SOLICITATION NOTICE
66 -- G:Box Chemi HR16 Gel Documentation System
- Notice Date
- 4/7/2009
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- NOI1011422
- Archive Date
- 5/2/2009
- Point of Contact
- Liem T Nguyen,, Phone: 3014358780
- E-Mail Address
-
ln18x@nih.gov
- Small Business Set-Aside
- N/A
- Description
- The Institutes of Health (NIH), National Institute on Drug Abuse (NIDA) on behalf of National Institute of Neurological Disorders and Stroke (NINDS) intends to procure on a sole source basis a gel documentation and analysis system from SYNGENE, 5108 Pegasus Court, Frederick, MD 21704. This acquisition will be processed under FAR Part 12 - Acquisition for Commercial Itenms and will be made pursuant to the authority of FAR 13.5 to use Simplified Acquisition Procedure for commercial items. The G-Box Chemi HR16, manufactured by Syngene, is a gel documentation and analysis system. Using its UV transilluminator, researchers can capture and analyze images of DNA gels stained with ethidium bromide or SYBR Green. Visible light applications include viewing and analyzing gels stained with silver stain or coomassie blue (protein gels), tissues, slides and films. The GBox is also capable of detecting and analyzing chemiluminescent samples, for example, western blots. Additional applications include capture and analysis of spot blots and an ability to image a wide range of fluorescent samples. The software provided for analysis of samples is excellent and user friendly. This instrument is manufactured locally and has a 3 year warranty. The principal goal of the NINDS Synaptic Function Unit (SFU) is to study the molecular mechanisms underlying neurotransmitter release and its modulation. SFU scientists rely on a combination of techniques and equipment to conduct research. Purchasing this system will permit NINDS/SFU scientists to analyze DNA and protein studies, both of which are an integral part of all of the projects in SFU lab. The simple design of the G-Box gives NINDS-SFU the flexibility to configure the machine for NINDS' requirement. The camera and lens include PC keyboard control of settings including aperture, zoom and focus, and these settings can be saved and recalled for future captures. It is found that the GeneSnap image capture software very easy to navigate. In particular, the fully automatic package that controls the camera integration, exposure, lens and capture options, with auto focus configurations and focus indicator is a big advantage of this machine. Considering the number of users in NINDS-SFU lab and the NINDA-SFU flexibility to allow individuals from other labs to use NINDS-SFU system, a more automated lens (aperture, focus, zoom) and exposure (auto exposure or series capture, for example) will best fit NINDS-SFU's needs maintenance-wise. The zoom lens allows NINDS-SFU staff to maximize use of available camera pixels independent of sample size. The camera includes 8 separate aperture settings, which will maximize the image intensity control for optimal image capture. The darkroom has an automatic door lock for measurements over 30 seconds, thus preventing the accidental opening of the darkroom during critical long exposures. During data capture, NINDS-SFU can receive up to 5 megapixel image output allowing multi-level zooming of the image with no pixilation of the data. NINDS-SFU staff also have the flexibility to control image sensitivity by the binning mode selected. The GeneSnap software utilizes auto lane finding, auto band finding and baseline correction mode, which minimizes user bias when analyzing data and ensures repeatability. The software also includes the rolling disk baseline correction algorithm, which is an advanced algorithm that permits accurate separation of data from noise independent of width of bands, and a data smoothing algorithm to eliminate false positives related to background noise. Finallly, as the ever expanding list of fluorescent labels available requires an array of EPI and transillumination light sources, NINDS-SFU can incorporate more advanced lighting for these applications with a simple upgrade which will allow the use of these technologies in the future without having to replace the gel documentation system. The G:Box Chemi HR16 Gel Documentation System and the accompany software are designed and manufactured by SYNGENE. SYNGENE is the only known source to NINDS-SFU who can provide this system. This is not a solicitation for competitive quotations. However, if any interested party believes it can perform the requirement as detailed the vendor may submit a statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NIDA/NINDS to determine if it can meet the above specifications described herein. An original and one copy of the capability statement must be received in the Office of Acquisitions, NIDA, on or before 2:00 PM ET April 17, 2009. All questions must be in writing and can be emailed to Liem T Nguyen at ln18x@nih.gov or faxed to 301-480-1358 no later than 2:00 PM ET April 15, 2009. A determination by the Government not to compete this proposed acquisition based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determinng whether to conduct a competitive procurement. In order to receive an award from the NIDA vendor must be registered in the Online Representations and Certifications Applications (ORCA) at http://orca.bpn.gov. In addition, vendor must be registered in the Central Contractor Registration (CCR) at www.ccr.gov. No collect calls will be accepted. Please reference announcement number 1011422 on all correspondence.
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