SOLICITATION NOTICE
A -- Coronary Artery Risk Development in Young Adults (CARDIA) Study – Coordinating Center
- Notice Date
- 6/7/2012
- Notice Type
- Presolicitation
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- NHLBI-HV-13-16
- Point of Contact
- Elizabeth Zoller, Phone: 301-435-0374, Cheryl A Jennings, Phone: (301) 435-0347
- E-Mail Address
-
zollere@mail.nih.gov, cj19f@nih.gov
(zollere@mail.nih.gov, cj19f@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The National Heart, Lung, and Blood Institute (NHLBI) at the National Institutes of Health (NIH) plans to establish one (1) Coordinating Center as part of the Coronary Artery Risk Development in Young Adults (CARDIA) Study renewal. The CARDIA study involves a limited examination (Year 30) of the cohort in June 01, 2015 thru May 31, 2016; as well as continued follow-up contact and clinical events surveillance of the cohort. The Coordinating Center's effort is expected to begin on July 01, 2013 and to end on June 30, 2018. CARDIA began in 1985 in four U.S. communities (Birmingham, AL; Chicago, IL; Minneapolis, MN; and Oakland, CA). The original cohort (n=5,115) was selected to have approximately the same number of participants in subgroups of age (18-24 and 25-30), sex, race (black and white), and education (high school or less and more than high school) within each community. Seven additional examinations have been completed every 2-5 years, including a Year 25 examination completed in 2011. The objectives of the renewal of the CARDIA program are: (1) to perform a limited examination of the cohort to determine abnormalities in cardiac structure and function that exist in a community-based sample of mid-to-late middle-aged adults; to utilize novel measures to better understand myocardial dysfunction; to examine 25-year trajectories in cardiac structure and function; and to assess whether these abnormalities and trajectories differ between white and black adults; (2) to continue cohort follow-up for cardiovascular events, including heart failure, coronary heart disease, stroke, and atrial fibrillation; and (3) to provide a platform for ancillary studies particularly to the cohort examination, a training ground for new investigators, and support data sharing. These objectives will be accomplished through annual follow-up and a ninth (Year 30) examination of the existing cohort. The CARDIA Coordinating Center contractor shall be responsible for the tasks, including but not limited to the following: • Establish and manage laboratories, and other consultants and subcontracts, as necessary. • Coordinate development of the study protocol by the Steering Committee. • Oversee development of and coordinate Field Center staff training and certification and pilot testing. • Oversee central administrative aspects of participant recruitment/retention and participant satisfaction assurance. • Monitor implementation of the study protocol by the Field Centers, Reading Centers, and laboratories, in accordance with the study timelines. • Facilitate and coordinate the tracking of regular follow-up contact of participants. • Facilitate and coordinate the collection of data on clinical events and classification thereof. Provide a centralized abstractor to abstract event data from medical records, death certificates, and other relevant materials received from the Field Centers. • Perform administrative duties to support productive collaboration among the study centers and the NHLBI Project Office. • Maintain study databases. • Direct quality assurance and quality control programs. • Conduct statistical analyses for quality assurance, and scientific publications and presentations. • Create databases for investigators and the scientific community and support data sharing. • Contribute to new scientific developments within the study and work collaboratively with all centers to support early stage investigators in training. • Provide a plan for transition of responsibilities, data, and materials from the existing Coordinating Center to the new Offeror. • Formulate hypotheses/research questions, and propose and write manuscripts and ancillary studies to achieve the scientific goals of the study. This announcement is not a Request for Proposal (RFP), although one (1) award is anticipated, the Government is not committed to award a contract pursuant to this announcement. The RFP, NHLBI-HV-13-16, detailing the specifics of the project as well as information pertinent to the development of an offeror's proposal will be available electronically on or about June 21, 2012 and will be posted to Federal Business Opportunities website at: http://www.fedbizopps.gov under the NHLBI posting section. No paper copies will be available. Proposals will be due on or about October 9, 2012. It is anticipated that one (1) cost-reimbursement contract award with options will be made for a period of five years beginning on or about July 01, 2013. Offerors are responsible for downloading their own copy of the solicitation and amendments and for routinely checking the Internet site for any possible solicitation amendments that may be issued by the Government. The advertisement does not commit the Government to award a contract.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-HV-13-16/listing.html)
- Record
- SN02769814-W 20120609/120608000319-d682ef6855a27ac54bb02eafde4eb8ea (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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