SOLICITATION NOTICE
66 -- Fluorescence Microscope System
- Notice Date
- 8/12/2009
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 10401 Fernwood Drive, Suite 2NE70, MSC 4811, Bethesda, Maryland, 20817
- ZIP Code
- 20817
- Solicitation Number
- RFQ9081
- Archive Date
- 9/11/2009
- Point of Contact
- Reyes Rodriguez, Phone: 301-402-6074, Linda C Taylor, Phone: 301-402-5762
- E-Mail Address
-
rodriguezra@niaid.nih.gov, ltaylor@niaid.nih.gov
(rodriguezra@niaid.nih.gov, ltaylor@niaid.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a combined/synopsis solicitation Request for Quotation for commercial items prepared in accordance with the format in FAR subpart12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. The solicitation number for this acquisition is RFQ9081 and the solicitation is being issued as a Request for Quotation. This solicitation document and its incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC2005-35. This acquisition will be processed under simplified Acquisition Procedures (SAP) and is not a small business set-aside. Small and disadvantage businesses are encourage to submit a quotation on this requirement. The North American Industry Classification System (NAICS) code is 334516, which has a size standard of 500 employees. The National Institute of Allergy and Infectious Diseases (NIAID) intends to procure a fluorescence microscope system based on the following specifications: 1) Microscope that features 2, 3, 34 Channel - VIS and NLO (1P and 2P) system that Incorporates Primary Dichroioc Beam Splitter(Twin Gate) which achieves extremely High laser suppression, on the order of 6-7 OD, allowing superb reflection free imaging; Free selection of emission bands for detection possible to set the emission bands over laser lines due to effective laser blocking and freely rotatable scan field (0-360 degree in 0.1° steps). Multiple (up to 99) freely definable real regions of interest (rROIs). Pixel precise control of the laser intensity and signal detection. Prevention of photo damage outside the rROIs boundaries necessary for work on living cells, FRAP, uncaging, photoactivation and photoconversion experiments with individual AOTF settings (line selection and attenuation) per rROI. Capable to use up to 8 laser(s). 14 different scan speed levels (28 levels including bi-directional scans). Possible to select different scan speeds for bleach ROIs and image frame. Variable scan field size (hardware-zoom) from 0.6 to 40 in 0.1 steps for magnifications until the optical limits of resolution, with a scan field of 20 mm diagonally in the intermediate image plane. Image format from 4x1 to 6144x6144 pixels in up to 35 detection channels simultaneously with up to 16 bit depth (65536 gray values) in all channels. (8, 12 OR 16 bit user selectable.) Pigtailed visible Lasers that are easily upgradeable, like plug and play bayonet mounting for easy maintenance and reliable, and reproducible operation without mirrors affecting alignment. Automatic brightness compensation during the acquisition of z stacks by stepped incrementation of the excitation (laser intensity) and the detection gain (detector sensitivity). Microscope should incorporate a 34-Channel Quasar(Spectral) Detector, consisting of calibrated 32-Array PMTs and two flanking single PMT detectors, which enables image acquisition with freely definable emission spectra and advanced spectral acquisition and analysis. Also, Hardware supports simultaneous acquisition from 34 channels plus TPMT and 2 additional detectors for upto 37 simultaneous 16 bit inputs(6KX6K). Calibration and linearization of the 32-Array PMT detector and the two flanking single PMTs, all 34-channels are needed for spectral acquisition and analysis. A 34-Channel PMT detector (PMT-array with 32 PMTs and two flanking single PMTs) Fast parallel acquisition in one single scan of the entire spectral range as a lambda stack (391-749 nm) covered by the 34-Channel QUASAR Detector. This is needed for analyzing living cells, e.g. colocalization studies and FRET-experiments. It Will support up to 10 different fluorescent dyes can be imaged and separated simultaneously. 2) Spectral Features Supported: Highly efficient holographic grating and Spectral recycling loop. Reproducible high resolution spectral data acquisition with 3.2 nm 4.9 nm or 10nm steps through sequential spectral scanning (10nm parallel scanning with the 34 channel only). Online fingerprinting capability. 3) Software Features will include: Smart Setup (Standard) fully integrated Software based optics configuration module. Intuitive and Simple software control of Hardware Configurations based on selection of fluorochromes. Optimal hardware settings for Channel unmixing are suggested within the Smart Setup Software tool. Real time electronics - supports multitasking module access while data collection in progress - i.e. LIVE HISTOGRAMS, PROFILES, 3D reconstruction, unmixing, RICS, ROI plotting, View modes- allows off line data management of previously collected images possible while scanning. Individual collimation of the UV and the NIR Lasers for precise overlay of all excitation wavelengths. Transmitted light PMT (T-PMT) will be used for simultaneous imaging of DIC. Collimating Optic for beam focusing of IR to VIS wavelengths. Optical Correction for individual objective lenses via motorized collimator optics can be preset for any lens. The software should automatically recall positions for that lens. System self-test tool, with an easy to use maintenance user interface in combination with the calibration objective that allows automated pinhole adjustment and automatic scanner calibration, and securing optimal system performance.. The following factors will be used to evaluate offers: price, warranty and technical capability to meet required specifications. Place of delivery is NIH/NIAID, Bethesda, MD 20892. The FOB point will be Destination. This will be a firm-fixed price contract. The following Federal Acquisition Regulations provisions and clauses apply to the acquisition: FAR 52.212-1, Instructions to Offerors, Commercial Items; FAR 52.212-3, Offeror Representations and Certifications-Commercial Items; FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders, Commercial Items; FAR 52.204-7, Central Contractor Registration; and FAR 32.703-2, Availability of Funds, FAR 52.232-37, Payment by Electronic Funds Transfer Central Contractor Registration. In order to be considered for an award, an offeror must have completed the online electronic Representations and Certifications located at http://orca.bpn.gov/ in accordance with FAR 4.1201(a). By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the CCR at www.ccr.gov/ prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation [Note: Lack of registration in the Central Contractor Registration will make an offeror ineligible for award.] All responsible sources may submit an offer that will be considered by the Agency. Offers must be submitted no later than 5:00 P.M. Eastern Daylight Time on Thursday, August 27, 2009. For delivery of responses through the Postal Service, the address is NIH/NIAID/AMOB, 10401 Fernwood Drive, Suite 2NE70, Room 2NE22B, MSC/2811 Bethesda, Maryland 20892-4812. E-mail and Fax submissions are not authorized. Requests for information concerning this requirement must be submitted in writing, and can be faxed to 301-480-0469, or e-mailed to rodriguezra@niaid.nih.gov. It is the vendor's responsibility to confirm receipt of all quotations and/or questions by the closing date of this announcement by contacting Reyes Rodriguez at 301-402-5770. Collect calls will not be accepted.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/AMOB/RFQ9081/listing.html)
- Place of Performance
- Address: The National Institutes of Health NIAID, 10401 Fernwood Rd RM 2NE70, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN01908876-W 20090814/090813000545-c5417f655eee323c8f332344bb8a70e5 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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