SOLICITATION NOTICE
A -- Serum Trace Element Concentrations & Risk of Esophageal Cancer
- Notice Date
- 8/18/2009
- Notice Type
- Presolicitation
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd., EPS Suite 600, Rockville, Maryland, 20852
- ZIP Code
- 20852
- Solicitation Number
- NCI-90178-MM
- Archive Date
- 9/17/2009
- Point of Contact
- Melissa P Marino, Phone: 301-402-4509, Caren N Rasmussen, Phone: (301) 402-4509
- E-Mail Address
-
marinome@mail.nih.gov, cr214i@nih.gov
(marinome@mail.nih.gov, cr214i@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The National Institutes of Health (NIH), National Cancer Institute (NCI), Division of Cancer Epidemiology and Genetics (DCEG), Nutritional Epidemiology Branch, intends to procure on a sole source basis services regarding serum trace element concentrations and risk of esophageal cancer with the University of Missouri-Columbia, Columbia, MO 65211-3400. This acquisition will be processed in accordance with simplified acquisition procedures as stated in FAR Part 13.106-(b)(1). The North American Industry Classification System Code is 541712 and the business size standard is 500. The period of performance will be twelve (12) months from date of award. Only one award will be made as a result of this solicitation. This is a firm fixed price type contract. Esophageal cancer is the fifth leading cause of cancer death worldwide, yet the etiology is poorly understood. The Nutritional Epidemiology Branch (NEB) conducts intramural research in the areas of nutrition and cancer, genetics and cancer, and cancer prevention. The Nutritional Epidemiology Branch, is currently examining the hypothesis that differences in element status are associated with the different risks of esophageal cancer. The NIT cohort has been followed for greater than 25 years and has accrued over 2000 incident esophageal cancer cases. Serum element concentrations will be measured in 1400 subjects to assess the association between serum trace elements and the risk of esophageal cancer. The current acquisition is based on the need to generate data on serum element concentrations using an efficient, sample-minimizing, and demonstrably valid method. The NIT Cohort Study provides one of the only analytical epidemiologic studies of esophageal squamous cell carcinoma that collected an appropriate biological sample and has very large numbers of cases. The University of Missouri Research Reactor has developed a multi-element serum measurement method that can provide accurate and reliable measurement of a broad spectrum of elements, including Cu, Fe, Zn, Mn, Co, Pb, Cd, & Mg in serum samples <300 μl. Using Inductively Coupled-Mass Spectrographic analysis, MURR can determine the concentrations of the full suite of elements from the existing small serum sample. Other methods, such as atomic absorption, can only measure single elements or require more sample volume. Also, the services provided by the Missouri Research Reactor have previously been demonstrated to provide accurate and valid measurements acceptable for publication in the peer reviewed literature. Furthermore, use of MURR will ensure that the measurements are comparable to those already completed by MURR using a different biological sample (i.e. toenails). Other service providers that can measure the full suite of required elements and that have already demonstrated valid measurements are unknown. This is not a solicitation for competitive quotations. However, if any interested party believes it can meet the above requirement, they may submit a statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. An original and one copy of the capability statement must be received in the NCI contracting office on or before 11:00 AM EST on September 2, 2009. All questions must be in writing and can be faxed to (301) 402-4513 or emailed to Melissa Marino, Contract Specialist at marinome@mail.nih.gov. It is the vendor's responsibility to call (301) 402-4509 to verify questions have been received. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration/certification in the Central Contractor Registration (CCR) www.ccr.gov and the Online Representations and Certifications Applications (ORCA), http://orca.bpn.gov. No collect calls will be accepted. Please reference solicitation number NCI-90178-MM on all correspondence.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/NCI-90178-MM/listing.html)
- Record
- SN01917000-W 20090820/090819001816-ccc342e7646eb3b3adbab35a85d12b6c (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |