SOLICITATION NOTICE
68 -- Ub-CHOP2 Kit
- Notice Date
- 7/27/2010
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 325414
— Biological Product (except Diagnostic) Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- NHLBI-PB-(HG)-2010-253-JML
- Archive Date
- 8/17/2010
- Point of Contact
- Jonathan M. Lear, Phone: 3014514470
- E-Mail Address
-
learj@nhlbi.nih.gov
(learj@nhlbi.nih.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR A PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA), on behalf of the National Human Genome Research Institute (NHGRI), intends to negotiate and award a purchase order on a noncompetitive sole source basis to LifeSensors, Inc, 271 Great Valley Parkway, Malvern, PA 19355-1308 for a Ub-CHOP2 Kit with the following reagents: -USP2core, QTY - 2ml, Concentration - 50uM -CHOP2 Substrate, QTY - 75ml, Concentration - 4uM -Reagent Substrate, QTY - 10ml, Concentration - 25uM The sole source determination is based on the fact that LifeSensors is the only vendor who sells this assay principle as a kit. Ub-CHOP2 kits are fluorescent-based biochemical screening assays that are used to measure the deubiquination of CHOP2 by USP2a. USP2a has been identified as a possible drug target in prostate cancer and is hence of vital interest. This assay has performed very well in 1536-well format for validation and is now used to screen the DPI library. Concentration points have been lowered from six to four to cut costs. This kit was chosen because of its amenability to high-throughput screening and its easy-to-use reagents. Furthermore, compared to other components that can be purchased individually to optimize an assay to measure deubiquination by USP2a, this kit is economically feasible. The delivery point is the National Institutes of Health (NIH), National Human Genome Research Institute (NHGRI), Bethesda, MD 20892. Industry Classification (NAICS) Code is 325414, Biological Product (except Diagnostic) Manufacturing, and is a small business set aside. The acquisition is being conducted under FAR Part 13, Simplified Acquisition Procedures, therefore the requirements of FAR Part 6, Competitive Requirements, are not applicable and the resultant purchase order will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-44 (July 8, 2010). Interested parties may identify their interest and capabilities in response to this synopsis by August 2, 2010 at 3:00pm Eastern Standard Time. The determination by the Government not to compete the proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct future competitive procurement. Inquiries to this announcement, referencing synopsis number NHLBI-PB-(HG)-2010-253-JML, may be submitted to the National Heart, Lung and Blood Institute, Office of Acquisition, Procurement Branch, 6701 Rockledge Drive, Room 6151, Bethesda, Maryland 20892-7902, Attention: Jonathan Lear. Responses may be submitted electronically to learj@nhlbi.nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-PB-(HG)-2010-253-JML/listing.html)
- Place of Performance
- Address: National Institutes of Health/NHGRI, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN02218992-W 20100729/100727235307-3e1d8e0ab2d3ed249ef5f9684c94ff67 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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