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FBO DAILY ISSUE OF MAY 11, 2002 FBO #0160
SOLICITATION NOTICE

66 -- Two Photon Laser

Notice Date

5/9/2002
 

Notice Type

Solicitation Notice
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Room 604, Rockville, MD, 20852
 

ZIP Code

20852
 

Solicitation Number

NCI-RFQ-20035-NV
 

Response Due

5/20/2002
 

Archive Date

6/4/2002
 

Point of Contact

Deborah Moore, Purchasing Agent, Phone (301) 496-8609, Fax (301) 402-4513, - David Keefer, Contracting Officer, Phone (301) 435-3801, Fax (301) 480-0309,
 

E-Mail Address

dm170b@nih.gov, dk63h@nih.gov
 

Description

This is a combined synopsis/solicitation for commercial items, prepared in accordance with the format in FAR 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation, No. RFQ-NCI-20035-NV includes all applicable provisions and clauses in effect through FAR FAC 2001-06. The acquisition is being made in accordance with the test program for using simplified procedures for certain commercial items authorized in FAR 13.6. The North American Industry Classification code is 334516, and the business size standard is 500 Employees. However, this solicitation is not set-aside for small business. Background: The Developmental Neural Plasticity Unit DNP of the National Institutes of Neurological Disorders and Stroke (NINDS) is currently engaged in the study of fundamental mechanisms that underlie the development and remodeling of neuronal circuits in the mammalian olfactory system. These studies use expressed fluorescent proteins (GFP, YFP, CFP, dsRed) in the olfactory system and will focus on imaging primary afferents as they converge and form synapses onto the olfactory bulbs. Since these fluorophores have highly overlapping emission spectra the ability to separate their individual fluorescent signals is critical to the outcome of the experiments. Requirement: . High power 2-photon laser system with wide tuning range. The tunibility (700nm and 1000nm) is essential, a high-power (10W) laser source is required; to reduce phototoxicity, that power is confined to intense, ultrafast (100 MHz) pulses of light (each pulse is <100 fs in duration). The laser must be passively modelocked and use a variable saturable absorber for preferential control between CW and modelocked operation since this configuration provides a means for controlling loss differential as well as gain differential which is necessary for reliable operation and control of the spectral purity of the modelocked output. This allows for two different methods of mode-locking in order to achieve the highest degree of reliability. This is essential since any CW component can kill our samples and destroy our experiments. The laser must have an internal diagnostic system which includes: (1) an autoranging five decade fluorescence detector/power meter to facilitate alignment and optimization, (2) a monitor to verify CW spectral content to insure spectral integrity of output and maintain pure modelocked operation, and (3) a biased, fast photodiode to provide a synchronization signal for detector triggering. This feature facilitate the day-to-day operation of the laser. The laser must have a thermally-compensated resonator so that the system automatically and passively offsets the effects of thermal fluctuations in the laboratory that cause drift over long periods of operation. The system should have internal pump laser steering optics for maximum control of the pump beam position into the Ti:Sapphire crystal. This allow for maximum output of the laser by tuning the pump optics. The laser must include a separate CW cavity arm to facilitate alignment and also to produce tunable CW output from the laser. The laser system must have a thermally compensated resonator that automatically offsets the effects of thermal fluctuations to ensures that the Laser System remains stable over long periods of time. It is critical for the experiments that the wavelength, mode-locking and illumination remain stable and do not fluctuate for extended periods of time. Since this laser is an integral component of a larger imaging system that requires precise interfacing with a Zeiss confocal system it is essential that the laser system have extensive proven compatibility. Therefore, a list shall be provided by the vendor of at least 20 laser systems, installed and proven on Zeiss scopes. This list shall include an organizations name, phone number and a contact name for reference. Moreover, since this imaging system is central to our research which involves critically timed developmental experiments typically set in motion weeks ahead of time on a daily staggered fashion, it is crucial that the laser system be available and in full operation on a daily basis or many weeks of experiments will be lost. Therefore, we require that a qualified service person be available within 50 miles of the NIH Bethesda, Maryland campus in order to ensure prompt dependable service The Laser shall be delivered FOB destination to the The Developmental Neural Plasticity Unit DNP of the National Institutes of Neurological Disorders and Stroke (NINDS) in Bethesda, Maryland and be up and running with ALL specified performance features intact and installed no later than September 30, 2002. Offerors must provide descriptive literature, or other materials that demonstrate that their offer meets the foregoing requirements. The contract will be awarded to the responsible offeror with the lowest-price offer that fully meets the requirements of the solicitation. This solicitation incorporates the provisions at FAR 52.212-1, INSTRUCTIONS TO OFFERORS-COMMERCIAL ITEMS, and at FAR 52.212-3, OFFEROR REPRESENTATIONS AND CERTIFICATIONS - COMMERCIAL ITEMS. The latter provision includes the DUNS Number Addendum. The resulting contract will incorporate the requirements of the clause at FAR 52.212-4, CONTRACT TERMS AND CONDITIONS - COMMERCIAL ITEMS, and the requirements contained in paragraphs (a) and (d) of the clause at FAR 52.212-5, CONTRACT TERMS AND CONDITIONS REQUIRED TO IMPLEMENT STATUTES OR EXECUTIVE ORDERS - COMMERCIAL ITEMS - DEVIATION FOR SIMPLIFIED ACQUISITIONS. The contract will also incorporate the following FAR clauses cited in paragraphs (b) and (c) of the latter clause: FAR 52.222-26, EQUAL OPPORTUNITY; FAR 52.222-35, AFFIRMATIVE ACTION FOR SPECIAL DISABLED AND VIETNAM ERA VETERANS; FAR 52.222-36, AFFIRMATIVE ACTION FOR HANDICAPPED WORKERS; FAR 52.222.37, EMPLOYMENT REPORTS ON SPECIAL DISABLED VETERANS AND VETERANS OF VIETNAM ERA; and FAR 52.225-3, BUY AMERICAN ACT - SUPPLIES. Offers are due May 20 at 1:00 p.m. EDT. Facsimile submission are not authorized. Offers must be in writing and should be submitted as follows: (1) one original and two copies of a completed SF 1449, signed by an individual authorized to bind the organization; (2) a Schedule of Offered Supplies/Services containing pricing for the system being offered, published price lists (if applicable), and a delivery schedule; (3) completed Representations and Certifications - Commercial Items, with DUNS Number addendum; (4) descriptive literature indicating that the offer meets the stated requirements; (5) acknowledgment of amendments, if any. The Representations and Certifications must be signed by an authorized representative of the offeror. Full text copies of the Representations and Certifications or other cited provisions and clauses may be obtained from Debbie Moore, Purchasing Agent, on (301) 402-4509 or by fax on (301) 402-4513. Offers and related materials must be submitted to Debbie Moore at the listed address. Offers that fail to furnish the required information or reject the terms and conditions of the solicitation may be excluded from consideration. Please cite the solicitation number on your offer. Any questions must be submitted in writing and may be e-mailed to dm170b@nih.gov or faxed to 301-402-4513. It is the vendors responsibility to call 301-402-4509 to insure questions have been received.
 

Place of Performance

Address: 9000 Rockville Pike, Bethesda, Maryland

Zip Code: 20892
 

Record

SN00074299-W 20020511/020509213118 (fbodaily.com)
 

Source

FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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