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FBO DAILY ISSUE OF NOVEMBER 17, 2007 FBO #2182
SOURCES SOUGHT

R -- Yeast Two-Hybrid Analysis of Proteins

Notice Date
11/15/2007
 
Notice Type
Sources Sought
 
NAICS
541990 — All Other Professional, Scientific, and Technical Services
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 10401 Fernwood Drive, Suite 2NE70, MSC 4811, Bethesda, MD, 20817, UNITED STATES
 
ZIP Code
00000
 
Solicitation Number
Reference-Number-1150
 
Response Due
11/29/2007
 
Archive Date
2/1/2008
 
Point of Contact
Amber Harris, Contract Specialist, Phone 301-495-3419, Fax 301-480-0689, - Terrie Nestor, Contracting Officer, Phone 301-402-6790, Fax 301-480-0689
 
E-Mail Address
harrisam@mail.nih.gov, tnestor@niaid.nih.gov
 
Description
The National Institute of Allergy and Infectious Diseases (NIAID), Acquisitions Management and Operations Branch (AMOB) is seeking sources that can provide yeast two-hybrid analysis of proteins. Offerors must be capable of analyzing each protein as multiple overlapping fragments engineered as DNA-binding domain constructs (DBD Constructs); preparing custom activation domain libraries; generating and screening each of the DBD Constructs against up to three different activation domain libraries; reproducing all interactions in na?ve yeast and confirming specificity using multiple microbial DBD Construct controls; providing continuous access to the protein interaction data via a secure, web-based interface; and providing access to a curated database of publicly reported protein-protein interactions. Offerors must have significant operational experience utilizing yeast two hybrid screening technology to detect host-pathogen protein-protein interactions. NIAID intends to award a one year contract beginning on or about October 1, 2008 with the option for four additional contract years. This is not a request for proposals. The intention of this announcement is to survey the market for potential offerors. Potential offerors must provide a capability statement to Amber Harris at harrisam@niaid.nih.gov on or before November 29, 2007 at 3:00pm. Capability statements must indicate the business size of the company.
 
Record
SN01452892-W 20071117/071115223507 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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