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FBO DAILY ISSUE OF AUGUST 27, 2004 FBO #1005
SOLICITATION NOTICE

66 -- Minstrel I bench top imaging system

Notice Date

8/25/2004
 

Notice Type

Solicitation Notice
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852
 

ZIP Code

20852
 

Solicitation Number

NCI-40143-NG
 

Response Due

9/9/2004
 

Archive Date

9/24/2004
 

Point of Contact

Malinda Holdcraft, Purchasing Agent, Phone (301) 402-4509, Fax (301) 402-4513, - Renita Smith, Contract Specialist, Phone 301-496-8612, Fax 301-480-0241,
 

E-Mail Address

holdcram@exchange.nih.gov, rs442i@nih.gov
 

Description

The National Cancer Institute (NCI), Laboratory of Cell Biology (LCB), Macromolecular Crystallography Unit (MCU), plans to procure on a sole source basis a Minstrel I crystal imaging robot for crystallization from Rigaku/MSC, Inc., 9009 New Trails Drive, The Woodlands, Texas 77381. The North American Industry Classification System Code is 334516 and the business size standard is 500 employees. The supplies and services herein are being procured in accordance with the simplified acquisition procedures authorized by FAR Part 13. The NCI, LCB, studies structure and function of macromolecular assemblies, especially those related to cancer development, treatment, and prevention, primarily using the X-ray crystallographic methodology and requiring a facility for protein crystal growth for X-ray diffraction experiment and for data collection. Our project focuses on the crystallization and structure determination of integral membrane proteins involved in cellular multi-drug resistance (MDR). The difficulties involved in membrane protein structure determination by X-ray crystallography lie in the fact that it is extremely hard to produce large amount of membrane proteins and large amount of the membrane protein surface is hydrophobic, which defies crystallization attempts. We would like to purchase a crystal-imaging robot for examining 96-well crystallization plates, either in sitting drop or in hanging drop, or in micro-batch format. The Minstrel ITM crystal imaging system is an integrated system designed to fit on a lab bench. It is a fully modular and expandable automated protein crystal imaging and analysis system. With its extensive list of options, the Minstrel I can be configured to meet a broad range performance requirements, from low-throughput research applications to demanding high-throughput drug discovery programs. The Minstrel I utilizes an ultra-high resolution imaging system that can quickly and consistently image hanging drop, sitting drop, and microbatch experiment in a broad range of plate types. A programmable light source optimizes the imaging conditions for each drop and plate type. Minstrel I will greatly relieve the physical stress of an individual as a result of manual inspection of numerous crystallization plates. Minstrel I provides highest resolution possible for imaging. Minstrel I is flexible, modular and upgradable, simple to use, has a superior data annotation system, and raid 5 data storage. The crystal imaging robot must be able to handle various crystallization plates such as SBS or linbro/BDX foot print. The bench top design should have a foot print 21"x21" or less. It should have a 5 mega pixel resolution color camera for high quality images with 0.7 to 4.5 x zoom lens with automatic zoom and focus. The robot should also have automatic drop location capability with programmable LED white-light ring light source for optimal lighting of all plate types. It should possess an image database and can be operated in a temperature range between 4 ?C and room temperature. Manual control of camera, lens, lighting and robotics are possible. Rigaku/MSC, Inc is the only source known to the NCI that designs and manufactures equipment and reagents, and packages these products specifically for protein crystallization experiments. This is not a request for competitive quotation. However, if any interested party believes it can perform the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other furnished information must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform this requirement. Capability statements must be received in the contracting office by 1:00 PM EST, September 9, 2004. If you have any questions they must be submitted in writing to Malinda Holdcraft, Purchasing Agent, at holdcram@exchange.nih.gov or by fax 301-402-4513. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Solicitation number NCI- 40143-NG must be stated on all correspondence.
 

Place of Performance

Address: Bethesda, MD

Zip Code: 20892

Country: USA
 

Record

SN00653566-W 20040827/040826074635 (fbodaily.com)
 

Source

FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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