SOURCES SOUGHT
A -- Novel Technologies in Newborn Screening
- Notice Date
- 1/19/2010
- Notice Type
- Sources Sought
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Child Health and Human Development, Contracts Management Branch, 6100 Executive Blvd., Suite 7A07, MSC7510, Bethesda, Maryland, 20892-7510
- ZIP Code
- 20892-7510
- Solicitation Number
- SS10-15
- Archive Date
- 2/13/2010
- Point of Contact
- Ross Kelley, Phone: 301-435-6960
- E-Mail Address
-
rk17a@nih.gov
(rk17a@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This announcement is not a Request for Proposals (RFP) and does not commit the Government to award a contract now or in the future. No solicitation is available at this time. The purpose of this synopsis is to identify small business organizations with requisite qualifications to provide the services stated herein. Based on capability statements received in response to this Sources Sought Announcement this acquisition may be solicited as a 100% small business set-aside. All small business organizations (SB, SDB, WOSB, HUBZone, VOSB, and SDVOSB) are encouraged to respond to this notice. This requirement is assigned a code of 541712 in the North American Industry Classification System (NAICS), and the size standard for such requirements is 500 employees. The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)/NIH, seeks capability statements from interested and qualified potential sources to develop multiplexed screening assays that can be automated and utilized in a high throughput environment for newborn screening. The end result may integrate a platform of screening technologies or even a single analytic technique that State Newborn Screening Programs or large commercial laboratories involved in newborn screening can adopt. The Screening technology platform of components may be based on a range of technologies that include, but are not limited to, microchip technologies, microbead technologies, nanotechnologies, microfluidics, DNA assays, biophysical assays, and/or technologies based on RNA or protein analysis. Offerors should propose a technology that tests for several conditions or an integrated platform of complementary technologies that can accomplish the screening of groups of conditions. These conditions might include inborn errors of metabolism, hematological disorders, congenital endocrinopathies, lysosomal storage diseases, chromosomal disorders (e.g., trisomies, monosomies), Fragile X syndrome, or those disorders characterized through control mechanisms of gene expression (e.g., epigenetics). NICHD prefers that the technology platforms integrate the testing of multiple groups of conditions and link to newborn screening informatic systems and encourages comparative effectiveness testing of different assays or technologies. NICHD is particularly interested in technologies that screen for "high priority" conditions with current or promising effective therapeutic interventions (e.g., Duchenne muscular dystrophy, spinal muscular atrophy, severe combined immunodeficiency, lysosomal storage diseases such as Pompe disease, Fabry disease, Krabbe disease, and the mucopolysaccharidoses), which presently lack sensitive and specific tests. A report, "Newborn Screening: Toward a Uniform Screening Panel and System" (httm://mchb.hrsa.gov/screening), which the Maternal and Child Health Bureau, Health Resources and Services Administration sponsored and the American College of Medical Genetics developed, identifies some of these "high priority" conditions. In this solicitation, a "high priority" condition is a condition for which the development of a screening test would make the condition amenable to newborn screening. Organizations that submit capability statements in response to this notice will be evaluated against the following technical areas of experience and expertise: 1.The ability to develop multiplexed screening assays that can be automated and utilized in a high throughput environment for newborn screening. 2.The ability to integrate a platform of screening technologies or even a single analytic technique which could be adopted by State Newborn Screening Programs or large commercial laboratories involved in newborn screening. 3.Experience in utilizing and developing a wide range of screening technologies including but not limited to the following: microchip technologies, microbead technologies, nanotechnologies, microfluidics, DNA assays, biophysical assays, and/or technologies based on RNA or protein analysis. 4.The ability to develop and utilize new technologies that screen for "high priority" conditions with current or promising effective therapeutic interventions or conditions that may in the future benefit from newborn screening. 5.The ability to develop bioinformatics for data collection and analysis. 6.The ability to conduct comparative effectiveness testing of different assays or technologies. Interested organizations that believe they possess the capabilities necessary to undertake this project should submit electronic copies in addition to four (4) hard copies of their capability statement, addressing the areas above. Please limit responses to fifteen (15) pages or less. Any proprietary information should be so marked. Written capability statements should be received by the Contracting Officer by no later than 4:30PM local time on January 29, 2010. Capability statements must identify the business status of the organization (i.e. educational institution, non-profit, large business, small business, 8 (a), or other corporate or non-corporate entity). NO COLLECT CALLS WILL BE ACCEPTED. RESPONDENTS MAY SUBMIT THEIR CAPABILITY STATEMENTS VIA E-MAIL IN ADDITION TO THE 4 HARD COPIES. Responses should be no more than 15 pages. These pages exclude resumes. INQUIRIES Lou Kuta Contracts Specialist National Institute of Child Health and Human Development 6100 Executive Boulevard, Suite 7A-07, MSC 7510 Bethesda MD 20892-7510 Rockville, MD 20852 (for express/courier service) Telephone: (301) 435-6965 Fax: (301) 402-3676 E-mail: lk240k@nih.gov OR Ross Kelley Contracting Officer National Institute of Child Health and Human Development 6100 Executive Boulevard, Suite 7A07, MSC 7510 Bethesda MD 20892-7510 Rockville, MD 20852 (for express/courier service) Telephone: 301-435-6960 Fax: 301-402-3676 E-mail: rk17a@nih.gov
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NICHD/SS10-15/listing.html)
- Record
- SN02044364-W 20100121/100119234640-d373b801cddad16929acd8ae07a5962e (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |