SOURCES SOUGHT
A -- Chemical Synthesis Facility
- Notice Date
- 1/4/2012
- Notice Type
- Sources Sought
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Child Health and Human Development, Contracts Management Branch, 6100 Executive Blvd., Suite 7A07, MSC7510, Bethesda, Maryland, 20892-7510
- ZIP Code
- 20892-7510
- Solicitation Number
- NIH-NICHD-CPR-2012
- Archive Date
- 2/3/2012
- Point of Contact
- Timni Mahase, Phone: 301-435-8867, Adelola Kellum, Phone: 3014356955
- E-Mail Address
-
timni.mahase@nih.gov, kelluml@mail.nih.gov
(timni.mahase@nih.gov, kelluml@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Purpose of the Announcement: This is a Sources Sought notice. This is not a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of organizations for the proposed acquisition. Your responses to the information requested will assist the government in determining the appropriate acquisition method, including whether a set-aside is possible. Background: The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks capability statements from interested and qualified potential sources for a Chemical Synthesis Facility (CSF) capable of synthesizing potential anti-fertility agents on a laboratory gram scale to a relatively larger kilogram scale. The kilogram scale chemical agents are manufactured under current Good Manufacturing Practices (cGMP) for comprehensive contraceptive evaluation, including toxicology studies, primate testing and preclinical safety studies before entering human clinical studies. The requirements of this facility include the following: The Chemical Synthesis Facility (CSF) will be capable of • Rapidly synthesizing laboratory scale gram quantities of specific chemical compounds required for in vitro and initial contraceptive investigation in small animals, • Synthesize and purify relatively larger quantities of up to 10 kilograms of drug candidates for comprehensive anti-fertility testing by the Government, including toxicology studies, primate testing and preclinical and clinical studies under current Good Manufacturing Practices (cGMP), • Synthesizing chemicals and/or chemical intermediates of up to 10 kg for use in other ongoing chemical, peptide and related contracts and other contract programs, • Stable isotope and radiolabeled synthesis of compounds for pharmacokinetic and metabolism studies and • Peptide synthesis on a laboratory milligram scale to a larger scale of up to 1 kg that may require manufacture under cGMP. The radiolabeled and/or peptide synthesis may be sub-contracted out at cost with Project Officer's prior approval. The successful contractor maybe required to collaborate with other investigators in the CRHB research program in order to make progress toward the development of safe and effective male and female contraceptive drugs. Responses: Capability statements in response to this announcement should be no longer than 15 pages inclusive of all material. Responses will be evaluated on the basis of experience, expertise, and capabilities in the following technical areas: The anticipated contract type will be a cost reimbursement a base year of one year with four option years. The RFP is anticipated to be posted on or about March 23, 2012 on FedBizOpps (FBO) website: http://www.fedbizopps.gov. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. CONFIDIENTIALITY: No proprietary, classified, confidential, or sensitive information should be included in your response. The government reserves the right to use any non-proprietary technical information in any resultant solicitation(s). Information in the anticipated RFP supersedes any information in this pre-solicitation announcement. This acquisition has been designated as full and open competition under the North American Industry Classification System (NAICS) 541712 in the North American Industry Classification System (NAICS) and the size standard for such requirements is 500 employees. Interested organizations including Small Businesses that believe they possess the capabilities necessary to undertake this project should submit electronic copies in addition to two (2) hard copies of their capability statement, addressing the areas above. Please limit responses to five (5) pages or less. Any proprietary information should be so marked. Written capability statements should be received by the Contracting Officer by no later than 2:00 PM Eastern Time on January 19, 2011. Capability statements must identify the business status of the organization (i.e. educational institution, non-profit, large business, small business, 8 (a), or other corporate or non-corporate entity). NO COLLECT CALLS WILL BE ACCEPTED. RESPONDENTS MAY SUBMIT THEIR CAPABILITY STATEMENTS VIA E-MAIL IN ADDITION TO THE 2 HARD COPIES. Information submitted should be pertinent and specific in the technical area under consideration, on each of the following qualifications (1) Experience: an outline of previous projects, specific work previously performed or being performed and any in-house research and development effort; (2) Personnel: Name, professional qualifications and specific experience of scientist, engineers and technical personnel who may be assigned as principal investigator and/or project officer: (3) Facilities: Availability and description of special facilities required to perform in the technical areas under consideration, and a statement regarding industrial security clearance. Any other specific and pertinent information as pertains to this particular area of procurement that would enhance our consideration and evaluation of the information submitted. Information in the anticipated RFP supersedes any information in this pre-solicitation announcement. This acquisition has been designated as full and open competition under the North American Industry Classification System (NAICS) 541712 in the North American Industry Classification System (NAICS) and the size standard for such requirements is 500 employees. Inquiries should be directed to: Ms. Timni Mahase, Contracts Specialist, DHHS/NIH, National Institute of Child Health and Human Development, 6100 Executive Boulevard, Suite 7A07, MSC 7510, Bethesda MD 20892-7510, Rockville, MD 20852 (for overnight/express/courier service), telephone: 301-402-8867, fax: 301-402-3676, email: mahaset@mail.nih.gov OR Ms. Adelola Kellum, Contracting Officer, DHHS/NIH, National Institute of Child Health and Human Development, 6100 Executive Boulevard, Suite 7A07, MSC 7510, Bethesda MD 20892-7510, Rockville, MD 20852 (for overnight/express/courier service), telephone: 301-435-6955, fax: 301-402-3676, email: lk202p@nih.gov.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NICHD/NIH-NICHD-CPR-2012/listing.html)
- Place of Performance
- Address: Not applicable., United States
- Record
- SN02648772-W 20120106/120104234554-00add9236770ce16c470d23287ba8140 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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