SOLICITATION NOTICE
A -- siRNA Studies for Nanotherapeutics - RFP S11-039 - siRNA Studies
- Notice Date
- 12/14/2010
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Bldg 1050, Frederick, Maryland, 21702, United States
- ZIP Code
- 21702
- Solicitation Number
- S11-039
- Archive Date
- 2/9/2011
- Point of Contact
- Matt DeSantis, , Shannon B Jackson,
- E-Mail Address
-
desantisma@mail.nih.gov, jacksonshannon@mail.nih.gov
(desantisma@mail.nih.gov, jacksonshannon@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Agreement Document RFP S11-039 siRNA Studies The purpose of this RFP is to identify and evaluate the clinical potential of candidate siRNA nanotherapeutics which have shown promise with respect to targeted delivery of siRNA to tumor cells, increased uptake of siRNA by tumor cells and/or increased circulation times of siRNA. Nanotechnologies which may minimize immune responses and/or off-target effects of siRNA are also of interest, but these characteristics are not required for the submission to be eligible. Researchers with promising in vitro data may submit proposals to conduct studies in small animal models of cancer; researchers with promising in vivo data in small animal models may submit proposals to conduct studies in large animal models. Appropriate small and large animal studies may include efficacy, toxicity, biodistribution, pharmacokinetics and/or pharmacodynamics. It is expected that data gathered under the resulting agreement will, in conjunction with other data generated by the offerors, enable filing of Investigational New Drug (IND) or Investigational Device Exemption (IDE) applications with the US-FDA. The purpose of this RFP is NOT to fund basic research on nanoplatform development, RNAi compounds and animal models. It is also not intended to fund ALL necessary studies needed to file an IND or IDE.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/FCRF/S11-039/listing.html)
- Place of Performance
- Address: Subcontractor's Location, United States
- Record
- SN02343643-W 20101216/101214234152-c405abb44ded6833956064e6ee3899b9 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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