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FBO DAILY ISSUE OF JANUARY 13, 2011 FBO #3337
SPECIAL NOTICE

A -- Sequence-Based Approach to Bioforensics Analysis (SBA) - BAA 11-04A Solicitation

Notice Date
1/11/2011
 
Notice Type
Special Notice
 
NAICS
541711 — Research and Development in Biotechnology
 
Contracting Office
Office of the Chief Procurement Officer, Washington, District of Columbia, 20528, United States
 
ZIP Code
20528
 
Solicitation Number
BAA11-04A
 
Point of Contact
Shelby Buford Jr., Phone: 202-254-5781
 
E-Mail Address
shelby.buford1@dhs.gov
(shelby.buford1@dhs.gov)
 
Small Business Set-Aside
N/A
 
Description
BAA 11-04A Solicitation The Department of Homeland Security (DHS) Science and Technology Directorate (S&T) Chemical and Biological Division (CBD) has a research opportunity to assist the Bioforensics Program in their search for technologies to achieve the following goals: • Development of an approach for generating a biased primer set that will preferentially amplify any of the NIAID Category A/B/C threat agents from within a complex background • Development of a production method for "ultraclean" reagents that are nucleic acid free for whole genome amplification (WGA). • Development of a comprehensive model of sequencing error that can be standardized across next-generation sequencing platforms and captures all types of sequencing error • Development of a probabilistic classifier for metagenomic sequence taxonomy assignment analysis that is applicable to both long and short fragments This announcement seeks whitepapers and proposals (in accordance with the attached Broad Agency Announcement (BAA) solicitation) with an emphasis on a particular aspect of the sequenced-based analytical approach in the following four technical focus areas (TFA's): TFA-1: Biased primer set design to amplify biological threat agents (BTAs) from complex backgrounds. TFA-2 Production methods for ultraclean reagents for WGA. TFA-3: Sequence data error model for next-generation and single molecule sequencing platforms. TFA-4 Taxonomic classification of metagenomic sequences.
 
Web Link
FBO.gov Permalink
(https://www.fbo.gov/spg/DHS/OCPO/DHS-OCPO/BAA11-04A/listing.html)
 
Place of Performance
Address: Washington, District of Columbia, 20528, United States
Zip Code: 20528
 
Record
SN02358296-W 20110113/110111234414-c406897b0d0002217beb1be16c4b47f8 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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