MODIFICATION
A -- The Norway Mother and Child Cohort Study (MoBa): Continued Specimen Collection, and Tools to Enhance Use and Collaboration
- Notice Date
- 3/13/2006
- Notice Type
- Modification
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Office of Acquisitions, Office of Management P.O. Box 12874, 79 T.W. Alexander Dr, Bldg 4401, RTP, NC, 27709
- ZIP Code
- 27709
- Solicitation Number
- NIH-ES-06-04
- Response Due
- 4/13/2006
- Archive Date
- 4/28/2006
- Point of Contact
- Carolyn Flowers, Contract Specialist, Phone 919-541-0425, Fax 919-541-2712, - Denise Tyre, Procurement Technician, Phone 919-316-4686, Fax 919-541-2712,
- E-Mail Address
-
flowers3@niehs.nih.gov, tyre@niehs.nih.gov
- Description
- The National Institute of Environmental Health Sciences intends to negotiate with the National Institute of Public Health in Norway to collect, process, store, and manage specimens, and to develop tools to enhance use of the specimen samples and collaboration in conjunction with the Norway Mother and Child Cohort Study (MoBa). In the MoBa study, approximately 100,000 pregnant women will be enrolled during the 17th week of pregnancy; these women and their offspring will be followed until the offspring are adults. Blood and urine are collected from the women, who also complete a series of questionnaires about themselves and their offspring. The goals of the study are manifold, but the study primarily will serve as a flexible platform from which a wide variety of studies can be done using the samples and associated data. Increasing the number of subjects with environmental specimens will: (1) increase the statistical power in studies of more frequent outcomes to detect gene-environment interactions; (2) give adequate statistical power to study environmental determinants of rare diseases such as autism, cerebral palsy, hypospadias, and schizophrenia; and (3) increase the ability to conduct a large number of studies, especially for more frequent outcomes. The MoBa study was initiated by and run by the National Institute of Health in Norway. Specimen collection began in 1999. In 2002, NIEHS scientists began having additional specimen material collected from the pregnant women to enhance the ability to evaluate associations between environmental exposures during pregnancy and subsequent health outcomes in the offspring. NIEHS is currently supporting further specimen collection in conjunction with the MoBa study. No other source has access to the MoBa cohort or the related specimens and data, and no other source has a large enough study in which both blood and urine specimens were collected to effectively meet NIEHS? needs. The National Institute of Health in Norway is the only source capable of performing NIEHS? requirement. Authority: 41 U.S.C. 253(c)(1), as set forth in FAR 6.302-1(b)(1) and HHSAR 306.302-1. See Numbered Note 22. NOTE: THIS NOTICE WAS NOT POSTED TO FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (13-MAR-2006). IT ACTUALLY APPEARED OR REAPPEARED ON THE FEDBIZOPPS SYSTEM ON 14-MAR-2006. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
- Place of Performance
- Address: PO Box 4404 Nydalen, NO-0403, Oslo,
- Country: Norway
- Country: Norway
- Record
- SN01006216-W 20060316/060314212916 (fbodaily.com)
- Source
-
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