
- Solicitation Number
- 1105135
- Archive Date
- 7/12/2012
- Point of Contact
- Marcia O Park, Phone: (870) 543-7405
- E-Mail Address
-
marcia.park@fda.hhs.gov
(marcia.park@fda.hhs.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Part 13 and with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation, quotations are being requested and a written solicitation will not be issued. The solicitation number is 1105135, and is being issued as a Request for Quotation. The solicitation documentation and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-58, dated May 18, 2012. The associated North American Industry Classification System Code is 541711, Research and Development in Biotechnology, with a small business size standard of 500 employees. This acquisition is set aside for small businesses. Statement of Need Services are required to assess DNA methylation changes in four different cell types (2 lung, 1 endothelial and 1 heart) using microarrays. DNA methylation needs to be assessed by microarrays using Illumina Infinium chips. Samples will be analyzed so that comparison of the effect of tobacco smoke condensates on the methylation status of the cell's DNA can be made. DNA methylation changes will be used as biomarkers of exposure and harm to tobacco products. The Government requires pricing and ordering information for the following work: A total of 264 samples will be provided by the Government (half in August, 2012 and the other half in September, 2012). The Contractor shall: a. Provide extraction of cell samples and preparation of DNA followed by quantity and quality assessment b. Processing of the DNA and hybridization to Illumina Infinium chips to assess DNA methylation status according to the manufacturer's protocol/recommendations. c. Provide at least the following data summary reports in electronic format. 1. Display of chromosomal coordinated, 2. Percent GC Content 3. Location in a CpG Island 4. Methylation Beta values Period of performance for this service is one year after award of purchase order. An official authorized to bind the offeror must sign the terms and conditions of the offer. The provision at 52.212-1, Instructions to Offerors- Commercial Items, applies to this acquisition with the following addenda: The offeror agrees to hold the prices in its offer firm through September 30, 2012. The provision at 52.212-3, Offeror Representations and Certifications - Commercial Items, applies to this acquisition. The offeror shall complete only paragraph (b) of this provision if the offeror has completed the Annual Representations and Certifications electronically at http://orca. bpn.gov. The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition with the following addenda: This solicitation incorporates one or more FAR or HHSAR Clauses and provisions by reference, with the same force and effect as if they were given in full text. The full text may be accessed electronically at this/these address(es): http://www.acquisition.gov and http://dhhs.gov/asfr/ogapa/acquisition/acquisitionpolicies.html. 352.202-1 Definitions (Jan 2006) The Clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items, applies to this acquisition. The Contractor shall comply with the additional following Federal Acquisition Regulation (FAR) clauses, which are incorporated in this contract by reference, to implement provisions of law or Executive orders applicable to acquisitions of commercial items: a. 52.222-50 Combating Trafficking in Persons (FEB 2009) (22 U.S.C. 7104(g)). Alternate 1 (AUG 2007) of 52.222-50 (22 U.S.C. 7104(g)) 52.233-3, Protest After Award (AUG 1996) (31 U.S.C. 3553)52.233-4, Applicable Law for Breach of Contract Claim (Oct 2004) (Pub.L 108-77, 108-78). b. 52.204-10 Reporting Executive Compensation and First Tier Subcontracting Awards (FEB 2012) 52.219-4 Notice of Price Evaluation Preference for HUBZone Small Business Concerns (JAN 2011) (If the offeror elects to waive the preference, it shall so indicate in its offer) (15 U.S.C. 657a). 52.222-19 Child Labor - Cooperation with Authorities and Remedies (MAR 2012) (E.O. 13126) 52.222-21, Prohibition of Segregated Facilities (FEB 1999) 52.222-26, Equal Opportunity (MAR 2007) ((E.O. 11246) 52.222-36, Affirmative Action for Workers with Disabilities (OCT 2010) (29 U.S.C. 793) 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving (AUG 2011) (E.O. 13513) 52.225-3, Buy American Act - Free Trade Agreements _ Israeli Trade Act (MAR 2012) (41 U.S.C. 10a-10d, 19 U.S.C. 3301 note, 19 U.S.C. 2112 note, 19 U.S.C. 3805 note, Pub. L. 108-77, 108-78, 108-286, 108-302, 109-53, 109-169, 109-283, and 110-138. Alt I (MAR 2012) 52.225-5, Trade Agreements (Mar 2012)_ (19 U.S.C. 2501, et.seq., 19 U.S.C. 3301 note). 52.225-13, Restrictions on Certain Foreign Purchases (JUN 2008) (E.O.'s proclamations, and statutes administered by the Office of Foreign Assets Control of the Department of the Treasury). 52.232-33, Payment by Electronic Funds Transfer - Central Contractor Registration (OCT 2003) (31.U.S.C. 3332). This requirement is subject to the availability of Fiscal Year 2012 funds. Evaluation of offers: Award will be made to the lowest price, technically acceptable offeror. As a part of the offer, the offeror must furnish evidence that it has the ability to meet the above technical requirements. Offerors who fail to complete the required representations and certifications, or reject the terms and conditions of this solicitation may be excluded from consideration. All responsible sources may submit an offer, which if timely received, shall be considered. The offer must reference solicitation 1105145. The RFQ is due in person, by postal mail, fax or email to the point of contact by 1:00 PM Central Daylight Time, June 27, 2012. Any questions regarding this notice shall be submitted no later than 1:00 Pm CST, June 22, 2012 to the attention of Marcia Park at Marcia.park@fda.hhs.gov.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/FDA/NCTR/1105135/listing.html)
- Place of Performance
- Address: FDA/National Center for Toxicological Research, 3900 NCTR Road, Jefferson, Arkansas, 72079, United States
- Zip Code: 72079
- Zip Code: 72079
- Record
- SN02775899-W 20120616/120614235601-a5efb0e47ac026243fe62b4baacfa9c4 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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