SOLICITATION NOTICE
66 -- Instruments and Laboratory Equipment
- Notice Date
- 6/13/2003
- Notice Type
- Solicitation Notice
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 10401 Fernwood Drive, Suite 2NE70, MSC 4811, Bethesda, MD, 20817
- ZIP Code
- 20817
- Solicitation Number
- NOI3063
- Response Due
- 6/30/2003
- Archive Date
- 7/15/2003
- Point of Contact
- Tonia Alexander, Purchasing Agent, Phone 301-402-6338, Fax 301-480-3695, - Sylvia Robinson, Purchasing Agent, Phone 301-402-2284, Fax 301-480-3695,
- E-Mail Address
-
talexander@niaid.nih.gov, srobinson@niaid.nih.gov
- Description
- 17. This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are not being requested and a written solicitation will not be issued. The solicitation number for this acquisition is NOI3063 and is being issued as a Notice of Intent (NOI). The incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2001-14. This acquisition will be processed under Simplified Acquisition Procedures (SAP) and is not a small business concern. The associated North American Industry Classification System (NAICS) Code 339111, which has a business size standard of 500. The National Institute of Allergy and Infectious Diseases intends to procure an AKTA Explorer 100A Liquid Chromatography System with an attachment Fraction Collector 950 from the manufacture and the distributor Amersham Biosciences. The MVDU currently has two AKTA systems in the laboratory. To introduce NIH employees to a new system at this time would be costly to the government, posing a threat to on-going experiments as well as to educate employees on a new system. Consistency of using this instrument will allow uninterrupted service as well as continuity of results. The AKTA System must be able to 1) thoroughly develop purification processes that provide the highest quality and quantity of product, 2) provide access to post-docs for professional development, and 3) provide some redundancy for when we experience equipment failure, which has hindered our efforts recently. The AKTA Explorer 100A chromatography system is a critical instrument for development of purification processes that meet the requirements of current industrial purification standards. The system range in flow rates that permits both small scale and pilot plant scale development work. Data from pilot plant purification work in-house is used to technology transfer process to a contract manufacturer. The instruments documentation package provides relevant information regarding process validation for supporting and IND submission. The system enables the automated screening of up to 8 chromatography resins in parallel, and moderate throughput studies on the effects of buffer concentrations such as pH and conductivity on purification. This system has the labiality to purify bimolecular from complex starting materials derived from cell lysates, tissue homogenates and recombinant protein expression systems. The system will be able to perform separations based on a variety of sample characteristics, such as molecular weight, net surface charge, hydrophobicty, while retaining biological activity. This instrument is to allow a fast use method and process development and scale-up for proteins, peptides and nucleic acids. The AKTA Explorer 100A is designed for all chromatographic techniques employed in method and process development, offering microgram to gram scale purification. A high level of automation is achieved through UNICORN control software. A method wizard minimizes preparation run-time and repetitive task while retaining flexibility for easy manual operation. Samples can be applied at flow rates up to 50 ml/min and fractions can be collected without spillage at flow rates up to 100 ml/min. The system contains two on-line air sensors, which will assure that air is not pumped onto the columns. In that event that buffers are depleted, the system will take corrective action. The system has an UV-900 monitor that can simultaneously monitor three different wavelengths in a range of 190-700nm. The monitor bandwidth is 4nm with a wavelength accuracy of plus or minus 2nm. The monitor includes a 10mm flow cell. The system is a ph/900 monitor that can simultaneously monitor that measures in-line conductivity, temperature and pH. The monitor allows for auto-ranging between any two ionic strength buffers with conductivity range of luS/cm to 999mS/cm. The pH range is 0-14 with plus or minus 0.1-pH unit accuracy, temperature compensated. The attachment Fraction Collector 950 model is for use with the AKTA design chromatography system. It is fully controlled from the UNICORN software. The FRAC-950 offers two independent ways of preventing sample loss and the highest flexibility in the choice of collection mode. Fractions are collected in microplates (over 384 fractions, up to 2.5ml per fraction), a variety of test tube sizes (up to 250ml per fraction). Different fraction sizes can be collected during different stages of a separation. In standard fraction collections mode, fractions can be collected in 96-well microplates (up to four) and 12, 18 and 30 mm standards tubes. Warranted from date of shipment for period of one year. The following FAR provisions and clauses apply to this acquisition: FAR 52.212-1 Instructions to Offerors Commercial Items; FAR 52.212-3 Offerors Representations and Certifications Commercial Items; FAR 52.212-4, Contractor Terms and Conditions Commercial Items; FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items applies to this acquisition. A completed copy of provisions FAR 52.212-3 Offerors Representations and Certifications Commercial Items must be included. Copies of the aforementioned clauses are available upon request by telephone to Ms. Tonia Alexander at (301) 496-2607. Offers must be submitted no later 5:00P.M. Eastern Daylight Time (EDT), June 30, 2003 to Tonia Alexander. For delivery through the postal service the address is NIH/NIAID/AMOB, 10401 Fernwood Drive, Suite 2NE70, Room/2NE62C, MSC/4812, Bethesda, Maryland 20817-4812. Electronic submission will not be accepted. Request for information concerning this requirement are to be addressed to Ms. Tonia Alexander at (301) 496-2607. Collect calls will not be accepted. All responsible sources may submit an offer that will be considered by this agency.
- Place of Performance
- Address: National Institute of Health, Bethesda, Maryland
- Zip Code: 20892
- Country: USA
- Zip Code: 20892
- Record
- SN00347342-W 20030615/030613213839 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |