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FBO DAILY ISSUE OF AUGUST 19, 2011 FBO #3555
AWARD

A -- Medicinal Chemistry for Neurotherapeutics Program (MCNP)

Notice Date
8/17/2011
 
Notice Type
Award Notice
 
NAICS
541711 — Research and Development in Biotechnology
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Institute of Neurological Disorders and Stroke, 6001 Executive Boulevard, Neuroscience Center, Suite 3287, MSC 9531, Bethesda, Maryland, 20892-9531
 
ZIP Code
20892-9531
 
Solicitation Number
NINDS-10-01
 
Archive Date
9/1/2011
 
Point of Contact
Annette Carter, Phone: (301) 496-5916, Kirkland L. Davis, Phone: (301) 496-1813
 
E-Mail Address
cartera@nida.nih.gov, kd17c@nih.gov
(cartera@nida.nih.gov, kd17c@nih.gov)
 
Small Business Set-Aside
N/A
 
Award Number
HHSN271201100013C
 
Award Date
8/17/2011
 
Awardee
Albany Molecular Research, Inc., 26 Corporate Circle, Albany, New York 12212, United States
 
Award Amount
$42,957,458 - Total value plus all possible options. See description for more detail.
 
Description
The National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), DHHS, through the NIH Blueprint Program Initiative and more specifically through the Medicinal Chemistry for Neurotherapeutics Program (MCNP) has awarded a 5-year contract to Albany Molecular Research, Inc., Albany, New York for the period August 17, 2011 through August 16, 2016. This contract shall provide medicinal chemistry services as part of an overall program effort to develop preclinical drug candidates - optimal drug leads that are ready for Investigational New Drug (IND) - enabling pharmacology and toxicology studies. The base contract award amount of $9,951,608 will cover acquisition of medicinal chemistry services associated with an initial project cohort called "Blueprint Cohort #1." In addition to the base contract, the Government shall also have the right to exercise a variety of additional individual medicinal chemistry study options during the five-year period of this contract. Future possible contract options are as follows: -- One (1) additional Blueprint Cohort, i.e. Blueprint Cohort #2, at a total estimated value of $9,644,514; -- Up to thirty (30) individual exploratory chemistry studies during the contract period, at a total estimated value of $4,543,772 if all 30 options exercised; -- Up to nine (9) Hit-to-Lead chemistry studies during the contract period, at a total estimated value of $10,595,341 if all nine options exercised; and -- Up to six (6) Lead-Optimization studies during the contract period, at a total estimated value of $8,222,223 if all six options exercised. Since the base contract and any subsequent option represents separate and distinct nonseverable requirements, each will be fully funded at the time each is awarded. Base contract and all possible options awarded on a cost reimbursement basis due to the nature and uncertainty of testing reiterations that might be necessary for an individual compound.
 
Web Link
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NINDS/Awards/HHSN271201100013C.html)
 
Record
SN02537784-W 20110819/110817235232-121fa14a9ed1e5065d0b13431d2c4f75 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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