SOLICITATION NOTICE
66 -- MicroPoint Laser System Upgrade
- Notice Date
- 12/14/2009
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd., EPS Suite 600, Rockville, Maryland, 20852
- ZIP Code
- 20852
- Solicitation Number
- NCI-100030-MM
- Archive Date
- 1/14/2010
- Point of Contact
- Melissa P Marino, Phone: 301-402-4509, Caren N Rasmussen, Phone: (301) 402-4509
- E-Mail Address
-
marinome@mail.nih.gov, cr214i@nih.gov
(marinome@mail.nih.gov, cr214i@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Boulevard, EPS Suite 600, Room 6072, Rockville, MD 20852, UNITED STATES. Description The National Cancer Institute (NCI), Center for Cancer Research (CCR), Laboratory of Biochemistry and Molecular Biology (LBMB), plans to procure on a sole source basis with Photonic Instruments Inc., 2435 Dean St., Unit A, St. Charles, Illinois 60175 for an upgrade of a MicroPoint Laser System with computer controlled galvanometer beam-steering module. This acquisition will be processed in accordance with simplified acquisition procedures as stated in FAR Part 13.106-1(b)(1). Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. Delivery will be within 30-60 days of receipt of order. The LBMB investigates molecular and biochemical processes of chromosomes structure, remodeling and inheritance. In addition to numerous biochemical, molecular genetics and molecular biology techniques employed in these studies, researchers at LBMB also utilize live cell imaging to address in vivo distribution and dynamics of chromatin proteins and complexes tagged with GFP and other fluorescent tags. The LBMB's requires a high power laser beam with the ability to illuminate diffraction limited area of the live yeast cell nucleus. Other necessary characteristics include ability to choose illumination wavelength, precise control of laser power, proper safety interlocks to protect operator from injury. Due to fast rotation of yeast nucleus, such laser needs to be equipped with beam-steering optics allowing fast targeting of areas to be illuminated. Moreover, control software needs to interface with data generated by separate imaging camera and computer in such a way as not to interfere with their operations. The whole laser and steering optics need to be mounted on the rear aperture port of the inverted microscope - therefore they need to be compact and have proper adapters. The LBMB has an older model Micro-Point system (with stationary laser beam). This unit satisfies requirements regarding laser power, available laser emission wavelengths and ability to concentrate laser beam to a diffraction limited spot of about 250nm diameter at the focal point of microscope objective. However, to make it suitable to current experimental conditions, it needs to be upgraded by the addition of computer-controlled galvanometric beam displacer module. Because this is an upgrade of an existing older instrument, necessary parts and service are highly specialized and cannot be obtained from other sources without potentially compromising operation of the instrument as well as safety of personnel using it, as it contains high-power nitrogen laser-pumped dye laser. The technical characteristics of the required upgrade are listed below: •Addition of beam steering optics (galvanometer controlled mirrors) to existing MicroPoint Laser System (manual, stationary beam version) manufactured by Photonics Instruments Inc. •Addition of proper mechanical adapters to attach instrument to Zeiss AxioObserver Z1 inverted microscope •Software, frame grabber card and video converter to allow interfacing with existing camera (Hamamatsu C9100-13) and imaging computer Technical requirements for galvanometer controlled mirrors and auxiliary optics: •required to withstand peak laser pulse of at least 12kW at pulsewidth of 3-5nsec. •Required to maintain diffraction limited, circular spot (250nm diameter) at focal point of 100x microscope objective. •Reflectivity range of mirrors and transmission range of all other optical elements: 365nm to 700nm •No effects on polarization characteristics of the original laser beam. •Attenuation filter: Motorized, 90 steps, 0.1%-100% transmission Technical requirements for computer control interface: •USB •Control features: Beam pointing (x and y), attenuation, laser trigger (fire) command •Resolution: 8 bit equivalent with FOV range switching •Field of view range switching: 100%, 80%, 60%, 40%, 30% (selectable) Mechanical adapter requirements •Adapter for rear port of Zeiss AxioObserver microscope •Illumination port clear aperture: Ø22mm - Ø34mm •Illumination port filter size: Ø25mm - Ø38mm This is not a solicitation for competitive quotations. However, if any interested party believes they can meet the above requirement, they may submit a statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. An original and one copy of the capability statement must be received in the NCI contracting office on or before 11:00 AM EST on December 30, 2009. No electronic capability statements will be accepted (i.e. email or fax), an original and one copy must be sent to the NCI Office of Acquisitions at the address stated above. All questions must be in writing and can be faxed (301) 402-4513 or emailed to Melissa Marino, Contract Specialist at marinome@mail.nih.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the Central Contractor Registration (CCR) www.ccr.gov and the Online Representations and Certifications Applications (ORCA), http://orca.bpn.gov. No collect calls will be accepted. Please reference solicitation number NCI-100030-MM on all correspondence.
- Web Link
-
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(https://www.fbo.gov/spg/HHS/NIH/RCB/NCI-100030-MM/listing.html)
- Record
- SN02023153-W 20091216/091214234521-fcf0e7eeca9d0afc83053947c79c0006 (fbodaily.com)
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-
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