PRESOL | B | Hypermutation of Shark Immunoglobulins

FBO DAILY ISSUE OF JANUARY 13, 2005 FBO #1144
SOLICITATION NOTICE

B -- Hypermutation of Shark Immunoglobulins

Notice Date: 1/11/2005
Notice Type: Solicitation Notice
NAICS: 541690 — Other Scientific and Technical Consulting Services
Contracting Office: Department of Health and Human Services, National Institutes of Health, National Institute on Aging, 5600 Nathan Shock Drive, Baltimore, MD, 21224
ZIP Code: 21224
Solicitation Number: LMG166
Response Due: 2/10/2005
Archive Date: 2/25/2005
Description: The National Institutes of Health, NIA-IRP intends to negotiate on a sole source basis with the University of Maryland School of Medicine, Department of Microbiology and Immunology for a project titled "Hypermutation of Shark Immunoglobulins". The University will immunize sharks, collect peripheral blood lymphocytes, and analyze DNA for hypermutation. This will involve several molecular biology techniques to examine various immunoglobulin genes for mutations. The presence of uracils, an intermediate in mutation, can be detected by ligation-mediated PCR and analyzed by gels. If the gel results look promising, the results can be confirmed by the DNA sequencing.
Place of Performance: Address: 655 W. Baltimore Street, Baltimore, MD; Zip Code: 21201; Country: USA
Record: SN00732867-W 20050113/050111211634 (fbodaily.com)
Source: FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

| FSG Index | This Issue's Index | Today's FBO Daily Index Page |