SOURCES SOUGHT
A -- Respiratory Pathogens Research Centers (RPRC)
- Notice Date
- 10/21/2010
- Notice Type
- Sources Sought
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Office of Acquisitions, 6700 B Rockledge Room 3214 MSC7612, Bethesda, Maryland, 20892-7612
- ZIP Code
- 20892-7612
- Solicitation Number
- RFP-NIAID-DMID-NIHAI2010091
- Archive Date
- 11/16/2010
- Point of Contact
- Deborah A Baca, Phone: 301-443-4490, Michael Finn, Phone: 301-496-3699
- E-Mail Address
-
dbaca@mail.nih.gov, finnm@mail.nih.gov
(dbaca@mail.nih.gov, finnm@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- INTRODUCTION THIS SOURCES SOUGHT NOTICE IS TO DETERMINE THE AVAILABILITY OF POTENTIAL SMALL BUSINESSES (E.G., 8(A), SERVICE-DISABLED VETERAN OWNED SMALL BUSINESS, HUBZONE SMALL BUSINESS, SMALL DISADVANTAGED BUSINESS, VETERAN-OWNED SMALL BUSINESS, AND WOMEN-OWNED SMALL BUSINESS) THAT CAN PROVIDE THE REQUIRED LEVEL OF EFFORT, RESOURCES AND EXPERTISE TO CONTINUE TO PROVIDE THE DIVISION OF MICROBIOLOGY AND INFECTIOUS DISEASES (DMID), NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID), NATIONAL INSTITUTES OF HEALTH (NIH), DEPARTMENT OF HEALTH AND HUMAN SERVICES (DHHS) WITH THE CAPABILITY OF CONDUCTING TRANSLATIONAL AND CLINICAL RESEARCH FOCUSED ON THE DEVELOPMENT AND OPTIMIZATION OF CONTROL MEASURES FOR VIRAL AND BACTERIAL RESPIRATORY PATHOGENS. ALL SMALL BUSINESSES ARE ENCOURAGED TO RESPOND. THE NAICS CODE IS 541712 WITH A SIZE STANDARD OF 500 EMPLOYEES. The information from this market research will help the DMID, NIAID, NIH, plan their acquisition strategy. Please be sure to indicate if you have a GSA schedule contract, a contract on GSA 8(a) STARS, or a contract on GSA VETS GWAC. THIS IS STRICTLY MARKET RESEARCH. THE DMID, NIAID, NIH, WILL NOT ENTERTAIN QUESTIONS REGARDING THIS MARKET RESEARCH. BACKGROUND Under the current contracts, research progress has been made in several key areas. A major emphasis of the contract for vaccine respiratory pathogens research has been evaluating strategies to improve the effectiveness of influenza vaccines in populations at increased risk for complications from influenza and clinical studies of influenza vaccines with pandemic potential. The contract for bacterial respiratory pathogens research has focused on the development of a human challenge model for nontypeable Haemophilus influenzae, treatment strategies for pseudomonas infections, and diagnostic methods to discriminate between colonization and infection with S. pneumoniae. These contracts have also provided resources for the respiratory diseases research community, including reagents (e.g. strains, reagents, clinical specimens, data, etc.) and services (e.g., assay support and training). The purpose of this solicitation is to recompete this research program, under the title "Respiratory Pathogens Research Centers" (RPRC), to continue to provide DMID with the capability of conducting translational and clinical research focused on the development and optimization of control measures for viral and bacterial respiratory pathogens. Under the RPRC program, research on the emergence of drug-resistant pathogens such as S. pneumoniae, Haemophilus influenzae, as well as influenza and RSV and the impact of bacterial/viral co-infections on disease progression and severity will be emphasized. The RFP that will be issued will be composed of two parts with separate contracts to be awarded for each Part: PART A: Viral Respiratory Pathogens Research Center (VRPRC), and PART B: Bacterial Respiratory Pathogens Research Center (BRPRC). Together, these programs will comprise the NIAID Respiratory Pathogens Research Center (RPRC), which fills an important gap in NIAID's respiratory diseases research portfolio by supporting multidisciplinary translational and clinical research projects focused on developing information and tools and the evaluation of improved strategies for controlling these infections. Each new contract will be awarded as a term (level of effort), cost-reimbursement contract with a base period (one year) and six one-year options to extend the term for a total of seven years. Additional options to incrementally increase effort each year may be required to respond to emerging needs. In addition to the above, the contract will contain completion type options for the conduct of Phase 0/I, II, and III clinical and at least two innovation research projects each year for a period limited to two years each. It is estimated that one Phase I and one Phase II clinical trials may be awarded each year; it is estimated that two Phase III clinical trials will be awarded over the 7-year life of the contract. All options are subject to being exercised at the discretion of the Government and are subject to the availability of funds. RESPONSE INFORMATION In order to respond to this notice, contractors must be able to clearly convey its experience and/or ability to provide the following: 1. A total level of effort of 16,032 total direct labor per year based