SPECIAL NOTICE
B -- Performing HSV-2 Westernbolt Testing - RFQ
- Notice Date
- 4/14/2010
- Notice Type
- Special Notice
- NAICS
- 541690
— Other Scientific and Technical Consulting Services
- Contracting Office
- Department of Health and Human Services, Centers for Disease Control and Prevention, Procurement and Grants Office (Atlanta), 2920 Brandywine Road, Room 3000, Atlanta, Georgia, 30341-4146
- ZIP Code
- 30341-4146
- Solicitation Number
- 12008
- Archive Date
- 4/30/2010
- Point of Contact
- Deborah T Workman, Phone: 770-488-2889
- E-Mail Address
-
atl7@cdc.gov
(atl7@cdc.gov)
- Small Business Set-Aside
- N/A
- Description
- Use of Back-Scattering Inferometry Technology for the Development of Sexually Transmitted Infections Diagnostic Test NOTICE OF INTENT TO SOLE SOURCE: The Centers for Disease Control and Prevention (CDC) announces its intention to negotiate a sole source award with the Vanderbilt University Department of Chemistry, Nashville, TN to utilize Back-Scattering Interferometry (BSI) in developing new assays that will focus on detecting the presence of sexually transmitted disease (STD) antigens, including point-of-care test that potentially offer an alternative to traditional non-treponemal test (VDRL,RPR) and treponemal test (TP-PA, EIAs, FTA-Abs) and detect specific IgM antibody for the diagnosis of congenital syphilis. Currently, syphilis diagnosis is most commonly performed by serological tests, which are categorized into two groups: treponemal and non-treponemal tests. These tests have a variety of limitations, including that some of them can only be performed on serum and require quantities greater than 10 microliters. New technologies are being developed that can be adapted to sexually transmitted disease diagnosis, utilizing a reduced sample quantity as well as expanding the tests to whole blood, thereby mainstreaming the laboratory procedure by eliminating the requirement of venous blood collection. These technologies can be adapted to detect specific antigens and also organism-specific nucleic acid sequences by use of specific non-labeled probes. (BSI) is an advanced optical technique which allows for highly sensitive qualitative and quantitative, label-free detection of molecular interactions in free-solution or on-surface supports. BSI is a new technology which significantly accelerates assay development because it demonstrates zeptomole sensitivity, uses very small sample volumes (< 2 microliters), and requires little apriori knowledge of the molecular interactors.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/CDCP/PGOA/12008/listing.html)
- Place of Performance
- Address: 4333 Brooklyn Ave NE, Seattle, Washington, 98195, United States
- Zip Code: 98195
- Zip Code: 98195
- Record
- SN02121258-W 20100416/100414234621-dd69acd00c1000da87c977ea640051c2 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |