SPECIAL NOTICE
R -- Epidemiology Consultant
- Notice Date
- 2/19/2010
- Notice Type
- Special Notice
- NAICS
- 541690
— Other Scientific and Technical Consulting Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, Clinical Center/Office of Purchasing & Contracts, 6707 Democracy Blvd, Suite 106, MSC 5480, Bethesda, Maryland, 20892-5480
- ZIP Code
- 20892-5480
- Solicitation Number
- 171355
- Archive Date
- 3/16/2010
- Point of Contact
- Stacey M Polk, Phone: (301) 496-1446
- E-Mail Address
-
spolk@cc.nih.gov
(spolk@cc.nih.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- This is a Special Notice with the intent to Sole Source due to it's involvement with serveral active protocols, as well as research projects.. Background The Clinical Center (CC) is responsible for supporting the major programs of the NIH in on-campus clinical research. The CC encompasses elements of independent investigator-initiated research, research support, nursing, and support services. The Biostatistics and Clinical Epidemiology Service (BCES) within the Office of the Director (OD), CC, provides professional services and guidance involving clinical study design, data management, data analysis, and preparation of research reports and manuscripts, for numerous CC departments, committees, and selected NIH institutes. Deliverables The contractor will collaborate with researchers on numerous ongoing and new projects. Some of the ongoing projects include: •A complex study of manual muscle testing in the assessment of idiopathic inflammatory myopathies in children and adults. Requires collaboration with researchers from the CC Rehabilitation Medicine Department, NIEHS and NIAMS. (Protocol 94-E-0165 Studies on the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies) •A study of patients with idiopathic inflammatory myopathies and controls, using numerous ultrasound measures, MRI, dynamometry, MMT, physical assessments, exercise measures, and disease activity parameters. Requires collaboration with researchers from the CC Rehabilitation Medicine Department, NIEHS and NIAMS. (Protocol 94-E-0165 Studies on the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies) •A Nursing Department multicenter study of oral care in reducing oropharyngeal pathogens in critically ill patients. (Protocol 04-CC-0130 The Effect of a Systemic Oral Care Program on Reducing Exposure to Oropharyngeal Pathogens in Critically Ill Patients) •A natural history study of hepatitis C infection in a prospectively followed cohort of volunteer blood donors, involving researchers from the CC Department of Transfusion Medicine and NIAID. (Protocol 91-CC-0117 Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor Population) •A study of factors associated with symptoms of depression and anxiety in women with spontaneous 46,XX primary ovarian insufficiency, collaborating with researchers in NICHD. (Protocol 91-CH-0127 Ovarian Follicle Function in Patients with Premature Ovarian Failure) •A multi-institute study of women with spontaneous 46,XX primary ovarian insufficiency treated with testosterone, involving researchers from NICHD, NIMH, NEI, and Thomas Jefferson University. (Protocol 06-CH-0201 Effect of Transdermal Estradiol Replacement Therapy on Ovulation Rate in Women with Premature Ovarian Failure: A randomized, Placebo-Controlled Trial) •A study of timing of depression in women with spontaneous 46,XX primary ovarian insufficiency, collaborating with researchers in NIMH and NICHD. (Protocol 03-M-0175 The Effects of Acute Withdrawal of Estradiol on Mood Symptoms in Women with Perimenopausal Depression) • A multicenter and multi-institute study of patients with INCL, a rare disorder, involving researchers from the CC Department of Anesthesiology and Surgical Services, NICHD, NEI, NHGRI, Walter Reed Army Medical Center, and Children’s National Medical Center. (Protocol 01-CH-0086 A combination Therapy with Cystagon and N-Acetylcysteine for INCL Patients) The following studies involve analysis of animal studies: •A collaborative study of computed tomography scans to assess severity of bacterial pneumonia in a mouse model, involving researchers from the NIH Mouse Imaging Facility and CC Critical Care Medicine Department. (CC Animal Study Protocol #CCM 05-05 Computed Tomography Scans to Assess Severity of Bacterial Pneumonia in a Mouse Model—Pilot Study) •A collaborative study of anthrax protective antigen and monoclonal antibodies in dogs, involving researchers in the CC Critical Care Medicine Department. (CC Animal Study Protocol #CCM-09-06 The Effect of Conventional Hemodynamic Support or Protective Antigen Directed Monoclonal Antibody Alone or in Combination in a Large Animal Model of Anthrax) •A study with researchers from the CC Department of Anesthesiology and Surgical Services involving nociception and thermoregulation in mice with a genetic mutation to model Infantile Neuronal Ceroid Lipofuscinosis (INCL). (CC Animal Study Protocol #DASS 07-01 A Pilot Study of Nociception and Thermoregulation in a Murine Infantile Neuronal Ceroid Lipofuscinosis [INCL] Model) •A study with researchers from the CC Department of Anesthesiology and Surgical Services involving mice with polymicrobial sepsis. (CC Animal Study Protocol #DASS 07-02 The Effect of Nitric Oxide Synthase 1 and Vanilloid Receptor on Survival and Inflammatory responses in a Polymicrobial Sepsis Model) The following studies involve analysis of laboratory data without patient identifiers and do not have associated protocol numbers: •A study of discrepant blood cultures from lumens of indwelling catheters, involving researchers from NCI (Dr. Juan Geo-Banacloche), and DLM Microbiology Service (Dr. Patrick Murray). •A study of multi-laboratory reproducibility of MIC analyses of several Nocardia species among 7 national testing laboratories, in collaboration with DLM Microbiology Service (Dr. Frank Witebsky). Many projects are quite complex, often involving substantial databases developed over a number of years, requiring familiarity with hundreds of variables and archives of hundreds of analyses. It is anticipated that new projects will have similar characteristics. All these projects require (1) competency in performing varied statistical analyses using numerous statistical packages—such as StatView, JMP, SAS, nQuery, StatXact, and R; (2) meticulous attention to detail; and (3) substantial insight into and understanding of the clinical, medical, and biological aspects of the research areas. Period of Performance 3/15/10 through 9/30/10 Hours Up to 80 hours biweekly The anticipated award date is on or before 3/15/10 If there are any interested offerors please submit capabilities to provide services to spolk@cc.nih.gov. Otherwise the Government reserves the right to award to Deloris Koziol. Please submit any questions to spolk@cc.nih.gov
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/CCOPC/171355/listing.html)
- Place of Performance
- Address: NIH, 9000 Rockville Pike, Bldg 10CRC, Rm 72561, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN02070247-W 20100221/100219235817-4d920cff3bea64cd861eb2ddb5159887 (fbodaily.com)
- Source
-
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