on a Work Year of 1,800 productive work hours (excluding vacation, holiday, sick leave) for a period of performance of seven years (Base period plus six, one-year Options). In any year of the contract, contractors must also be able to respond to requests to provide additional effort based on the exercise of Options in increments of 3,840, 5,760, or 9,600 direct labor hours (approximately 2 FTEs, 3 FTEs, and 5 FTEs, respectively) to increase the existing level-of-effort by up to a maximum of 36,480 direct labor hours (approximately 19 FTEs). Contractors must provide, for example, the following labor mix: a) Professional Support: Project Manager, Director of Collections, Director of Science; b) Technicians and Support: Technical Manager, Collection Scientist, Regulatory Specialist, Compliance Director, Marketing Manager, Field Acquisition Specialist, Technical Writers, Biologists; and c) Non-Professional Support: Operations Technician, Quality Systems Technician, Technical Service Representative, Customer Support staff, Clerical. 2. A Principal Investigator with the adequacy, appropriateness and relevance of expertise and experience with a project of similar size, scope, and complexity; qualifications. 3. Key professional and technical staff. 4. Organization and staffing to ensure efficient planning, initiation, implementation, conduct, and completion of all activities. 5. The ability to establish and maintain a multidisciplinary, collaborative, integrated, and iterative program focused on the conduct of research activities to understand the etiology and impact of viral and bacterial respiratory pathogens. 6. The ability to design, develop, conduct, and analyze translational studies. 7. The ability to design, develop, conduct, and analyze clinical research studies and trials, carrying out protocol development, implementation and management activities in compliance with NIAID Clinical Terms of Award (http://www.niaid.nih.gov/ncn/pdf/clinterm.pdf). 8. The ability to support short-term innovation research projects, designed to provide proof of principle data for highly innovative research projects. 9. The ability to ensure that contract-generated or acquired materials are made available to the research community and that clinical and translational data generated by the contract are released in publicly available databases. 10. The ability to organize and/or manage a Scientific Advisory Group. Each response should include the following Business Information: • DUNS. • Company Name. • Company Address. • Company Point of Contact, Phone and Email address • Current GSA Schedules appropriate to this Sources Sought. • Do you have a Government approved accounting system? If so, please identify the agency that approved the system. • Type of Company (i.e., small business, 8(a), woman owned, veteran owned, etc.) as validated via the Central Contractor Registration (CCR). All offerors must register on the CCR located at http://www.ccr.gov/index.asp Teaming Arrangements: All teaming arrangements should also include the above-cited information and certifications for each entity on the proposed team. Teaming arrangements are encouraged. Interested contractors must submit a capability statement for one or both Parts A and B; however, separate capability statements are required for each Part. The content of the capability statements shall be limited to five pages, excluding resumes, describing the company's experience and ability to perform this effort which includes the following: (1) a summary list of similar work previously performed or being performed; (2) the professional qualifications and specific experience of staff who may be assigned to the requirement; (3) the capability to provide the required level of effort on a continuing and emerging needs basis; (4) resumes for proposed key personnel, including the Project Director, which reflect education, and previous work relevant to the proposed requirement; (5) a general description of the facilities and other resources needed to perform the work; and (6) demonstrated ability to carry out the work. The maximum number of pages for submission is 20 pages. Responses must be submitted not later than November 1, 2010. Capability statements will not be returned and will not be accepted after the due date. E-mail and facsimile transmissions will be accepted. GENERAL INFORMATION This Sources Sought Notice is for information and planning purposes only and should not be construed as a commitment by the Government. This is not a solicitation announcement for proposals and no contract will be awarded from this Notice. No reimbursement will be made for any costs associated with providing information in response to this Notice. Respondents will not be notified of the results of this evaluation.
- Web Link
-
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- Record
- SN02314643-W 20101023/101021234012-6319eb55163a2f65293c574a9c31c4fb (fbodaily.com)
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